epi surveillance review tls 2015
Joint National/International Expanded
Programme on Immunization and
Vaccine-Preventable Disease
Surveillance Review
Democratic Republic of Timor-Leste, 1-13 March 2015
i
Joint National/International Expanded Programme on Immunization and Vaccine-Preventable Disease Surveillance Review, Democratic
Republic of Timor-Leste
© World Health Organization 2017
Some rights reserved. This work is available under the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 IGO licence
(CC BY-NC-SA 3.0 IGO; https://creativecommons.org/licenses/by-nc-sa/3.0/igo).
Under the terms of this licence, you may copy, redistribute and adapt the work for non-commercial purposes, provided the work is
appropriately cited, as indicated below. In any use of this work, there should be no suggestion that WHO endorses any specific organization,
products or services. The use of the WHO logo is not permitted. If you adapt the work, then you must license your work under the same or
equivalent Creative Commons licence. If you create a translation of this work, you should add the following disclaimer along with the
suggested citation: “This translation was not created by the World Health Organization (WHO). WHO is not responsible for the content or
accuracy of this translation. The original English edition shall be the binding and authentic edition”.
Any mediation relating to disputes arising under the licence shall be conducted in accordance with the mediation rules of the World
Intellectual Property Organization.
Suggested citation. Joint National/International Expanded Programme on Immunization and Vaccine-Preventable Disease Surveillance
Review, Democratic Republic of Timor-Leste, New Delhi: World Health Organization, Regional Office for South-East Asia; 2017. Licence:
CC BY-NC-SA 3.0 IGO.
Cataloguing-in-Publication (CIP) data. CIP data are available at http://apps.who.int/iris.
Sales, rights and licensing. To purchase WHO publications, see http://apps.who.int/bookorders. To submit requests for commercial use and
queries on rights and licensing, see http://www.who.int/about/licensing.
Third-party materials. If you wish to reuse material from this work that is attributed to a third party, such as tables, figures or images, it is
your responsibility to determine whether permission is needed for that reuse and to obtain permission from the copyright holder. The risk of
claims resulting from infringement of any third-party-owned component in the work rests solely with the user.
General disclaimers. The designations employed and the presentation of the material in this publication do not imply the expression of any
opinion whatsoever on the part of WHO concerning the legal status of any country, territory, city or area or of its authorities, or concerning
the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not
yet be full agreement. The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or
recommended by WHO in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of
proprietary products are distinguished by initial capital letters.
All reasonable precautions have been taken by WHO to verify the information contained in this publication. However, the published material
is being distributed without warranty of any kind, either expressed or implied. The responsibility for the interpretation and use of the material
lies with the reader. In no event shall WHO be liable for damages arising from its use.
ii
Contents
Abbreviations and acronyms............................................................................................................................... v
1
Introduction .................................................................................................................................................... 1
2
Background ..................................................................................................................................................... 1
3
Objectives and methodology ................................................................................................................... 4
3.1 Objectives .............................................................................................................................................. 4
3.2 Methodology........................................................................................................................................ 5
4
Findings and recommendations .............................................................................................................. 5
4.1 Policies, strategies and service delivery ..................................................................................... 6
4.1.1
Major achievements and issues identified .........................................................................6
4.1.2
Recommendations.......................................................................................................................7
4.2 Immunization supply chain management................................................................................. 7
4.2.1
Major achievements and issues identified .........................................................................7
4.2.2
Recommendations.......................................................................................................................8
4.3 Programme monitoring and use of data ................................................................................... 8
4.3.1
Major achievements and issues identified .........................................................................8
4.3.2
Recommendations.................................................................................................................... 10
4.4 New vaccine introduction..............................................................................................................10
4.4.1
Major achievements and issues identified ...................................................................... 10
4.4.2
Recommendations.................................................................................................................... 10
