Problems of the neonate and young infant

89 CHAPTERSECTION NO CHANGE REQUIRED ALIGN WITH RECENT WHO GUIDELINES NEW RECOMMENDATIONS 7.3 Organization of care ✔ 7.4 General treatment ✔ 7.5 Treatment of associated conditions ✔ 7.6 Discharge and follow-up ✔ 7.7 Monitoring the quality of care ✔

8. Children with HIVAIDS

All sub-chapters ✔

9. Common surgical conditions

All sub-chapters ✔

10. Supportive care

10.1 Nutritional management ✔ 10.2 Fluid management ✔ 10.3 Management of fever ✔ 10.4 Pain control ✔ 10.5 Management of anaemia ✔ 10.6 Blood transfusion ✔ 10.7 Oxygen therapy ✔ 10.8 Toys and play therapy ✔

11. Monitoring the child’s progress

All sub-chapters ✔

12. Counselling and discharge from hospital

All sub-chapters ✔ Appendices 1. Practical procedures ✔ 2. Drug dosagesregimens ✔ 3. Equipment size for children ✔ 4. Intravenous fluids ✔ 5. Assessing nutritional status ✔ 6. Job aids and charts ✔ Represents sections where no or editorial changes are expected to be made in the pocket book. Represents sections where changes will be made to align with new recommendations guidelines already approved through GRC Represents sections where evidence was reviewed and recommendations made by the expert panel meeting in February 2011 are provided in this publication. 90 ANNEX 2 List of PICO questions CHAPTER SUB-CHAPTER QUESTION

3. Problems of the neonate

and young infant 3.1 Routine care of the newborn at delivery Among healthy newborn infants in low- and middle- income countries P, does early skin-to-skin contact of the baby with the mother in the first hour of life I compared with drying and wrapping C have an impact on neonatal mortality, hypothermia or initiation exclusivity duration of breastfeeding O? 3.3 Routine care for all newborn babies after delivery For all neonates P, should vitamin K prophylaxis I be given for the prevention of vitamin K deficiency bleeding O? 3.5 Management of the child with perinatal asphyxia For neonates requiring prolonged resuscitation and at risk of HIE P, should head or body cooling I be initiated to prevent death and sequelae O? 3.7 Serious bacterial infections For young infants 0-2 months with suspected sepsis managed in health facilities P, should third generation cephalosporin monotherapy I replace currently recommended ampicillin-gentamicin combination C as first line empiric treatment for preventing death and sequelae O? 3.10 Babies with low birth weight In low-birth-weightpre-term neonates in health facilities P, are plastic wraps or caps used immediately after birth I more effective than conventional care C in preventing hypothermia O? In low-birth-weightpre-term neonates in health facilities P, is skin to skin contact immediately after birth I more effective than conventional care C in preventing hypothermia O? In low-birth-weightpre-term neonates in health facilities P, is Kangaroo Mother Care I more effective than conventional care C in reducing mortality andor morbidity O? 3.11 Necrotising enterocolitis For young infants with suspected NEC P, what is the effectiveness of different parenteral antibiotics I, C in preventing progression and sequelae O?