Hasil Pengukuran Volume Telapak Kaki Tikus Putih yang diberi Ekstrak Herba Ajeran 1,0 gkgBB Per Oral Perlakuan Volume telapak kaki tikus (mm

  

LAMPIRAN A

HASIL PENGUKURAN VOLUME TELAPAK KAKI TIKUS DAN AUC

  % INHIBISI RADANG Hasil Pengukuran Volume Telapak Kaki Tikus Putih yang diberi PGA 3% b/v Per Oral

  Perlakuan Volume telapak kaki tikus (mm

  3 ) dan AUC jam ke- AUC

  2

  4

  6

  8

  1 V 12,56 25,12 37,68 25,12 12,56 AUC 37,68 62,80 62,80 37,68 200,96

  2 V 12,56 37,68 37,68 18,84 18,84 AUC 50,24 75,36 56,52 37,68 219,80

  3 V 12,56 37,68 37,68 25,12 18,84 AUC 50,24 75,36 62,80 43,96 232,36

  4 V 12,56 31,40 37,68 18,84 18,84 AUC 43,96 69,08 56,52 37,68 207,24

  5 V 12,56 31,40 31,40 31,40 18,84 AUC 43,96 62,80 62,80 50,24 219,80

  Rerata ± SD 216,03 ± 12,24 Hasil Pengukuran Volume Telapak Kaki Tikus Putih yang diberi Ekstrak Herba Ajeran 0,5 g/kgBB Per Oral Perlakuan Volume telapak kaki tikus (mm

  3 ) dan AUC jam ke- AUC

  3 ) dan AUC jam ke- AUC

  5 V 12,56 18,84 18,84 12,56 12,56 AUC 31,40 37,68 31,40 25,12 125,60

  4 V 12,56 25,12 18,84 18,84 18,84 AUC 37,68 43,96 37,68 37,68 157,00

  3 V 12,56 31,40 18,84 12,56 12,56 AUC 43,96 50,24 31,40 25,12 150,72

  2 V 12,56 31,40 25,12 25,12 12,56 AUC 43,96 56,52 50,24 37,68 188,40

  1 V 12,56 25,12 12,56 12,56 12,56 AUC 37,68 37,68 25,12 25,12 125,60

  8

  6

  4

  2

  Hasil Pengukuran Volume Telapak Kaki Tikus Putih yang diberi Ekstrak Herba Ajeran 1,0 g/kgBB Per Oral Perlakuan Volume telapak kaki tikus (mm

  2

  Rerata ± SD 175,84 ± 17,20

  5 V 12,56 31,40 25,12 18,84 18,84 AUC 43,96 56,52 43,96 37,68 182,12

  4 V 12,56 37,68 25,12 25,12 12,56 AUC 50,24 62,80 50,24 37,68 200,96

  3 V 12,56 25,12 18,84 18,84 18,84 AUC 37,68 43,96 37,68 37,68 157,00

  2 V 12,56 25,12 25,12 25,12 12,56 AUC 37,68 50,24 50,24 37,68 175,84

  1 V 12,56 31,40 25,12 12,56 12,56 AUC 43,96 56,52 37,68 25,12 163,28

  8

  6

  4

  Rerata ± SD 149,46 ± 26,04 Hasil Pengukuran Volume Telapak Kaki Tikus Putih yang diberi Ekstrak Herba Ajeran 1,5 g/kgBB Per Oral Perlakuan Volume telapak kaki tikus (mm

  3 ) dan AUC jam ke- AUC

  3 ) dan AUC jam ke- AUC

  5 V 12,56 18,84 12,56 12,56 12,56 AUC 31,40 31,40 25,12 25,12 113,04

  4 V 12,56 18,84 12,56 12,56 12,56 AUC 31,40 31,40 25,12 25,12 113,04

  3 V 12,56 18,84 12,56 12,56 12,56 AUC 31,40 31,40 25,12 25,12 113,04

  2 V 12,56 25,12 18,84 12,56 12,56 AUC 37,68 43,96 31,40 25,12 138,16

  1 V 12,56 25,12 12,56 12,56 12,56 AUC 37,68 37,68 25,12 25,12 125,60

  8

  6

  4

  2

  Hasil Pengukuran Volume Telapak Kaki Tikus Putih yang diberi Fenilbutazon 9,0 mg/kgBB Per Oral Perlakuan Volume telapak kaki tikus (mm

  2

  Rerata ± SD 133,14 ± 6,88

  5 V 12,56 25,12 12,56 12,56 12,56 AUC 37,68 37,68 25,12 25,12 125,60

  4 V 12,56 25,12 18,84 12,56 12,56 AUC 37,68 43,96 31,40 25,12 138,16

  3 V 12,56 25,12 18,84 12,56 12,56 AUC 37,68 43,96 31,40 25,12 138,16

  2 V 12,56 25,12 12,56 12,56 12,56 AUC 37,68 37,68 25,12 25,12 125,60

  1 V 12,56 31,40 12,56 12,56 12,56 AUC 43,96 43,96 25,12 25,12 138,16

  8

  6

  4

  Rerata ± SD 120,58 ± 11,23

  LAMPIRAN B

  HASIL % INHIBISI RADANG E

1 E

  3 Pembanding Tikus 1 24,42 41,86 36,05 41,86 Tikus 2 18,60 12,79 41,86 36,05 Tikus 3 27,32 30,23 36,05 47,67 Tikus 4 6,98 27,32 36,05 47,67 Tikus 5 15,70 41,86 41,86 47,67

