Hubungan Antara Profil Lipid Dengan Rasio Proinsulin Insulin Pada Individu Dengan Toleransi Glukosa Normal
36
DAFTAR PUSTAKA
1. Zheng T, Gao Y, Tian H. Relationship between blood lipid profiles and
pancreatic islet β cell function in Chinese men and women with normal
glucose tolerance: across-sectional study. BMC Public Health. 2012,
12:634.
2. Kawamoto R, Tabara Y, Kohara K, Miki T, Kusunoki T, Takayama S, et
all. Relationships between lipid profiles and metabolic syndrome, insulin
resistance and serum high molecular adiponectin in Japanese communitydwelling adults. Lipids in Health and Disease. 2011, 10:79.
3. Du.T, Yuan.G, Zhang.M, Zhou.X, Sun.X, Yu. X. Clinical usefulness of
lipid ratios, visceral adiposity indicators, and the triglycerides and glucose
index as risk markers of insulin resistance. Cardiovascular Diabetology
.2014, 13:146.
4. Perkumpulan Endokrinologi Indonesia. Konsensus Pengelolaan dan
Pencegahan Diabetes Melitus Tipe 2 di Indonesia 2015, PB. PERKENI.
Jakarta 2015.
5. Purnamasari D. Buku Ajar Ilmu Penyakit Dalam: Diagnosis dan Klasifikasi
Diabetes Melitus. Edisi V. Jakarta Pusat: Interna Publishing; 2011; 292:
1880-1883.
6. Bardini. G, Rotella. C. M, Giannini. S. Dyslipidemia and Diabetes:
Reciprocal Impact of Impaired Lipid Metabolism and Beta-Cell
Dysfunction on Micro- and Macrovascular Complications. The Review Of
Diabetic Studies. 2012.
7. Usgaonkar A.P, Dhume.C. Y, Amonkar. S.D. Comparative assessment of
insulin sensitivity and pancreatic beta cell function in diabetics and nondiabetics. International Journal of Pharma and Bio Sciences. Vol: 3 Issue 1,
Jan – Mar 2012.
8. Roehrich. M. E , Mooser. R ,Lenain. V, Herz. J, Nimpf. J, Azhar.S.et all
Insulin-secreting -Cell Dysfunction Induced by Human Lipoproteins. The
Journal Of Biological Chemistry Vol. 278, No. 20, Issue of May 16, pp.
18368–18375, 2003
Universitas Sumatera Utara
37
9. Pradhan.A.D, Manson.E.J, Meigs.B.J, Rifai.N, Buring.E.J, Liu.S, et all.
Insulin, Proinsulin, Proinsulin:Insulin Ratio, and the Risk of Developing
Type 2 Diabetes Mellitus in Women. Am J Med. 2003;114:438–444
10. Ma.Yuang, Wang.Y, Huang.Q, Ren.Q, Chen.S, Zhang. A,et all Impaired �
Cell Function in Chinese Newly Diagnosed Type 2 Diabetes Mellitus with
Hyperlipidemia. Diabetes Research.2014
11. Eckardstein.V.A, Sibler.R.A. Possible Contributions Of Lipoproteins And
Cholesterol To The Pathogenesis Of Diabetes Mellitus Type 2. Current
Opinion in Lipidology 2011, 22:26–32
12. Bhattacharya. S, Dey. D, Sankar. R.S .Molecular mechanism of insulin
resistance. Indian Academy of Sciences. J. Biosci. 32(2). 405–413: 2007.
13. Pfutzner A, Derwahl M, Jacob S, Hohberg C, Blummer ELehmann U, et al:
Limitations of the HOMA-B Score for Assessment of b-Cell Functionality
in Interventional Trials-Results from PIOglim study. Diabetes Technology
& Therapeutic,(12).599-604.(2010)
14. Poitout .Vincent, Secondary Cell Failure in Type 2 Diabetes A Convergence
of Glucotoxicity and Lipotoxicitas. Endocrinology 143(2):339–342.(2002)
15. Pfutzner.A, Karin. P.H, Pfutzner.A. H, Kunt.T, Larbig. M, Weber M.M.et
all. Intact and total proinsulin : new aspect for diagnosis and treatment of
type 2 diabetes mellitus and insulin resistance. Clin Lab. 2004;50(910):666-92
16. Pfützner.A, Kunt. T, Langenfeld. M, Löbig. M, Knesovic. M, Forst T.
Clinical and laboratory evaluation of specific chemiluminescence assays for
intact and total proinsulin. Clin Chem Lab Med. 2003;41(9):1234–8.
