13.8 Summary
Radiation-induced toxicity is a real possibility that is likely underrecognized in the pediatric
population. The pediatric oncologist must be aware of potential RT-induced complications
based on the radiation fi eld, RT dose, fraction- ation, concurrent chemotherapy and potential
underlying patient morbidities. A multidisci- plinary approach is often required to plan for and
treat any potential complications. Although evi- dence-based prevention and treatment strategies
are generally lacking in the pediatric literature, the adult literature, through both evidence and
consensus guidelines, provides an excellent resource from which to extrapolate reasonable
management plans.
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