  Rerata ± SD

  18,60 ± 7,96

  30,81 ± 12,06

  38,37 ± 3,18

  2 E

  Keterangan : E

  1 = ekstrak herba ajeran 0,5 g/kgBB,

  E

  2 = ekstrak herba ajeran 1,0 g/kgBB,

  E

  3 = ekstrak herba ajeran 1,5 g/kgBB,

  Pembanding = fenilbutazon 9,0 mg/kgBB

  44,18 ± 5,20

  LAMPIRAN C

HASIL PERHITUNGAN JUMLAH LEUKOSIT PADA TIKUS PUTIH

  (/cmm) pada jam ke Kelompok kontrol

  Kelompok E

  8 13730 8500 8700 7200 9750 47880 9576 ± 2492,82

  6 10340 15050 15850 14900 15300 71440 14288 ± 2236,40

  4 9260 7900 14450 11850 13300 56760 11352 ± 2735,56

  2 8210 8650 9000 7200 7800 40860 8172 ± 706,87

  5 7530 8350 7550 6950 7150 37530 7506 ± 536,36

  4 Tikus

  3 Tikus

  2 Tikus

  1 Tikus

  1 Total Rerata ± SD Tikus

  Jumlah leukosit (/cmm) pada jam ke

  Total Rerata ± SD Tikus

  Hasil Perhitungan Jumlah Leukosit Tikus Putih yang diberi PGA 3% b/v Jumlah leukosit

  8 14800 14350 13700 13400 12400 68650 13730 ± 923,04

  6 9900 9550 10000 10600 11650 51700 10340 ± 824,17

  4 9650 9400 8550 8200 10500 46300 9260 ± 913,37

  2 7750 8350 8150 7550 9250 41050 8210 ± 661,82

  5 6600 6950 7800 7350 8950 37650 7530 ± 911,45

  4 Tikus

  3 Tikus

  2 Tikus

  1 Tikus

  Hasil Perhitungan Jumlah Leukosit pada Tikus Putih yang diberi Ekstrak Herba Ajeran 0,5 g/kgBB Per Oral

  Hasil Perhitungan Jumlah Leukosit pada Tikus Putih yang diberi Ekstrak Herba Ajeran 0,1 g/kgBB Per Oral

  Jumlah Kelompok E

  2 leukosit

  Total Rerata ± SD (/cmm) pada

  Tikus Tikus Tikus Tikus Tikus jam ke

  1

  2

  3

  4

  5 8900 7500 8200 7750 8750 41100 8220 ± 608,89 9100 8150 8450 8500 10050 44250 8850 ±

  2 754,16 16800 14200 14450 14300 12650 72400 14480 ±

  4 1486,86 19650 18750 16350 16700 18400 89850 17970 ±

  6 1401,16 11800 10600 10400 10950 8950 52700 10540 ±

  8 1037,67

  Hasil Perhitungan Jumlah Leukosit Pada Tikus Putih yang diberi Ekstrak Herba Ajeran 1,5 g/kgBB Per Oral

  Jumlah Kelompok E

  3 leukosit

  Total Rerata ± SD (/cmm) pada

  Tikus Tikus Tikus Tikus Tikus jam ke

  1

  2

  3

  4

  5 8300 9250 9400 9850 8350 45150 9030 ± 680,62 8900 9700 10200 11550 9350 49700 9940 ±

  2 1018,21 14550 15300 14000 15500 13150 72500 14500 ±

  4 963,72 16200 17800 18650 19250 18200 90100 18020 ±

  6 1151,41 14100 11750 9400 11650 10200 57100 11420 ±

  8 1796,73 Hasil Perhitungan Jumlah Leukosit pada Tikus Putih yang diberi Fenilbutazon 9,0 mg/kgBB Per Oral

  Jumlah leukosit (/cmm) pada jam ke

  Kelompok pembanding Total

  Rerata ± SD

  Tikus

  1 Tikus

  2 Tikus

  3 Tikus

  4 Tikus

  5 10150 12050 9200 10550 9350 51300 10260 ± 1145,86

  2 11300 12900 10000 11500 9750 55450 11090 ± 1272,01

  4 14800 16200 13850 15250 11950 72050 14410 ± 1614,54

  6 17200 17900 15100 18450 13950 82600 16520 ± 1917,88

  8 14100 12150 9950 11800 10250 58250 11650 ± 1667,71

  

