Hubungan Penderita Arthritis Kronis Yang Ditegakkan Secara Kuesioner Dengan Tes Serologis Penyakit Lime
ABSTRAK
Latar belakang: Studi objektif inii menentukan sero-prevalensi penyakit lime di
kecamatan Sibolangit, Sumatera Utara, Indonesia. Studi dilakukan secara cross
sectional dengan pendekatan karakteristik epidemiologi dan dikonfirmasi tes
serologis (ELISA IgG lime)
Material dan Metode: Studi mencakup sekitar 41 individu sehat, berkisar 18-40
tahun, individu yang mempunyai riwayat terpapar tungau dan mempunyai gejala
klinis arthritis kronis tidak menemuhi kriteria RA menurut ACR 1987 dan
EULAR 2010, OA, gout dan arthritis septik. Setiap subjek penelitian mengisi
kuesioner, pemeriksaan darah rutin, serumasam urat dan tes ELISA IgG lime.
Hasil: Dijumpai 7,3% positif lime dan 2,4% borderline pada sampel penelitian.
Tiga sampel positif lime dilakukan pemeriksaan darah lanjutan mencakup profil
rheumatologi. Ditemukan 3 sampel positif rheumatoid factor, 2 sampel positif anti
MCV dan 1 sampel CRP sedikit meningkat. Subjek penelitian positif lime
mempunyai skoring EULAR 2010 normal
Kesimpulan: Penyakit lime pertama kali ditemukan di Indonesia, di Kecamatan
Sibolangit, Sumatera Utara dan didapati ada hubungan arthritis kronis dengan tes
serologis lime.
Kata kunci: penyakit lime, arthritis kronis, ELISA IgG lime
Universitas Sumatera Utara
ABSTRACT
Background: The objective of the study was to determine sero-prevalence lyme
disease in Sibolangit, North Sumatra, Indonesia. The aim of presented cross
sectional by epidemiology characteristic and confirmed by serologic test (ELISA
IgG lyme)
Material and Method: The study was conducted among 41 healthy individuals,
aged 18-40, who declared being bitten by ticks and having chronic arthritis no
fulfill RA with criteria ACR 1987 and EULAR 2010, OA, gout and septic
arthritis. Every samples were done by questionnaire, routine blood test, uric acid
serum and ELISA IgG lime test.
Result: A 7,3% presence of positive IgG lime and 2,4% borderline, were
dectected all investigation samples. 3 samples positive lyme needs further
investigation laboratorium blood sampling to check rheumatology marker. We
found 3 samples positive rheumatoid factor, 2 samples had positive anti MCV
(mutates citrullinated vimectin) and CRP slightly increased in 1 sample. Sample
positive lyme had normal scoring (EULAR 2010)
Conclusion: The first case found lyme disease in Indonesia, especially in
Sibolangit, North Sumatra and having correlation arthritis chronis with serologic
lyme test.
Keyword: lime disease, chronic arthritis, IgG lime ELISA
Universitas Sumatera Utara
Latar belakang: Studi objektif inii menentukan sero-prevalensi penyakit lime di
kecamatan Sibolangit, Sumatera Utara, Indonesia. Studi dilakukan secara cross
sectional dengan pendekatan karakteristik epidemiologi dan dikonfirmasi tes
serologis (ELISA IgG lime)
Material dan Metode: Studi mencakup sekitar 41 individu sehat, berkisar 18-40
tahun, individu yang mempunyai riwayat terpapar tungau dan mempunyai gejala
klinis arthritis kronis tidak menemuhi kriteria RA menurut ACR 1987 dan
EULAR 2010, OA, gout dan arthritis septik. Setiap subjek penelitian mengisi
kuesioner, pemeriksaan darah rutin, serumasam urat dan tes ELISA IgG lime.
Hasil: Dijumpai 7,3% positif lime dan 2,4% borderline pada sampel penelitian.
Tiga sampel positif lime dilakukan pemeriksaan darah lanjutan mencakup profil
rheumatologi. Ditemukan 3 sampel positif rheumatoid factor, 2 sampel positif anti
MCV dan 1 sampel CRP sedikit meningkat. Subjek penelitian positif lime
mempunyai skoring EULAR 2010 normal
Kesimpulan: Penyakit lime pertama kali ditemukan di Indonesia, di Kecamatan
Sibolangit, Sumatera Utara dan didapati ada hubungan arthritis kronis dengan tes
serologis lime.
Kata kunci: penyakit lime, arthritis kronis, ELISA IgG lime
Universitas Sumatera Utara
ABSTRACT
Background: The objective of the study was to determine sero-prevalence lyme
disease in Sibolangit, North Sumatra, Indonesia. The aim of presented cross
sectional by epidemiology characteristic and confirmed by serologic test (ELISA
IgG lyme)
Material and Method: The study was conducted among 41 healthy individuals,
aged 18-40, who declared being bitten by ticks and having chronic arthritis no
fulfill RA with criteria ACR 1987 and EULAR 2010, OA, gout and septic
arthritis. Every samples were done by questionnaire, routine blood test, uric acid
serum and ELISA IgG lime test.
Result: A 7,3% presence of positive IgG lime and 2,4% borderline, were
dectected all investigation samples. 3 samples positive lyme needs further
investigation laboratorium blood sampling to check rheumatology marker. We
found 3 samples positive rheumatoid factor, 2 samples had positive anti MCV
(mutates citrullinated vimectin) and CRP slightly increased in 1 sample. Sample
positive lyme had normal scoring (EULAR 2010)
Conclusion: The first case found lyme disease in Indonesia, especially in
Sibolangit, North Sumatra and having correlation arthritis chronis with serologic
lyme test.
Keyword: lime disease, chronic arthritis, IgG lime ELISA
Universitas Sumatera Utara