1.7. Novelties
The studies on the use selected biomarkers in terms of in vivo and in situ applications proposed new findings.
1. The OP pesticides are acknowledged as anticholinesterase of living organisms from vertebrate to invertebrate. In invertebrate particularly in
marine mussel many studies were conducted to recognize the effect of pesticides on ChE activity of the mussels. However, the extension effect
of the pesticides on higher biological integrity such as siphoning activity that have conceptually closed relate to nervous system has been not
studied yet in terms of the correlation between the ChE activity inhibition of different organs of blue mussel and the siphoning rate. One part of the
studies revealed that the transformation of inhibition of ChE activity induced by the pesticide in innervated organs to inhibition of the siphoning
activity of blue mussel was observed. 2. The requirement for using ChE activity as a biomarker in new eco-sentinel
organism is characterization of ChEs enzyme properties of the studied animal. Prior to application of the ChE activity from P. viridis in hot spot
biomonitoring, the characterization of the ChEs of the indigenous sentinel organism, P. viridis was conducted. The study suggested that ChEs of P.
viridis can be classified as a typical acetylcholinesterase AChE and an
atypical butyrilcholinesetase BuChE.
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II. THE USE OF SELECTED BIOMARKERS, PHAGOCYTIC AND CHOLINESTERASE ACTIVITIES, TO DETECT THE
EFFECTS OF DIMETHOATE ON MARINE MUSSEL Mytilus
edulis
2.1.. Abstract
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