LAMPIRAN D

  18.84

  24 Between Groups Within Groups Total Sum of

  20 20.508 779.303

  VOLUME 369.143 4 92.286 4.500 .009 410.159

  Interval for Mean Minimum Maximum ANOVA

  Bound Upper Bound 95% Confidence

  Std. Deviation Std. Error Lower

  37.68 kontrol k1 k2 k3 p Total N Mean

  18.84

  25.12 25 27.3808 5.6983 1.1397 25.0286 29.7330

  31.40 5 21.3520 3.4397 1.5383 17.0811 25.6229

  PERHITUNGAN ONE WAY ANOVA VOLUME TELAPAK KAKI TIKUS Perhitungan One Way Anova Volume Telapak Kaki Tikus Jam ke-2

  25.12

  31.40 5 26.3760 2.8085 1.2560 22.8888 29.8632

  18.84

  37.68 5 26.3760 5.2542 2.3498 19.8520 32.9000

  25.12

  37.68 5 30.1440 5.2542 2.3498 23.6200 36.6680

  25.12

  VOLUME 5 32.6560 5.2542 2.3498 26.1320 39.1800

  

Descriptives

  Squares df Mean Square F Sig. a.

  Uses Harmonic Mean Sample Size = 5.000.

  Lower Bound

  

2

Subset for alpha = .05 Means for groups in homogeneous subsets are displayed.

  1

  N

  FORMULA p k2 k3 k1 kontrol Sig.

  5 21.3520 5 26.3760 26.3760 5 26.3760 26.3760 5 30.1440 5 32.6560 .426 .223

  VOLUME Tukey HSD a

  95% Confidence Interval The mean difference is significant at the .05 level.

  Upper Bound

  Mean Difference (I-J) Std. Error Sig.

  (I) FORMULA kontrol k1 k2 k3 p

• 6.2800 2.8641 .223 -14.8506 2.2906
• 3.7680 2.8641 .685 -12.3386 4.8026

  .0000 2.8641 1.000 -8.5706 8.5706 5.0240 2.8641 .426 -3.5466 13.5946

  .0000 2.8641 1.000 -8.5706 8.5706 5.0240 2.8641 .426 -3.5466 13.5946

  3.7680 2.8641 .685 -4.8026 12.3386 3.7680 2.8641 .685 -4.8026 12.3386 8.7920* 2.8641 .043 .2214 17.3626

  11.3040* 2.8641 .006 2.7334 19.8746

  2.5120 2.8641 .902 -6.0586 11.0826 6.2800 2.8641 .223 -2.2906 14.8506 6.2800 2.8641 .223 -2.2906 14.8506

  Dependent Variable: VOLUME Tukey HSD

  

Multiple Comparisons

• 2.5120 2.8641 .902 -11.0826 6.0586
• 6.2800 2.8641 .223 -14.8506 2.2906
• 3.7680 2.8641 .685 -12.3386 4.8026
• 11.3040* 2.8641 .006 -19.8746 -2.7334
• 8.7920* 2.8641 .043 -17.3626 -.2214
• 5.0240 2.8641 .426 -13.5946 3.5466
• 5.0240 2.8641 .426 -13.5946 3.5466 (J) FORMULA k1 k2 k3 p kontrol k2 k3 p kontrol k1 k3 p kontrol k1 k2 p kontrol k1 k2 k3
• .

  12.56

  12.56

  Within Groups Total

  220.855 20 11.043 1899.353

  VOLUME 1678.498 4 419.625 38.000 .000

  Interval for Mean Minimum Maximum ANOVA

  Bound Upper Bound 95% Confidence

  Std. Deviation Std. Error Lower

  37.68 kontrol k1 k2 k3 p Total N Mean

  Perhitungan One Way Anova Volume Telapak Kaki Tikus Jam ke-4

  18.84 25 21.6032 8.8961 1.7792 17.9311 25.2753

  18.84 5 13.8160 2.8085 1.2560 10.3288 17.3032

  Mean Square F Sig.

  12.56

  25.12 5 15.0720 3.4397 1.5383 10.8011 19.3429

  12.56

  25.12 5 18.8400 4.4406 1.9859 13.3262 24.3538

  18.84

  37.68 5 23.8640 2.8085 1.2560 20.3768 27.3512

  31.40

  VOLUME 5 36.4240 2.8085 1.2560 32.9368 39.9112

  

Descriptives

  Sum of Squares df

24 Between Groups

  Multiple Comparisons Dependent Variable: VOLUME Tukey HSD

  12.5600* 2.1017 .000 6.2709 18.8491 17.5840* 2.1017 .000 11.2949 23.8731 21.3520* 2.1017 .000 15.0629 27.6411 22.6080* 2.1017 .000 16.3189 28.8971

  Lower Bound Upper Bound

  95% Confidence Interval The mean difference is significant at the .05 level.