4.5 Communication and social mobilization .................................................................................11
4.5.1
Major achievements and issues identified ...................................................................... 11
4.5.2
Recommendations.................................................................................................................... 11
4.6 VPD surveillance................................................................................................................................11
4.6.1
Major achievements and major issues identified ......................................................... 11
4.6.2
Recommendations.................................................................................................................... 14
4.7 Disease elimination and control .................................................................................................15
4.7.1
Polio eradication ....................................................................................................................... 15
4.7.1.1 Major achievements and major issues identified…………………………………………. 16
4.7.1.2 Recommendations………………………………………………………………………………………….17
4.7.2
Measles elimination and rubella/CRS control ................................................................ 17
4.7.2.1 Major achievements and major issues identified………………………….………………..18
4.7.2.2 Recommendations……………………………………………………………………….…………………19
4.7.3
Maternal and neonatal tetanus elimination ................................................................... 19
4.7.3.1 Major achievements and major issues identified…………………………………….……..19
4.7.3.2 Recommendations……………………………………………………………………….…………………21
4.8 Healthcare system
.............................................................................................22
4.8.1
Major achievements and issues identified ...................................................................... 23
4.8.2
Recommendations.................................................................................................................... 24
iii
5
References .....................................................................................................................................................26
6
Annexes ..........................................................................................................................................................27
6.1 Participants and team members .................................................................................................27
6.2 Team members and sites visited ................................................................................................29
6.3 List of background documents reviewed ................................................................................32
6.4 Municipal reports .............................................................................................................................34
iv
Abbreviations and acronyms
AEFI
adverse events following immunization
ANC
antenatal care
AFP
acute flaccid paralysis
BCG
Bacillus Calmette-Guerin (tuberculosis) vaccine
bOPV
bivalent OPV
BSP
package of basic services
CHC
community health centre
CRS
congenital rubella syndrome
cVDPV
circulating vaccine-derived poliovirus
DHIS
District Health Information Software
DHS
Demographic and Health Survey
DPHO
district public health office
DT
diphtheria tetanus toxoids, paediatric formulation
DTP
diphtheria-tetanus toxoids and pertussis vaccine
DTP1
first dose of DTP
DTP3
third dose of DTP
DHO
district health office
EPI
Expanded Programme on Immunization
EVM
effective vaccine management
FHR
family health register
GVAP
Global Vaccine Action Plan
HDI
Human Development Index
HepB
hepatitis B vaccine
HSS
Healthy System Strengthening
Hib
Haemophilus influenzae type b
v
HMIS
Health Management Information System
HP
health post
IPV
inactivated polio vaccine
India
the Republic of India
Indonesia
the Republic of Indonesia
MCV1
the first dose of measles-containing vaccine
MHO
municipal health office
MNT
maternal and neonatal tetanus
MNTE
maternal and neonatal tetanus elimination
MoH
Ministry of Health
MPHO
municipal public health office
MR
measles-rubella vaccine
MR1
first dose of MR
MR2
second dose of MR
NCCPE
National Certification Committee for Polio Eradication
NT
neonatal tetanus
OPV
oral polio vaccine
OPV2
OPV type 2
OPV3
third dose of OPV
PHC
primary healthcare
PSF
promotor saude familiar (family health promoter)
PV
poliovirus
RCCPE
Regional Certification Commission for Polio Eradication
RI
routine immunization
SEAR
South-East Asia Region
SEARO
(WHO’s) Regional Office for South-East Asia
SIA
supplementary immunization activity
vi
SOPs
standard operating procedures
Td
tetanus and diphtheria vaccine, adult/adolescent formulation
tOPV
trivalent OPV
Timor-Leste
the Democratic Republic of Timor-Leste
TT
tetanus toxoid
TT2+
second and subsequent doses of tetanus toxoid
UNICEF
United Nations Children’s Fund
VAPP
vaccine-associated paralytic polio
VPD
vaccine-preventable disease
VVM
vaccine vial monitor
WHA
World Health Assembly
WHO
World Health Organization
WPV
wild poliovirus
WPV1
WPV type 1
WPV2
WPV type 2
WPV3
WPV type 3
WRA
women of reproductive age
vii
Acknowledgements
We would like to express our sincere gratitude and appreciation to Mr Jose dos Reis Magno,
General Director of the Ministry of Health of the Democratic Republic of Timor-Leste (MoH);
Mr Marcelo Amaral, National Director of the Directorate of Finance and Procurement
Management, MoH; Mr Carlitos Correia Freitas, National Director of the Public Health
Directorate, MoH; Dr Inesh Teodora Almeida da Silva, Director of Services of Diseases
Control, MoH; Ms Isabel Maria Gomes, Director of Services of Community Health, MoH; and
Dr Virna Martins Sam, President of the National Certification Committee for Polio Eradication.
We would also like to thank Dr Rajesh Panav, Representative of the World Health
Organization (WHO) in the Democratic Republic of Timor-Leste; Ms Desiree M. Jongsma,
Representative of the United Nations Children’s Fund (UNICEF) in the Democratic Republic of
Timor-Leste; and Dr Teodulo Clemente de J. Ximenes of the United States Agency for
International Development.
