Cystitis Major Organ Infl ammation

13.8 Summary

Radiation-induced toxicity is a real possibility that is likely underrecognized in the pediatric population. The pediatric oncologist must be aware of potential RT-induced complications based on the radiation fi eld, RT dose, fraction- ation, concurrent chemotherapy and potential underlying patient morbidities. A multidisci- plinary approach is often required to plan for and treat any potential complications. Although evi- dence-based prevention and treatment strategies are generally lacking in the pediatric literature, the adult literature, through both evidence and consensus guidelines, provides an excellent resource from which to extrapolate reasonable management plans. References Abid SY, Malhotra V, Perry MC 2001 Radiation-induced and chemotherapy-induced pulmonary injury. Curr Opin Oncol 13:242–248 Abramoff MM, Lopes NN, Lopes LA et al 2008 Low- level laser therapy in the prevention and treatment of chemotherapy-induced oral mucositis in young patients. 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