• 12.5600* 2.1017 .000 -18.8491 -6.2709 5.0240 2.1017 .159 -1.2651 11.3131 8.7920* 2.1017 .004 2.5029 15.0811 10.0480* 2.1017 .001 3.7589 16.3371
• 17.5840* 2.1017 .000 -23.8731 -11.>5.0240 2.1017 .159 -11.3131 1.2651 3.7680 2.1017 .405 -2.5211 10.0571 5.0240 2.1017 .159 -1.2651 11.3131
• 21.3520* 2.1017 .000 -27.6411 -15.>8.7920* 2.1017 .004 -15.0811 -2.5029
• 3.7680 2.1017 .405 -10.0571 2.5211 1.2560 2.1017 .974 -5.0331 7.>22.6080* 2.1017 .000 -28.8971 -16.3189
• 10.0480* 2.1017 .001 -16.3371 -3.
• 5.0240 2.1017 .159 -11.3131 1.2651
• 1.2560 2.1017 .974 -7.5451 5.0331 (J) FORMULA k1 k2 k3 p kontrol k2 k3 p kontrol k1 k3 p kontrol k1 k2 p kontrol k1 k2 k3 (I) FORMULA kontrol k1 k2 k3 p Mean Difference

  (I-J) Std. Error Sig.

• .

  VOLUME a

  Tukey HSD Subset for alpha = .05 FORMULA N

  1

  2

  3 p 5 13.8160 k3 5 15.0720 k2 5 18.8400 18.8400 k1 5 23.8640 kontrol

5 36.4240

Sig. .159 .159 1.000

  Means for groups in homogeneous subsets are displayed.

  a.

  Uses Harmonic Mean Sample Size = 5.000.

  Perhitungan One Way Anova Volume Telapak Kaki Tikus Jam ke-6

  

Descriptives

  VOLUME 95% Confidence Interval for Mean Std. Lower Upper

  N Mean Deviation Std. Error Bound Bound Minimum Maximum kontrol 5 23.8640 5.2542 2.3498 17.3400 30.3880

  18.84

  31.40 k1 5 20.0960 5.2542 2.3498 13.5720 26.6200

  12.56

  25.12 k2 5 16.3280 5.6170 2.5120 9.3536 23.3024

  12.56

  25.12 k3 5 12.5600 2.565E-16 1.147E-16 12.5600 12.5600

  12.56

  12.56 p 5 12.5600 2.565E-16 1.147E-16 12.5600 12.5600

  12.56

  12.56 Total 25 17.0816 5.8800 1.1760 14.6545 19.5087

  12.56

  31.40 ANOVA

  VOLUME Sum of Mean Squares df Square F Sig. Between Groups 482.726

  4 120.682 6.955 .001 Within Groups 347.058 20 17.353 Total

  829.784

  24 a.

  Uses Harmonic Mean Sample Size = 5.000.

  Mean Difference (I-J) Std. Error Sig.

  2 Subset for alpha = .05 Means for groups in homogeneous subsets are displayed.

  1

  N

  FORMULA k3 p k2 k1 kontrol Sig.

  5 12.5600 5 12.5600 5 16.3280 16.3280 5 20.0960 20.0960 5 23.8640 .065 .065

  VOLUME Tukey HSD a

  95% Confidence Interval The mean difference is significant at the .05 level.

  Upper Bound

  Lower Bound

  (I) FORMULA kontrol k1 k2 k3 p

• 7.5360 2.6346 .065 -15.4198 .3478
• 3.7680 2.6346 .616 -11.6518 4.1158

  .0000 2.6346 1.000 -7.8838 7.8838 (J) FORMULA k1 k2 k3 p kontrol k2 k3 p kontrol k1 k3 p kontrol k1 k2 p kontrol k1 k2 k3

  .0000 2.6346 1.000 -7.8838 7.8838

  3.7680 2.6346 .616 -4.1158 11.6518 3.7680 2.6346 .616 -4.1158 11.6518

  3.7680 2.6346 .616 -4.1158 11.6518 7.5360 2.6346 .065 -.3478 15.4198 7.5360 2.6346 .065 -.3478 15.4198

  11.3040* 2.6346 .003 3.4202 19.1878 11.3040* 2.6346 .003 3.4202 19.1878

  3.7680 2.6346 .616 -4.1158 11.6518 7.5360 2.6346 .065 -.3478 15.4198

  Dependent Variable: VOLUME Tukey HSD

  

Multiple Comparisons

• 3.7680 2.6346 .616 -11.6518 4.1158
• 11.3040* 2.6346 .003 -19.1878 -3.4202
• 7.5360 2.6346 .065 -15.4198 .3478
• 3.7680 2.6346 .616 -11.6518 4.1158
• 11.3040* 2.6346 .003 -19.1878 -3.4202
• 7.5360 2.6346 .065 -15.4198 .3478
• 3.7680 2.6346 .616 -11.6518 4.1158

• .

  95% Confidence Interval The mean difference is significant at the .05 level.

  1.2560 1.4861 .913 -3.1911 5.7031 2.5120 1.4861 .462 -1.9351 6.9591 2.5120 1.4861 .462 -1.9351 6.9591

  20 5.521 198.770

  24 Between Groups Within Groups Total Sum of

  Squares df Mean Square F Sig.