Our special thanks go to the Maternal and Child Health and the Surveillance Departments of
the MoH, and to the WHO and UNICEF teams for their continuous contributions throughout
the review.
viii
1
Introduction
The Sixty-fifth World Health Assembly in May 2012 endorsed The Global Vaccine
Action Plan (GVAP) based on an extensive consultation with countries and multiple
stakeholders. In addition to articulating a global vision for immunization and outlining
key strategies, the GVAP proposes five key goals for the Decade of Vaccines (2011–
2020): (1) to achieve a world free of polio; (2) to meet vaccination coverage targets; (3)
to reduce child mortality; (4) to meet global and regional elimination targets; and (5)
to develop and introduce new vaccines. Each Regional Member State is expected to
further define specific targets and develop and implement action plans to advance
the global goals. Through the Regional strategic plan and other initiatives, the World
Health Organization’s (WHO’s) Regional Office for South-East Asia (SEARO) has
identified specific targets for its Member States. Due to the commitment of national
Expanded Programmes on Immunization (EPIs) and multiple partners, the Region has
made significant progress towards achieving these goals, as exemplified by the
certification of the Region as polio-free in March 2014 and by setting the goal to
eliminate measles and control rubella and congenital rubella syndrome (CRS) by 2020.
In addition, all countries of the South-East Asia Region (SEAR) have certified validation
of maternal and neonatal tetanus elimination (MNTE) except the Republic of
Indonesia (Indonesia) and the Republic of India in which MNTE remains to be
validated in a few provinces or states. However, as noted in the GVAP, sustaining
these achievements and meeting the current global and Regional objectives and
targets will require committed country ownership, ensuring comprehensive and
equitable vaccination coverage, sustainable health systems, and innovation to address
new challenges as they arise.
Periodically reviewing how each country is meeting these requirements not only
provides insight into the status of the national immunization programme (NIP) , but
also allows best practices to be shared with other national EPIs . A comprehensive
review becomes even more important in the context of large migration and crossborder movements. The last joint national and international review of the Democratic
Republic of Timor-Leste’s (Timor-Leste’s) EPI by the MoH and WHO was conducted in
2008 with a follow-up review in 2010. The current review was conducted from 1–13
March 2015 and provided the opportunity to objectively assess the progress and
current status of the EPI and vaccine-preventable disease (VPD) surveillance
programme as well as to provide recommendations for addressing the challenges
faced in meeting national, Regional and global immunization goals and targets.
2.
Background
Timor-Leste is a country of 15 410 km2, with an estimated total population of
1 212 110 and 40 351 children aged
Programme on Immunization and
Vaccine-Preventable Disease
Surveillance Review
Democratic Republic of Timor-Leste, 1-13 March 2015
i
Joint National/International Expanded Programme on Immunization and Vaccine-Preventable Disease Surveillance Review, Democratic
Republic of Timor-Leste
© World Health Organization 2017
Some rights reserved. This work is available under the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 IGO licence
(CC BY-NC-SA 3.0 IGO; https://creativecommons.org/licenses/by-nc-sa/3.0/igo).
Under the terms of this licence, you may copy, redistribute and adapt the work for non-commercial purposes, provided the work is
appropriately cited, as indicated below. In any use of this work, there should be no suggestion that WHO endorses any specific organization,
products or services. The use of the WHO logo is not permitted. If you adapt the work, then you must license your work under the same or
equivalent Creative Commons licence. If you create a translation of this work, you should add the following disclaimer along with the
suggested citation: “This translation was not created by the World Health Organization (WHO). WHO is not responsible for the content or
accuracy of this translation. The original English edition shall be the binding and authentic edition”.
Any mediation relating to disputes arising under the licence shall be conducted in accordance with the mediation rules of the World
Intellectual Property Organization.
Suggested citation. Joint National/International Expanded Programme on Immunization and Vaccine-Preventable Disease Surveillance
Review, Democratic Republic of Timor-Leste, New Delhi: World Health Organization, Regional Office for South-East Asia; 2017. Licence:
CC BY-NC-SA 3.0 IGO.
Cataloguing-in-Publication (CIP) data. CIP data are available at http://apps.who.int/iris.
Sales, rights and licensing. To purchase WHO publications, see http://apps.who.int/bookorders. To submit requests for commercial use and
queries on rights and licensing, see http://www.who.int/about/licensing.
Third-party materials. If you wish to reuse material from this work that is attributed to a third party, such as tables, figures or images, it is
your responsibility to determine whether permission is needed for that reuse and to obtain permission from the copyright holder. The risk of
claims resulting from infringement of any third-party-owned component in the work rests solely with the user.
General disclaimers. The designations employed and the presentation of the material in this publication do not imply the expression of any
opinion whatsoever on the part of WHO concerning the legal status of any country, territory, city or area or of its authorities, or concerning
the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not
yet be full agreement. The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or
recommended by WHO in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of
proprietary products are distinguished by initial capital letters.
