Pengaruh Penambahan Ekstrak Etanol Daun Sirsak (Annona muricata L.) Terhadap Nilai SPF Krim Tabir Surya Kombinasi Avobenson dan Oktil Metoksisinamat

PENGARUH PENAMBAHAN EKSTRAK ETANOL DAUN SIRSAK
(Annona muricata L.) TERHADAP NILAI SPF
KRIM TABIR SURYA KOMBINASI
AVOBENSON DAN OKTIL METOKSISINAMAT
ABSTRAK
Paparan sinar matahari yang disebabkan sinar ultraviolet berdampak buruk
pada kulit, berupa eritema, sunburn, pigmentasi dan penyakit kanker kulit. Untuk
melindungi kulit dari efek buruk tersebut, salah satunya digunakan tabir surya
yang diformulasikan dalam sediaan krim. Daun sirsak berperan sebagai
antioksidan yang terdapat pada senyawa fenol dan flavonoid yang memiliki
potensi fotoproteksi karena dapat menyerap sinar UV. Tujuan penelitian ini
adalah untuk mengevaluasi pengaruh ekstrak etanol daun sirsak terhadap
efektivitas krim tabir surya kombinasi avobenson dan oktil metoksisinamat,
dengan mengukur nilai SPF (Sun protection Factor).
Pada penelitian ini, pembuatan ekstrak etanol daun sirsak dilakukan
dengan cara perkolasi. Krim tabir surya kombinasi avobenson dan oktil
metoksisinamat diformulasikan dengan penambahan ekstrak etanol daun sirsak
dengan konsentrasi 4% (FI), 6% (FII), 8% (FIII) dan 10% (FIV). Evaluasi sediaan
krim tabir surya meliputi organoleptis, homogenitas, tipe emulsi, pH, stabilitas,
iritasi kulit, dan penentuan nilai SPF krim tabir surya secara in vitro menggunakan
spektrofotometer UV Visible.

Penelitian menunjukkan bahwa semua sediaan krim tabir surya ekstrak
etanol daun sirsak homogen dengan tipe emulsi m/a, rentang pH pada kisaran 5,7
- 6,3, tidak mengiritasi, dan stabil selama 12 minggu penyimpanan pada suhu
kamar. Nilai SPF meningkat dengan meningkatnya konsentrasi ekstrak etanol
daun sirsak. Nilai SPF basis krim, blanko dan krim dengan penambahan ekstrak
etanol daun sirsak 4% (FI), 6% (FII), 8% (FIII) dan 10% (FIV) berturut-turut
adalah 0,39; 15,85; 16,96; 19,46; 20,99 dan 23,49. Hasil analisis secara statistik
menunjukkan peningkatan nilai SPF ini memiliki perbedaan yang signifikan (p <
0.05). Dapat disimpulkan bahwa ektrak etanol daun sirsak dapat meningkatkan
nilai SPF tabir surya kombinasi avobenson dan oktil metoksisinamat.
Kata kunci: ekstrak etanol daun sirsak, avobenson, oktil metoksisinamat, SPF, tabir
surya.

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Universitas Sumatera Utara

THE EFFECT OF ETHANOL EXTRACT LEAVES OF SOURSOP
(Annona muricata L.) ON SPF VALUE OF
AVOBENZONE AND OCTYL METHOXYCINNAMATE
COMBINATION AS SUNSCREEN CREAM

ABSTRACT
Sun exprosure (ultraviolet radiation) which is caused by ultraviolet rays
have a negative impact on the skin, such as erythema, sunburn, pigmentation and
skin cancer. In order to protect skin from that effect, sunscreen formulated in
cream can be used. Soursoup leaves act as antioxidants contain phenolic and
flavonoid substance that have the potential photoprotection because of their UV
absorbing. The purpose of this study was to evaluate the influence of ethanol
extract leaves of soursop on effectiveness of sunscreen cream containing a
combination of avobenzone and octyl methoxycinnamate, with measurement of
SPF (Sun Protection Factor).
In this study, the ethanol extract leaves of soursop leaves were done by
percolation. The suncreen cream of avobenzone and octyl methoxycinnamate
combination was formulated with addition of Soursop leaves extract at 4% (FI),
6% (FII), 8% (FIII) dan 10% (FIV). Evaluations conducted on organeleptic,
homogenity, emulsion type, pH, stability, skin irritation, and SPF value of
sunscreens was determined by in vitro method using UV Visible
spectrophotometer.
The study showed that all the samples of sunscreen cream ethanol extract
leaves of soursop was homogeneous with emulsion type m/a, in range of 5.7 - 6.3
pH range, non-irritating, and stable dosage during 12 weeks of storage at room

temperature. The research showed that SPF value increased by increasing the
Soursop leaves extract concentration. The SPF value of cream base, blank, and
cream with extract addition 4% (FI), 6% (FII), 8% (FIII) and 10% (FIV) were
0.39; 15.85; 16.96; 19.46; 20.99 dan 23.49. The results of statistical analysis
showed significant differences (p < 0.05).It can be concluded that ethanol extract
leaves of soursop can increase that sunscreen cream SPF value of combination
avobenzone and octyl methoxycinnamate.
Keywords: ethanol extract leaves of soursop,
avobenzone,
methoxycinnamate, SPF (Sun Protection Factor), sunscreen.

octyl

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Universitas Sumatera Utara