  Multiple Comparisons

  Dependent Variable: VOLUME Tukey HSD

  2.5120 1.4861 .462 -1.9351 6.9591 3.7680 1.4861 .122 -.6791 8.2151 5.0240* 1.4861 .022 .5769 9.4711 5.0240* 1.4861 .022 .5769 9.4711

  1.2560 1.4861 .913 -3.1911 5.7031 1.2560 1.4861 .913 -3.1911 5.7031

  Interval for Mean Minimum Maximum ANOVA

  .0000 1.4861 1.000 -4.4471 4.4471

  .0000 1.4861 1.000 -4.4471 4.4471 (J) FORMULA k1 k2 k3 p kontrol k2 k3 p kontrol k1 k3 p kontrol k1 k2 p kontrol k1 k2 k3

  (I) FORMULA kontrol k1 k2 k3 p

  Mean Difference (I-J) Std. Error Sig.

  Lower Bound

  Upper Bound

  VOLUME 88.342 4 22.086 4.000 .015 110.428

  Bound Upper Bound 95% Confidence

  Perhitungan One Way Anova Volume Telapak Kaki Tikus Jam ke-8

  12.56

  

Descriptives

  VOLUME 5 17.5840 2.8085 1.2560 14.0968 21.0712

  12.56

  18.84 5 15.0720 3.4397 1.5383 10.8011 19.3429

  12.56

  18.84 5 13.8160 2.8085 1.2560 10.3288 17.3032

  18.84 5 12.5600 2.565E-16 1.147E-16 12.5600 12.5600

  Std. Deviation Std. Error Lower

  12.56

  12.56 5 12.5600 2.565E-16 1.147E-16 12.5600 12.5600

  12.56

  12.56 25 14.3184 2.8779 .5756 13.1305 15.5063

  12.56

  18.84 kontrol k1 k2 k3 p Total N Mean

• 2.5120 1.4861 .462 -6.9591 1.9351
• 3.7680 1.4861 .122 -8.2151 .6791
• 1.2560 1.4861 .913 -5.7031 3.1911
• 5.0240* 1.4861 .022 -9.4711 -.5769
• 2.5120 1.4861 .462 -6.9591 1.9351
• 1.2560 1.4861 .913 -5.7031 3.1911
• 5.0240* 1.4861 .022 -9.4711 -.5769
• 2.5120 1.4861 .462 -6.9591 1.9351
• 1.2560 1.4861 .913 -5.7031 3.1911
• .

  VOLUME a

  Tukey HSD Subset for alpha = .05 FORMULA N

  1

  2 k3

5 12.5600

p

5 12.5600

k2 5 13.8160 13.8160 k1 5 15.0720 15.0720 kontrol 5 17.5840 Sig. .462 .122

  

Means for groups in homogeneous subsets are displayed.

  a.

  

Uses Harmonic Mean Sample Size = 5.000.

  LAMPIRAN E

PERHITUNGAN ONE WAY ANOVA JUMLAH LEUKOSIT TIKUS

  2.7E+07 4 6797650 10.403 .000

  Mean Square F Sig.

  Sum of Squares df

  Within Groups Total

  1.3E+07 20 653450.0

  LEUKOSIT

  Perhitungan One Way Anova Jumlah Leukosit Tikus Jam ke-0

  Interval for Mean Minimum Maximum ANOVA

  Bound Upper Bound 95% Confidence

  Std. Deviation Std. Error Lower

  25 8504.00 1295.18 259.04 7969.38 9038.62 6600 12050 kontrol k1 k2 k3 p Total N Mean

  5 7480.00 538.05 240.62 6811.92 8148.08 6950 8350 5 8220.00 608.89 272.30 7463.96 8976.04 7500 8900 5 9030.00 680.62 304.38 8184.89 9875.11 8300 9850 5 10260.00 1145.86 512.45 8837.22 11682.78 9200 12050

  

Descriptives

LEUKOSIT 5 7530.00 911.45 407.62 6398.28 8661.72 6600 8950

4.0E+07

24 Between Groups

  a.

  Lower Bound

  Uses Harmonic Mean Sample Size = 5.000.

  3 Subset for alpha = .05 Means for groups in homogeneous subsets are displayed.

  

2

  1

  N

  FORMULA k1 kontrol k2 k3 p Sig.

  5 7480.00 5 7530.00 7530.00 5 8220.00 8220.00

5 9030.00 9030.00

5 10260.00

.606 .056 .155

  LEUKOSIT Tukey HSD a

  95% Confidence Interval The mean difference is significant at the .05 level.

  Upper Bound

  Mean Difference (I-J) Std. Error Sig.