All reasonable precautions have been taken by WHO to verify the information contained in this publication. However, the published material
is being distributed without warranty of any kind, either expressed or implied. The responsibility for the interpretation and use of the material
lies with the reader. In no event shall WHO be liable for damages arising from its use.
ii
Contents
Abbreviations and acronyms............................................................................................................................... v
1
Introduction .................................................................................................................................................... 1
2
Background ..................................................................................................................................................... 1
3
Objectives and methodology ................................................................................................................... 4
3.1 Objectives .............................................................................................................................................. 4
3.2 Methodology........................................................................................................................................ 5
4
Findings and recommendations .............................................................................................................. 5
4.1 Policies, strategies and service delivery ..................................................................................... 6
4.1.1
Major achievements and issues identified .........................................................................6
4.1.2
Recommendations.......................................................................................................................7
4.2 Immunization supply chain management................................................................................. 7
4.2.1
Major achievements and issues identified .........................................................................7
4.2.2
Recommendations.......................................................................................................................8
4.3 Programme monitoring and use of data ................................................................................... 8
4.3.1
Major achievements and issues identified .........................................................................8
4.3.2
Recommendations.................................................................................................................... 10
4.4 New vaccine introduction..............................................................................................................10
4.4.1
Major achievements and issues identified ...................................................................... 10
4.4.2
Recommendations.................................................................................................................... 10
4.5 Communication and social mobilization .................................................................................11
4.5.1
Major achievements and issues identified ...................................................................... 11
4.5.2
Recommendations.................................................................................................................... 11
4.6 VPD surveillance................................................................................................................................11
4.6.1
Major achievements and major issues identified ......................................................... 11
4.6.2
Recommendations.................................................................................................................... 14
4.7 Disease elimination and control .................................................................................................15
4.7.1
Polio eradication ....................................................................................................................... 15
4.7.1.1 Major achievements and major issues identified…………………………………………. 16
4.7.1.2 Recommendations………………………………………………………………………………………….17
4.7.2
Measles elimination and rubella/CRS control ................................................................ 17
4.7.2.1 Major achievements and major issues identified………………………….………………..18
4.7.2.2 Recommendations……………………………………………………………………….…………………19
4.7.3
Maternal and neonatal tetanus elimination ................................................................... 19
4.7.3.1 Major achievements and major issues identified…………………………………….……..19
4.7.3.2 Recommendations……………………………………………………………………….…………………21
4.8 Healthcare system
.............................................................................................22
4.8.1
Major achievements and issues identified ...................................................................... 23
4.8.2
Recommendations.................................................................................................................... 24
iii
5
References .....................................................................................................................................................26
6
Annexes ..........................................................................................................................................................27
6.1 Participants and team members .................................................................................................27
6.2 Team members and sites visited ................................................................................................29
6.3 List of background documents reviewed ................................................................................32
6.4 Municipal reports .............................................................................................................................34
iv
Abbreviations and acronyms
AEFI
adverse events following immunization
ANC
antenatal care
AFP
acute flaccid paralysis
BCG
Bacillus Calmette-Guerin (tuberculosis) vaccine
