Perbandingan Ekspresi Kiss 1 Pada Tumor Ganas Ovarium Tipe Epitel Dengan Tumor Jinak Ovarium Tipe Epitel

62

Hasil Pemeriksaan KiSS1; Tumor Ganas Ovarium Tipe Epitel
No

Nama

Usia

Paritas

1

SUP

52

P1A0

2

HER

46

P4A1

3

FAU

55

P3A0

4

MUR

42

P1A0

5

NUR

53

P7A3

6

ELF

35

P0A0

7

SUR

50

P1A0

8

IND

28

P0A0

9

NUR

51

P3A0

10

BER

40

P0A0

11

BON

66

P5A1

12
13

LEN
SOR

26
59

P1A0
P3A1

14

SUM

50

P5A0

Histopatology Jaringan

Cystadenocarcinoma Papillary
Mucinosum Ovarium
Cystadenocarcinoma Papillary
Mucinosum Ovarium
Cystadenocarcinoma Papillary
Serosum Ovarium
Cystadenocarcinoma Papillary
Serosum Ovarium
Cystadenocarcinoma Papillary
Serosum Ovarium
Cystadenocarcinoma Papillary
Serosum Ovarium
Cystadenocarcinoma Papillary
Mucinosum Ovarium
Cystadenocarcinoma Papillary
Mucinosum Ovarium
Cystadenocarcinoma Papillary
Serosum Ovarium
Cystadenocarcinoma Papillary
Mucinosum Ovarium

Cystadenocarcinoma Papillary
Mucinosum Ovarium
Adenocarcinoma Ovarium
Cystadenocarcinoma Papillary
Serosum Ovarium
Cystadenocarcinoma Papillary
Serosum Ovarium

Stadiu
m

intensitas

Observer 1
proporsi
Skor
Total

IIA

1

2

IC

0

IIIC

Observer 2
proporsi
Skor
Total

Skor
Allred

intensitas

Skor
Allred

3

Positif

2

1

3

Positif

0

0

Negatif

0

0

0

Negatif

0

0

0

Negatif

0

0

0

Negatif

IIIC

0

0

0

Negatif

0

0

0

Negatif

IIIC

1

3

4

Positif

1

3

4

Positif

IIIB

0

0

0

Negatif

0

0

0

Negatif

IIA

0

0

0

Negatif

0

0

0

Negatif

IIIC

3

3

3

Positif

3

3

6

Positif

IA

0

0

0

Negatif

0

0

0

Negatif

IIIC

0

0

0

Negatif

0

0

0

Negatif

IC

1

2

3

Positif

1

2

3

Positif

IIIC
IIIA

1
1

2
1

3
2

Positif
Negatif

1
1

1
1

2
2

Negatif
Negatif

IC

1

1

2

Negatif

1

1

2

Negatif

63

15

EMM

38

P0A0

16

ERP

33

P4A0

17
18

NET
LAS

47
47

P2A1
P0A0

19
20
21

MON
NEN
MAN

21
40
51

P1A0
POA1
P3A0

22
23

ROM
SUT

54
54

P4A2
P5A0

24

FIT

25

P0A0

25

SYF

44

P3A0

Cystadenocarcinoma Papillary
Serosum Ovarium
Cystadenocarcinoma Papillary
Mucinosum Ovarium
Adenocarcinoma Ovarium
Cystadenocarcinoma Papillary
Serosum Ovarium
Adenocarcinoma Ovarium
Adenocarcinoma Ovarium
Cystadenocarcinoma Papillary
Serosum Ovarium
Adenocarcinoma Ovarium
Cystadenocarcinoma Papillary
Serosum Ovarium
Cystadenocarcinoma Papillary
Mucinosum Ovarium
Cystadenocarcinoma Papillary
Mucinosum Ovarium

IIIC

0

0

0

Negatif

0

0

0

Negatif

IA

2

2

4

Positif

2

2

4

Positif

IA
IIIC

1
1

1
2

2
3

Negatif
Positif

1
1

1
2

2
3

Negatif
Positif

IVA
IC
IIIA

1
1
1

2
2
1

3
3
2

Positif
Positif
Negatif

1
1
1

2
1
1

3
2
2

Positif
Negatif
Negatif

IIIC
IIIC

1
0

1
0

2
0

Negatif
Negatif

1
0

1
0

2
0

Negatif
Negatif

IIIC

1

2

3

Positif

1

2

3

Positif

IA

0

0

0

Negatif

0

0

0

Negatif

64

Hasil Pemeriksaan KiSS1; Tumor Jinak Ovarium Tipe Epitel
No

1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25

Nama

UUN
LNA
UAH
NYR
YHI
FRD
TLM
IND
ROM
REO
HDG
DRS
SKL
IOT
EMA
KIA
TER
LIS
ELL
WDP
FKZ
PAL
NOR
VIT
ASH

Usia

56
43
51
40
53
36
44
28
52
45
69
27
58
51
38
34
44
48
21
39
34
54
54
25
44

Parita
s

Histopatology Jaringan

P2A0
P3A0
P1A0
P1A0
P7A1
P0A1
P1A1
P1A0
P1A0
P0A0
P3A1
P0A0
P0A0
P2A0
P0A0
P4A1
P2A1
P2A1
P1A0
POA1
P3A0
P4A2
P5A0
P0A0
P4A0