  (I) FORMULA kontrol k1 k2 k3 p

  (J) FORMULA k1 k2 k3 p kontrol k2 k3 p kontrol k1 k3 p kontrol k1 k2 p kontrol k1 k2 k3

• 2730.00* 511.25 .000 -4259.88 -1200.12
• 50.00 511.25 1.000 -1579.88 1479.88

  2730.00* 511.25 .000 1200.12 4259.88 2780.00* 511.25 .000 1250.12 4309.88 2040.00* 511.25 .006 510.12 3569.88 1230.00 511.25 .155 -299.88 2759.88

  810.00 511.25 .524 -719.88 2339.88

  1500.00 511.25 .056 -29.88 3029.88 1550.00* 511.25 .046 20.12 3079.88

  690.00 511.25 .665 -839.88 2219.88 740.00 511.25 .606 -789.88 2269.88

  29.88

  50.00 511.25 1.000 -1479.88 1579.88

  Dependent Variable: LEUKOSIT Tukey HSD

  

Multiple Comparisons

• 690.00 511.25 .665 -2219.88 839.88
• 1500.00 511.25 .056 -3029.88
• 740.00 511.25 .606 -2269.88 789.88
• 1550.00* 511.25 .046 -3079.88 -20.12
• 2780.00* 511.25 .000 -4309.88 -1250.12
• 810.00 511.25 .524 -2339.88 719.88
• 2040.00* 511.25 .006 -3569.88 -510.12
• 1230.00 511.25 .155 -2759.88 299.88
• .
LEUKOSIT

  1.7E+07 20 856950.0

  Squares df Mean Square F Sig.

  Perhitungan One Way Anova Jumlah Leukosit Tikus Jam ke-2

  

Descriptives

LEUKOSIT 5 8210.00 661.82 295.97 7388.25 9031.75 7550 9250

  5 8320.00 789.46 353.06 7339.75 9300.25 7200 9000 5 8850.00 754.16 337.27 7913.59 9786.41 8150 10050 5 9940.00 1018.21 455.36 8675.73 11204.27 8900 11550 5 11090.00 1272.01 568.86 9510.60 12669.40 9750 12900

  25 9282.00 1398.73 279.75 8704.63 9859.37 7200 12900 kontrol k1 k2 k3 p Total N Mean

  Std. Deviation Std. Error Lower

  Bound Upper Bound 95% Confidence

  Interval for Mean Minimum Maximum ANOVA

  3.0E+07 4 7453850 8.698 .000

4.7E+07

  24 Between Groups Within Groups Total Sum of

  Multiple Comparisons Dependent Variable: LEUKOSIT Tukey HSD

  21.97

  k1 k2 k3 p kontrol k2 k3 p kontrol k1 k3 p kontrol k1 k2 p kontrol k1 k2 k3

  (I) FORMULA kontrol k1 k2 k3 p

  Mean Difference (I-J) Std. Error Sig.

  Lower Bound Upper Bound

  95% Confidence Interval The mean difference is significant at the .05 level.

• 110.00 585.47 1.000 -1861.97 1641.97
• 640.00 585.47 .808 -2391.97 111
• 1730.00 585.47 .054 -3481.97
• 2880.00* 585.47 .001 -4631.97 -1128.03 110.00 585.47 1.000 -1641.97 1861.97
• 530.00 585.47 .892 -2281.97 122
• 1620.00 585.47 .079 -3371.97 131.97
• 2770.00* 585.47 .001 -4521.97 -1018.03 640.00 585.47 .808 -1111.97 2391.97 530.00 585.47 .892 -1221.97 2281.97
• 1090.00 585.47 .368 -2841.97 661.97
• 2240.00* 585.47 .008 -3991.97 -488.03 1730.00 585.47 .054 -21.97 3481.97 1620.00 585.47 .079 -131.97 3371.97 1090.00 585.47 .368 -661.97 2841.97
• 1150.00 585.47 .318 -2901.97 601.97 2880.00* 585.47 .001 1128.03 4631.97 2770.00* 585.47 .001 1018.03 4521.97 2240.00* 585.47 .008 488.03 3991.97 1150.00 585.47 .318 -601.97 2901.97 (J) FORMULA
• .

  LEUKOSIT a

  Tukey HSD Subset for alpha = .05 FORMULA N

  1

  2 kontrol 5 8210.00 k1 5 8320.00 k2 5 8850.00 k3 5 9940.00 9940.00 p 5 11090.00 Sig. .054 .318

  Means for groups in homogeneous subsets are displayed.

  a.

  Uses Harmonic Mean Sample Size = 5.000.

  Perhitungan One Way Anova Jumlah Leukosit Tikus Jam ke-4

  

Descriptives

LEUKOSIT 95% Confidence

  Interval for Mean Std. Lower Upper N Mean Deviation Std. Error Bound Bound Minimum Maximum kontrol

  5 9260.00 913.37 408.47 8125.90 10394.10 8200 10500 k1 5 12320.00 2665.66 1192.12 9010.14 15629.86 7900 14450 k2 5 14480.00 1486.86 664.94 12633.82 16326.18 12650 16800 k3 5 14500.00 963.72 430.99 13303.39 15696.61 13150 15500 p 5 14410.00 1614.54 722.05 12405.28 16414.72 11950 16200 Total

  25 12994.00 2575.01 515.00 11931.09 14056.91 7900 16800 ANOVA

  LEUKOSIT Sum of Mean Squares df Square F Sig.

  Between Groups

  1.0E+08

  4

  2.6E+07 9.534 .000 Within Groups

  5.5E+07 20 2737250 Total

  1.6E+08

  24

  a.

  Lower Bound

  Uses Harmonic Mean Sample Size = 5.000.

