Children with HIVAIDS Hospital Care WHO evidence 0

91 CHAPTER SUB-CHAPTER QUESTION 3.12 Other common neonatal problems For term, preterm and SGA neonates with hyperbilirubinemia P, when should the options of exchange transfusion be performed or phototherapy be instituted I, C, depending on day of life T, in preventing morbidity and sequalae O? 3.13 Babies of mothers with infections Among termnear term newborn infants born to mothers with risk factors for neonatal infection P, does the use of immediate prophylactic antibiotic I, compared to selective use of antibiotics C have an impact on neonatal mortality andor on neonatal sepsis O?

4. Cough or difficulty

breathing 4.2 Pneumonia In children aged 2–59 months P, what is the most effective antibiotic therapy I, C for very severe pneumonia O? In children aged 2–59 months P, what is the most effective antibiotic therapy I,C for severe pneumonia O? In children aged 2–59 months P, what is the most effective antibiotic regimen I, C for treatment of non- severe pneumonia O? For children aged 2–59 months P, should antibiotics be given I,C for non-severe pneumonia and wheeze O? 4.4 Conditions presenting with wheeze In children 2–59 months of age P, should oral salbutamol be used as a bronchodilator I,C to relieve acute wheeze and bronchoconstriction O? 5. Diarrhoea 5.4 Dysentery For children less than 5 years of age with bloody diarrhoea P, what is the effectiveness of the recommended antibiotic regimen I in preventing death or limiting complications O? 6. Fever 6.3 Meningitis In children aged 2–59 months in developing countries P, which parenteral antibiotic or combination of antibiotics I, at what dose and duration, is effective for the treatment of suspected bacterial meningitis in hospital in reducing mortality and sequelae O? 6.6 Typhoid fever In children with typhoid fever, P, what are the most effective antibiotics I, C, in preventing severe morbidity or preventing complications and death O? 6.7 Ear infections In children with acute otitis media, P, are antibiotics more effective than placebo I, C, in reducing duration of illness and clinical course O? In children aged 2–59 months P, what should be the first line antibiotic treatment I for chronic otitis media? In children aged 2–59 months P, what is the effectiveness of local topical antiseptics I in the treatment of chronic suppurative otitis media?