Antibiotics for severe pneumonia
13.11 Antibiotics for Meningitis
1. here is need for comparative studies on dose and frequency of cetriaxone, 2. Improved surveillance for antibiotic resistance among pathogens causing meningitis 3. he role and accuracy of rapid point of care diagnostic tests, that can be used in district hospitals that do not have culture facilities 4. Studies of the aetiology on meningoencephalitis in settings with high coverage of SPHib vaccine coverage13.12 Antibiotics for Acute Otitis Media
1. RCTs in developing countries with pragmatic deinition of otitis 2. Follow up studies in developing countries to quantify complication rates, especially in high prevalence HIV settings 3. Systematic review of treatment of otorrhoea as may merit separate guidelines 4. RCT of diferent durations of antibiotic treatment including BD versus TID13.13 Antibiotics for Typhoid Fever
1. Develop point of care diagnostic tests with higher speciicity than current tests 2. Deine local resistance patterns 3. Studies of basic epidemiology of typhoid in Africa 4. Continuing need for efective vaccine13.14 Antibiotics for severe acute malnutrition
1. he role of metronidazole in controlling intestinal bacterial overgrowth in children with Severe Acute Malnutrition? here is currently one ongoing trial in Senegal 2. he efectiveness of diferent antibiotic regimens in the treatment of complicated SAM. 3. A randomised controlled trial on the role of antibiotics in uncomplicated SAM.13.15 Oxygen systems and delivery methods
1. Large-scale efectiveness trials of improved oxygen systems on outcomes from pneumonia 2. Studies of alternative power supplies to run oxygen concentrators and pulse oximeters in remote settings where power supplies are unreliable 3. he role of inexpensive forms of CPAP in the management of severe pneumonia 4. Are there safe methods for cleaning and reuse of oxygen delivery equipment in high HIV prevalence settings?13.16 Pulse oximetry
1. Studies of diferent types of pulse oximetry – such as hand-held devices – in ield settingsParts
» Hospital Care WHO evidence 0
» Objectives of the recommendations
» Management of conflict of interest
» Defining the scope Methodology and process
» Evidence retrieval and synthesis process
» Consensus building and external peer review
» Review and update of the recommendations
» Proposed subsidiary products Implementation of the recommendations
» Implementation of the recommendations
» National adaptation and implementation
» Management of neonatal jaundice Empirical antibiotics for suspected neonatal sepsis
» Antibiotic treatment for non-severe pneumonia with no wheeze
» Inhaled salbutamol for treatment of acute wheezeasthma and
» Antibiotics for treatment of acute otitis media
» Clinical signs for detection of hypoxaemia in children
» Oxygen delivery methods Criteria for starting and stopping oxygen therapy
» Evidence and summary of findings
» Benefits and risks Acceptability and feasibility
» Evidence and summary of findings Benefits and risks
» Acceptability and feasibility Management of neonatal jaundice
» Benefits and risks Head or whole body cooling in management of hypoxic ischaemic
» Acceptability and feasibility Head or whole body cooling in management of hypoxic ischaemic
» Evidence and summary of recommendations
» Acceptability and feasibility Kangaroo Mother Care
» Benefits and risks Prevention of hypothermia immediately after birth in low birth
» Acceptability and feasibility Prevention of hypothermia immediately after birth in low birth
» Benefits and risks Antibiotic treatment for non-severe pneumonia with wheeze
» Acceptability and feasibility Antibiotic treatment for non-severe pneumonia with wheeze
» Benefits and risks Antibiotic treatment for non-severe pneumonia with no wheeze
» Acceptability and feasibility Antibiotic treatment for non-severe pneumonia with no wheeze
» Benefits and risks Antibiotics treatment for severe pneumonia
» Acceptability and feasibility Antibiotics treatment for severe pneumonia
» Evidence and summary of findings Benefits and risks Acceptability and feasibility
» Acceptability and feasibility Salbutamol for treatment of acute wheezeasthma and
» Acceptability and feasibility Antibiotics for treatment of acute bacterial meningitis
» Benefits and risks Antibiotic treatment for Acute Otitis Media AOM
» Acceptability and feasibility Antibiotic treatment for Chronic Suppurative Otitis Media CSOM
» Benefits and risks Topical steroids for treatment of Chronic Suppurative Otitis Media
» Acceptability and feasibility Topical steroids for treatment of Chronic Suppurative Otitis Media
» Benefits and risks Antibiotic treatment for Typhoid Fever
» Acceptability and feasibility: Antibiotic treatment for Typhoid Fever
» Benefits and risks Antibiotics use in the management of severe acute malnutrition
» Acceptability and feasibility Antibiotics use in the management of severe acute malnutrition
» Acceptability and feasibility: Oxygen therapy in treatment of hypoxaemia
» Acceptability and feasibility Oxygen therapy delivery methods
» Benefits and risks Criteria for starting and stopping oxygen therapy
» Acceptability and feasibility Criteria for starting and stopping oxygen therapy
» Benefits and risks Sublingual administration of sugar in treatment of hypoglycaemia
» Acceptability and feasibility Sublingual administration of sugar in treatment of hypoglycaemia
» Benefits and risks Choice of intravenous fluids for resuscitation and maintenance in
» Vitamin K prophylaxis in newborns
» Skin-to-skin contact in the first hour of life
» Management of neonatal jaundice
» Kangaroo Mother Care Outline of the research gaps
» Prevention of hypothermia immediately after birth in VLBW infants
» Management of children with non-severe pneumonia and wheeze
» Antibiotics for severe pneumonia
» Antibiotics for very severe pneumonia
» Treatment of non-severe pneumonia
» Problems of the neonate and young infant
» Fever Severe malnutrition Hospital Care WHO evidence 0
» Children with HIVAIDS Hospital Care WHO evidence 0
» Common surgical conditions Hospital Care WHO evidence 0
» Supportive care Hospital Care WHO evidence 0
» Monitoring the child’s progress
» Counselling and discharge from hospital
Show more