Adenoma Mucinosum Ovarii
Adenoma Serosum Ovarii
Adenoma Serosum Ovarii
Adenoma Serosum Ovarii
Adenoma Serosum Ovarii
Adenoma Serosum Ovarii
Adenoma Serosum Ovarii
Adenoma Mucinosum Ovarii
Adenoma Mucinosum Ovarii
Adenoma Serosum Ovarii
Adenoma Mucinosum Ovarii
Adenoma Mucinosum Ovarii
Adenoma Serosum Ovarii
Adenoma Mucinosum Ovarii
Adenoma Mucinosum Ovarii
Adenoma Mucinosum Ovarii
Adenoma Serosum Ovarii
Adenoma Serosum Ovarii
Adenoma Serosum Ovarii
Adenoma Serosum Ovarii
Adenoma Mucinosum Ovarii
Adenoma Mucinosum Ovarii
Adenoma Serosum Ovarii
Adenoma Serosum Ovarii
Adenoma Serosum Ovarii

intensit
as
0
0
0
0
0
1
1
1
1
1
0
0
0
0
1
0
0
0
0
1
0
1
0
1
0

Observer 1
proporsi
Skor
Total
0
0
0
0
0
0
0
0
0
0
1
2
1
2
2
3
1
2
1
2
0
0
0
0
0
0
0
0
1
2
0
0
0
0
0
0
0
0
1
2
0
0
1
2
0
0
1
2
0
0

Skor
Allred
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Positif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif

intensita
s
0
0
0
0
0
1
1
1
1
1
0
0
0
0
1
0
0
0
0
1
0
1
0
1
0

Observer 2
proporsi
Skor
Total
0
0
0
0
0
0
0
0
0
0
1
2
1
2
2
3
1
2
1
2
0
0
0
0
0
0
0
0
1
2
0
0
0
0
0
0
0
0
1
2
0
0
1
2
0
0
1
2
0
0

Skor
Allred
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Positif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif
Negatif

65

ANALISA STATISTIK

Explore
Descriptives
kel_diagnosa
skorallred

ganas

Statistic

Mean

1.6800

95% Confidence Interval for Lower Bound
Mean
Upper Bound

1.0640

5% Trimmed Mean

1.6444

Median

2.0000

.29844

2.2960

Variance

2.227

Std. Deviation

1.49220

Minimum

.00

Maximum

4.00

Range

4.00

Interquartile Range

3.00

Skewness

-.053

.464

-1.667

.902

Mean

.7600

.21040

95% Confidence Interval for Lower Bound
Mean
Upper Bound

.3258

Kurtosis
jinak

Std. Error

1.1942

5% Trimmed Mean

.6889

Median

.0000

Variance

1.107

Std. Deviation

1.05198

Minimum

.00

Maximum

3.00

Range

3.00

Interquartile Range

2.00

Skewness

.757

.464

-1.255

.902

Kurtosis
Tests of Normality
a

Kolmogorov-Smirnov
kel_diagno
sa
skorallred

Statistic

df

Shapiro-Wilk
Sig.

Statistic

df

Sig.

ganas

.270

25

.000

.805

25

.000

jinak

.405

25

.000

.661

25

.000

a. Lilliefors Significance Correction

66

NPar Tests
Mann-Whitney Test
Ranks
kel_diagnosa
skorallred

N

Mean Rank

Sum of Ranks

ganas

25

30.04

751.00

jinak

25

20.96

524.00

Total

50

a

Test Statistics

skorallred
Mann-Whitney U

199.000

Wilcoxon W

524.000

Z
Asymp. Sig. (2-tailed)

-2.408
.016

a. Grouping Variable: kel_diagnosa

67

Crosstabs
kel_skorallred * diagnosa Crosstabulation
Count
diagnosa

kel_skorallred

TUMOR OVARIUM

TUMOR OVARIUM

GANAS

JINAK

Total

Positif

10

1

11

negatif

15

24

39

25

25

50

Total

Chi-Square Tests

Value
Pearson Chi-Square
Continuity Correction

Exact Sig. (2-

Exact Sig. (1-

sided)

sided)

sided)

df
a

1

.002

7.459

1

.006

10.643

1

.001

9.441
b

Likelihood Ratio

Asymp. Sig. (2-

Fisher's Exact Test

.005

N of Valid Cases

.002

50

a. 0 cells (.0%) have expected count less than 5. The minimum expected count is 5.50.
b. Computed only for a 2x2 table

Risk Estimate
95% Confidence Interval
Value
Odds Ratio for kel_skorallred (Positif /

Lower

Upper

16.000

1.855

137.974

negatif)
For

cohort

diagnosa

=

TUMOR

2.364

1.524

3.666

=

TUMOR

.148

.022

.973

OVARIUM GANAS
For

cohort

diagnosa

OVARIUM JINAK
N of Valid Cases

50

68