17. Fritsche. A, Madaus. A, Stefan. N, Tschritter. O, Maerker. E, Teigeler. A,et
all. Relationships Among Age, Proinsulin Conversion, and Cell Function in
Nondiabetic Humans. Diabetes 51 (Suppl. 1):S234–S239, 2002
18. Haffner SM, Mykkanen L, Valdez RA, Stern MP, Holloway DL,
Monterrosa A, Bowsher RR. Disproportionately increased proinsulin levels
are associated with insulin resistance syndrome. J Clin Endocrinol Metab.
1994; 79(6):1806-10
Universitas Sumatera Utara
38
19. Karam JH, Forsham PH: Endokrinologi dasar & klinik: hormon-hormon
pankreas & Diabetes melitus. EGC 2000; 15: 745-748.
20. Pfützner A, Standl E, Hohberg C, Konrad T, Strotmann HJ, Lübben G,
Langenfeld MR, Schulze J, Forst T. IRIS II study: intak proinsulin is
confirmed as a highly specific indicator for insulin resistance in a large
cross-sectional study design. Diabetes Technol Ther. 2005;7(3):478–86.
21. Saisho Y, Maruyama T, Hirose H, Saruta T: Relationship between
proinsulin-to-insulin ratio and advanced glycation endproducts in Japanese
type 2 diabetic subjects. Diabetes Research and Clinical Practice, 2007; 78;
182-188.
22. Soegondo S. 2014. Obesitas Dalam: Buku Ajar Ilmu Penyakit Dalam. Jilid
3. Edisi VI. Jakarta:Departemen Ilmu Penyakit Dalam Fakultas Kedokteran
Universitas Indonesia. Hal;2559- 2569
23. World Health Organization, global data of Body Mass Index Source:
Adapted from WHO, 1995, WHO, 2000 and WHO 2004.
24. Unger RH, Orci L. Paracrinology of islets and the paracrinopathy of
diabetes. Proc Natl Acad Sci U S A. 2010 Sep 14. 107(37):16009
25. Kawamoto R, Tabara Y, Kohara K, Miki T, Kusunoki T, Takayama S, et
all. Relationships between lipid profiles and metabolic syndrome, insulin
resistance and serum high molecular adiponectin in Japanese communitydwelling adults. Lipids in Health and Disease 10:79, 2011
26. Grill.V,
Dinesen.B,
Carlsson.S,
Efendic.S,
Pedersen.O,Östenson.G:
Hyperproinsulinemia and Proinsulin-to-Insulin Ratios in Swedish Middleaged Men: Association with Glycemia and Insulin Resistance but Not with
Family History of Diabetes; American Journal of Epidemiology 155: 9,
2002
27. Mykkanen. L, Haffher. S.M , Hales.C.N, Ronnemaa.T, Laakso.M. The
Relation of Proinsulin, Insulin, and Proinsulin-to-Insulin Ratio to Insulin
Sensitivity and Acute Insulin Response in Normoglycemic Subjects.
Diabetes, vol. 46,1997.
Universitas Sumatera Utara
39
28. Festa.A,
D’agostino.Jr.
R.,
Mykkänen.
L,
Tracy.R.P,
Hales.C.N,
Howard.V.B , et all. LDL Particle Size in Relation to Insulin, Proinsulin,
and Insulin Sensitivity. Diabetes Care 22:1688–1693, 1999
29. Du.Tingting,Yuan.Gang, Zhang.Muxun, Zhou.Xinrong, Sun. Xingxing,
Yu.Xuefung. Clinical usefulness of lipid ratios, visceral adiposity indicators,
and the triglycerides and glucose index as risk markers of insulin resistance.
Cardiovascular Diabetology 13:146,2014
30. I.Shiraishi,Y.Iwamoto,T.Kuzuya,A.M.Kumakura.Hyperinsulinaemia
in
obesity is not accompanied by an increase in serum proinsulin/insulin ratio
in groups of human subjects with and without glucose intolerance.
