232 PROCEEDING BOOK
The 2
nd
International Conference on Health Science 2015
Table 6. Frequency Distribution of Respondents’ Creatinine Levels
No. Creatinine Level Mean
± SEM SD
Minimum value
Maximum value
1. Respondents in general
11,04 ± 1,06
5,80 3,80
27,50
2. Age
30-45 tahun
46-59 tahun
60-80 tahun
10,88 ± 1,44
12,61 ± 2,03
7,31 ± 1,16
4,78 6,73
3,06 4,80
7,10 3,80
20,60 27,50
10,6
3. Sex
Male Female
10,25 ± 1,47
12,08 ± 1,52
6,08 5,48
3,80 4,80
27,50 21,50
4. Diabetes Mellitus status
CRF without DM CRF with DM
13,29 ± 1,39
7,16 ± 0,70
6,05 2,33
4,80 3,80
27,50 11,00
Table 7. Difference test on BUN and Creatinine Levels
No. Variables Difference test
p value Interpretation
1. BUN Mann whitney test
0,590 Not signifi cantly different
2. Creatinine Independent t-test
0,003 Signifi cantly different
DISCUSSION
Chronic renal failure CRF is a condition of kidney damage that can be seen bythe results of urination, radiology and histology examination. CRF diagnosis is made when a
patient has a glomerular fi ltration rate GFR of less than 60 mL min 1.73 m² in the same period for more than three months.
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End-stage renal disease ESDR, or terminal renal failure, is defi ned as kidney damage characterized by decreased GFR 15 mL min 1.73
m², as well as abnormalities examination of serum BUN.
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Age as A Risk Factor of CRF
Chronic renal failure CRF is a disease that can be suffered by all age ranges, either children, teenagers or the elderly. This is in line with the results listed in Table 1 which point
out that respondents with CRF can be found in young adults 3.30, middle age 36.70, older adults 36.70, and the elderly 23.30.
Kidney failure can occur in all age ranges withvarious causes.
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At a young age, failure can result from chronic dehydration and nephrotoxic substances. Consumption of food or
beverages containing nephrotoxic substances will accelerate the destruction of kidney cells. At the age of older adults and the elderly, the growing ability of kidney cells anatomically
decline and the deterioration of the kidney cell function may also start to occur.
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Most respondents 96.70 in this study was 40 years old and above. The results correspond Lindeman and Preuss’ theory 1994, which states that the kidney function will
decline progressively from the age of 40 years.
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Kidneys will experience changes in structure and function along withhuman aging proccess. According to Chadijah and Wirawanni 2012,
renal function begins to decline by the age of 40 years and at the age of 60 years old the function remainshalf of the capacity function at the age of 40 years, due to the physiological