bOPV
bivalent OPV
BSP
package of basic services
CHC
community health centre
CRS
congenital rubella syndrome
cVDPV
circulating vaccine-derived poliovirus
DHIS
District Health Information Software
DHS
Demographic and Health Survey
DPHO
district public health office
DT
diphtheria tetanus toxoids, paediatric formulation
DTP
diphtheria-tetanus toxoids and pertussis vaccine
DTP1
first dose of DTP
DTP3
third dose of DTP
DHO
district health office
EPI
Expanded Programme on Immunization
EVM
effective vaccine management
FHR
family health register
GVAP
Global Vaccine Action Plan
HDI
Human Development Index
HepB
hepatitis B vaccine
HSS
Healthy System Strengthening
Hib
Haemophilus influenzae type b
v
HMIS
Health Management Information System
HP
health post
IPV
inactivated polio vaccine
India
the Republic of India
Indonesia
the Republic of Indonesia
MCV1
the first dose of measles-containing vaccine
MHO
municipal health office
MNT
maternal and neonatal tetanus
MNTE
maternal and neonatal tetanus elimination
MoH
Ministry of Health
MPHO
municipal public health office
MR
measles-rubella vaccine
MR1
first dose of MR
MR2
second dose of MR
NCCPE
National Certification Committee for Polio Eradication
NT
neonatal tetanus
OPV
oral polio vaccine
OPV2
OPV type 2
OPV3
third dose of OPV
PHC
primary healthcare
PSF
promotor saude familiar (family health promoter)
PV
poliovirus
RCCPE
Regional Certification Commission for Polio Eradication
RI
routine immunization
SEAR
South-East Asia Region
SEARO
(WHO’s) Regional Office for South-East Asia
SIA
supplementary immunization activity
vi
SOPs
standard operating procedures
Td
tetanus and diphtheria vaccine, adult/adolescent formulation
tOPV
trivalent OPV
Timor-Leste
the Democratic Republic of Timor-Leste
TT
tetanus toxoid
TT2+
second and subsequent doses of tetanus toxoid
UNICEF
United Nations Children’s Fund
VAPP
vaccine-associated paralytic polio
VPD
vaccine-preventable disease
VVM
vaccine vial monitor
WHA
World Health Assembly
WHO
World Health Organization
WPV
wild poliovirus
WPV1
WPV type 1
WPV2
WPV type 2
WPV3
WPV type 3
WRA
women of reproductive age
vii
Acknowledgements
We would like to express our sincere gratitude and appreciation to Mr Jose dos Reis Magno,
General Director of the Ministry of Health of the Democratic Republic of Timor-Leste (MoH);
Mr Marcelo Amaral, National Director of the Directorate of Finance and Procurement
Management, MoH; Mr Carlitos Correia Freitas, National Director of the Public Health
Directorate, MoH; Dr Inesh Teodora Almeida da Silva, Director of Services of Diseases
Control, MoH; Ms Isabel Maria Gomes, Director of Services of Community Health, MoH; and
Dr Virna Martins Sam, President of the National Certification Committee for Polio Eradication.
We would also like to thank Dr Rajesh Panav, Representative of the World Health
Organization (WHO) in the Democratic Republic of Timor-Leste; Ms Desiree M. Jongsma,
Representative of the United Nations Children’s Fund (UNICEF) in the Democratic Republic of
Timor-Leste; and Dr Teodulo Clemente de J. Ximenes of the United States Agency for
International Development.
Our special thanks go to the Maternal and Child Health and the Surveillance Departments of
the MoH, and to the WHO and UNICEF teams for their continuous contributions throughout
the review.
viii
1
Introduction
The Sixty-fifth World Health Assembly in May 2012 endorsed The Global Vaccine
Action Plan (GVAP) based on an extensive consultation with countries and multiple
stakeholders. In addition to articulating a global vision for immunization and outlining
key strategies, the GVAP proposes five key goals for the Decade of Vaccines (2011–
2020): (1) to achieve a world free of polio; (2) to meet vaccination coverage targets; (3)
to reduce child mortality; (4) to meet global and regional elimination targets; and (5)
to develop and introduce new vaccines. Each Regional Member State is expected to
further define specific targets and develop and implement action plans to advance
the global goals. Through the Regional strategic plan and other initiatives, the World
Health Organization’s (WHO’s) Regional Office for South-East Asia (SEARO) has
identified specific targets for its Member States. Due to the commitment of national
Expanded Programmes on Immunization (EPIs) and multiple partners, the Region has
made significant progress towards achieving these goals, as exemplified by the
certification of the Region as polio-free in March 2014 and by setting the goal to
eliminate measles and control rubella and congenital rubella syndrome (CRS) by 2020.
In addition, all countries of the South-East Asia Region (SEAR) have certified validation
of maternal and neonatal tetanus elimination (MNTE) except the Republic of
Indonesia (Indonesia) and the Republic of India in which MNTE remains to be
validated in a few provinces or states. However, as noted in the GVAP, sustaining
these achievements and meeting the current global and Regional objectives and
targets will require committed country ownership, ensuring comprehensive and
equitable vaccination coverage, sustainable health systems, and innovation to address
new challenges as they arise.
Periodically reviewing how each country is meeting these requirements not only
provides insight into the status of the national immunization programme (NIP) , but
also allows best practices to be shared with other national EPIs . A comprehensive
review becomes even more important in the context of large migration and crossborder movements. The last joint national and international review of the Democratic
Republic of Timor-Leste’s (Timor-Leste’s) EPI by the MoH and WHO was conducted in
2008 with a follow-up review in 2010. The current review was conducted from 1–13
March 2015 and provided the opportunity to objectively assess the progress and
current status of the EPI and vaccine-preventable disease (VPD) surveillance
programme as well as to provide recommendations for addressing the challenges
faced in meeting national, Regional and global immunization goals and targets.
2.
Background
Timor-Leste is a country of 15 410 km2, with an estimated total population of
1 212 110 and 40 351 children aged