  2 Subset for alpha = .05 Means for groups in homogeneous subsets are displayed.

  1

  N

  FORMULA kontrol k1 p k2 k3 Sig.

  5 9260.00 5 12320.00 12320.00 5 14410.00 5 14480.00 5 14500.00 .057 .265

  LEUKOSIT Tukey HSD a

  95% Confidence Interval The mean difference is significant at the .05 level.

  Upper Bound

  Mean Difference (I-J) Std. Error Sig.

  (I) FORMULA kontrol k1 k2 k3 p

• 5220.00* 1046.37 .001 -8351.17 -2088.83
• 5240.00* 1046.37 .001 -8371.17 -2108.83
• 5150.00* 1046.37 .001 -8281.17 -2018.83

  5150.00* 1046.37 .001 2018.83 8281.17 2090.00 1046.37 .303 -1041.17 5221.17

  20.00 1046.37 1.000 -3111.17 3151.17 90.00 1046.37 1.000 -3041.17 3221.17

  70.00 1046.37 1.000 -3061.17 3201.17 5240.00* 1046.37 .001 2108.83 8371.17 2180.00 1046.37 .265 -951.17 5311.17

  5220.00* 1046.37 .001 2088.83 8351.17 2160.00 1046.37 .273 -971.17 5291.17

  3060.00 1046.37 .057 -71.17 6191.17

  71.17

  Dependent Variable: LEUKOSIT Tukey HSD

  

Multiple Comparisons

• 3060.00 1046.37 .057 -6191.17
• 2160.00 1046.37 .273 -5291.17 971.17
• 2180.00 1046.37 .265 -5311.17 951.17
• 2090.00 1046.37 .303 -5221.17 1041.17
• 20.00 1046.37 1.000 -3151.17 3111.17
• 70.00 1046.37 1.000 -3201.17 3061.17
• 90.00 1046.37 1.000 -3221.17 3041.17 (J) FORMULA k1 k2 k3 p kontrol k2 k3 p kontrol k1 k3 p kontrol k1 k2 p kontrol k1 k2 k3
• .

  2.3E+08

  Within Groups Total

  Mean Square F Sig.

  Perhitungan One Way Anova Jumlah Leukosit Tikus Jam ke-6

  

Descriptives

LEUKOSIT 5 10340.00 824.17 368.58 9316.66 11363.34 9550 11650

  5 15490.00 601.46 268.98 14743.19 16236.81 14900 16350 5 17970.00 1401.16 626.62 16230.23 19709.77 16350 19650 5 18020.00 1151.41 514.93 16590.33 19449.67 16200 19250 5 16520.00 1917.88 857.70 14138.64 18901.36 13950 18450

  25 15668.00 3108.55 621.71 14384.85 16951.15 9550 19650 kontrol k1 k2 k3 p Total N Mean

  Std. Deviation Std. Error Lower

  Bound Upper Bound 95% Confidence

  Interval for Mean Minimum Maximum ANOVA

  LEUKOSIT

  2.0E+08

  4

  5.0E+07 31.199 .000

  3.2E+07 20 1601650

  Sum of Squares df

24 Between Groups

  Multiple Comparisons

  Dependent Variable: LEUKOSIT Tukey HSD

  5150.00* 800.41 .000 2754.84 7545.16

• 2480.00* 800.41 .040 -4875.16 -84.84
• 2530.00* 800.41 .035 -4925.16 -134.84
• 1030.00 800.41 .702 -3425.16 1365.16

  7630.00* 800.41 .000 5234.84 10025.16 2480.00* 800.41 .040 84.84 4875.16

• 50.00 800.41 1.000 -2445.16 2345.16 1450.00 800.41 .395 -945.16 3845.16 7680.00* 800.41 .000 5284.84 10075.16 2530.00* 800.41 .035 134.84 4925.16

  50.00 800.41 1.000 -2345.16 2445.16 1500.00 800.41 .362 -895.16 3895.16 6180.00* 800.41 .000 3784.84 8575.16 1030.00 800.41 .702 -1365.16 3425.16

  (I) FORMULA kontrol k1 k2 k3 p

  Mean Difference (I-J) Std. Error Sig.

  Lower Bound

  Upper Bound

  95% Confidence Interval The mean difference is significant at the .05 level.

• 5150.00* 800.41 .000 -7545.16 -2754.84
• 7630.00* 800.41 .000 -10025.16 -5234.84
• 7680.00* 800.41 .000 -10075.16 -5284.84
• 6180.00* 800.41 .000 -8575.16 -3784.84
• 1450.00 800.41 .395 -3845.16 945.16
• 1500.00 800.41 .362 -3895.16 895.16 (J) FORMULA k1 k2 k3 p kontrol k2 k3 p kontrol k1 k3 p kontrol k1 k2 p kontrol k1 k2 k3
• .

