disruption which was pursued by severe damages when mussels were exposed to the higher concentrations. The hypothesis of the initial damage was probably also
strengthened by the fact that inhibition of the ChE activity of the mussel gills about 23 compared to the control when mussels were exposed to dimethoate at
the lowest level concentration. Therefore, it could be suggested that the threshold of dimethoate effects on the phagocyotis and the ChE activity of the mussels
probably occured at concentration below 31.50 µgl. Finally, the results showed that the selected biomarkers were useful tools
for detecting the neuro-immune effects of dimethoate on blue mussels in the laboratory scale as far as the hormesis dose-response paradigm was considered
along with the dose-dependent response paradigm. This paradigm provide a worthy outlook to move forward scientifically from a traditional dose-dependent
to others realistic phenomena which appear in the laboratory experiments commonly Calabrese and Baldwin 2003.
Acknowledgement
This study was supported by DAAD Deutscher Akademischer Austausch DientsGerman Academic Exchange Service. The authors wish to thank Dr.
Eckehard Unruh and Birgit Fischer from Technical University of Berlin for the constructive advices and Birgit Hüssel from Alfred Wagner Institute for the
organization of blue mussel, M. edulis.
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III. EVALUATION ON SENSITIVITY OF SELECTED BIOMARKERS, CHOLINESTERASE ACTIVITY AND
SIPHONING RATE OF Mytilus edulis TO TRICHLORFON
3.1. Abstract