  LEUKOSIT Tukey HSD a

  Std. Deviation Std. Error Lower

  24 Between Groups Within Groups Total Sum of

  1.1E+08

  3.5E+07 20 1773750

  1.9E+07 10.549 .000

  4

  7.5E+07

  LEUKOSIT

  Interval for Mean Minimum Maximum ANOVA

  Bound Upper Bound 95% Confidence

  25 11146.00 2143.98 428.80 10261.01 12030.99 7200 14800 kontrol k1 k2 k3 p Total N Mean

  5 10340.00 5 15490.00

5 16520.00 16520.00

5 17970.00

5 18020.00

1.000 .702 .362

  5 8390.00 964.62 431.39 7192.26 9587.74 7200 9750 5 10540.00 1037.67 464.06 9251.57 11828.43 8950 11800 5 11420.00 1796.73 803.52 9189.06 13650.94 9400 14100 5 11650.00 1667.71 745.82 9579.27 13720.73 9950 14100

  

Descriptives

LEUKOSIT 5 13730.00 923.04 412.80 12583.90 14876.10 12400 14800

  Perhitungan One Way Anova Jumlah Leukosit Tikus Jam ke-8

  a.

  Uses Harmonic Mean Sample Size = 5.000.

  3 Subset for alpha = .05 Means for groups in homogeneous subsets are displayed.

  2

  1

  N

  FORMULA kontrol k1 p k2 k3 Sig.

  Squares df Mean Square F Sig. a.

  Uses Harmonic Mean Sample Size = 5.000.

  Upper Bound

  3 Subset for alpha = .05 Means for groups in homogeneous subsets are displayed.

  

2

  1

  N

  FORMULA k1 k2 k3 p kontrol Sig.

  5 8390.00 5 10540.00 10540.00

5 11420.00 11420.00

5 11650.00 11650.00

5 13730.00

.118 .684 .082

  LEUKOSIT Tukey HSD a

  95% Confidence Interval The mean difference is significant at the .05 level.

  Lower Bound

  Mean Difference (I-J) Std. Error Sig.

  (I) FORMULA kontrol k1 k2 k3 p

• 880.00 842.32 .832 -3400.55 1640.55
• 1110.00 842.32 .684 -3630.55 1410.55
• 2310.00 842.32 .082 -4830.55 210.55

  230.00 842.32 .999 -2290.55 2750.55 (J) FORMULA k1 k2 k3 p kontrol k2 k3 p kontrol k1 k3 p kontrol k1 k2 p kontrol k1 k2 k3

  3260.00* 842.32 .008 739.45 5780.55 1110.00 842.32 .684 -1410.55 3630.55

  3030.00* 842.32 .014 509.45 5550.55 880.00 842.32 .832 -1640.55 3400.55

  2150.00 842.32 .118 -370.55 4670.55

  5340.00* 842.32 .000 2819.45 7860.55 3190.00* 842.32 .009 669.45 5710.55 2310.00 842.32 .082 -210.55 4830.55 2080.00 842.32 .138 -440.55 4600.55

  Dependent Variable: LEUKOSIT Tukey HSD

  

Multiple Comparisons

• 5340.00* 842.32 .000 -7860.55 -2819.45
• 2150.00 842.32 .118 -4670.55 370.55
• 3030.00* 842.32 .014 -5550.55 -509.45
• 3260.00* 842.32 .008 -5780.55 -739.45
• 3190.00* 842.32 .009 -5710.55 -669.45
• 230.00 842.32 .999 -2750.55 2290.55
• 2080.00 842.32 .138 -4600.55 440.55
• .

  

LAMPIRAN F

PERHITUNGAN SUSUT PENGERINGAN, PENETAPAN KADAR ABU

  SIMPLISIA, KADAR SENYAWA YANG LARUT DALAM ETANOL,

DAN KADAR AIR

  Perhitungan Susut Pengeringan Replikasi Hasil Susut Pengeringan 1 8,29

  2 8,11 3 8,38 Rerata ± SD 8,26 ± 0,14

  Perhitungan Penetapan Kadar Abu Simplisia (berat konstan krus - abu) (berat konstan krus kosong)

• Kadar abu

  100 % =

  × berat serbuk Berat Berat konstan Berat

  Kadar abu Replikasi serbuk krus kosong konstan krus

  (%) (gram) (gram) + abu (gram) 1 2,0066 21,5941 21,7032 5,44

  2 2,0085 21,6042 21,6997 4,75 3 2,0098 21,5536 21,6588 5,23 Rerata ± SD 5,14 ± 0,35 Penetapan Kadar Senyawa yang Larut dalam Etanol

• ( berat konstan cawan serbuk) (berat cawan)

• Kadar senyawa larut etanol 100 %

  = × berat serbuk

  No Berat Berat konstan Berat konstan Kadar serbuk cawan (gram) cawan + serbuk senyawa larut (gram) (gram) etanol (%) 1 5,0037 67,3145 67,4132 3,97%

  2 5,0068 72,3618 72,5364 3,48% 3 5,0073 62,0231 62,2164 3,86% Rerata ± SD 3,77 ± 0,25

  Penetapan Kadar Air Replikasi Kadar Air 1 4,29

  2 4,11 3 3,87 Rerata ± SD 4,09 ± 0,21