Diabetologia (1991) 34:737-7
31. Hanley J.G.A, Mckeown-Eyssen.G, Harris S.B Hegele.R.A, Wolever
M.S.T, Jeremy Kwan J,et all Cross-Sectional and Prospective Associations
betweAbdominal Adiposity and Proinsulin Concentration. J Clin Endocrinol
Metab 87: 77–83, 2002
32. Sasaki.R, Yano.Y,Yasuma.T,Onishi.Y,Suzuki.T, Maruyama-Furuta.N.et all
Association of Waist Circumference and Body Fat Weight with Insulin
Resistance in Male Subjects with Normal Bod Mass Index and Normal
Glucose Tolerance. Intern Med 55: 1425-1432, 2016
33. Chan D dkk. Adiponectin and other Adipocytokines as Predictors of
markers of triglyceride-Rich Lipoporotein Metabolism. Clinical Chemistry
2005;51(3):578-585.
34. Furukawa. H,
Carroll.R.J, Swift.H.H,
Steiner.D.F. L o n g - Term
Elevation of Free Fatty Acids Leads to Delayed Processing of Proinsulin
and Prohormone Convertases 2 and 3 in the Pancreatic b-Cell Line MIN6.
Diabetes, vol. 48.1999
Universitas Sumatera Utara
DAFTAR PUSTAKA
1. Zheng T, Gao Y, Tian H. Relationship between blood lipid profiles and
pancreatic islet β cell function in Chinese men and women with normal
glucose tolerance: across-sectional study. BMC Public Health. 2012,
12:634.
2. Kawamoto R, Tabara Y, Kohara K, Miki T, Kusunoki T, Takayama S, et
all. Relationships between lipid profiles and metabolic syndrome, insulin
resistance and serum high molecular adiponectin in Japanese communitydwelling adults. Lipids in Health and Disease. 2011, 10:79.
3. Du.T, Yuan.G, Zhang.M, Zhou.X, Sun.X, Yu. X. Clinical usefulness of
lipid ratios, visceral adiposity indicators, and the triglycerides and glucose
index as risk markers of insulin resistance. Cardiovascular Diabetology
.2014, 13:146.
4. Perkumpulan Endokrinologi Indonesia. Konsensus Pengelolaan dan
Pencegahan Diabetes Melitus Tipe 2 di Indonesia 2015, PB. PERKENI.
Jakarta 2015.
5. Purnamasari D. Buku Ajar Ilmu Penyakit Dalam: Diagnosis dan Klasifikasi
Diabetes Melitus. Edisi V. Jakarta Pusat: Interna Publishing; 2011; 292:
1880-1883.
6. Bardini. G, Rotella. C. M, Giannini. S. Dyslipidemia and Diabetes:
Reciprocal Impact of Impaired Lipid Metabolism and Beta-Cell
Dysfunction on Micro- and Macrovascular Complications. The Review Of
Diabetic Studies. 2012.
7. Usgaonkar A.P, Dhume.C. Y, Amonkar. S.D. Comparative assessment of
insulin sensitivity and pancreatic beta cell function in diabetics and nondiabetics. International Journal of Pharma and Bio Sciences. Vol: 3 Issue 1,
Jan – Mar 2012.
8. Roehrich. M. E , Mooser. R ,Lenain. V, Herz. J, Nimpf. J, Azhar.S.et all
Insulin-secreting -Cell Dysfunction Induced by Human Lipoproteins. The
Journal Of Biological Chemistry Vol. 278, No. 20, Issue of May 16, pp.
18368–18375, 2003
Universitas Sumatera Utara
37
9. Pradhan.A.D, Manson.E.J, Meigs.B.J, Rifai.N, Buring.E.J, Liu.S, et all.
Insulin, Proinsulin, Proinsulin:Insulin Ratio, and the Risk of Developing
Type 2 Diabetes Mellitus in Women. Am J Med. 2003;114:438–444
10. Ma.Yuang, Wang.Y, Huang.Q, Ren.Q, Chen.S, Zhang. A,et all Impaired �
Cell Function in Chinese Newly Diagnosed Type 2 Diabetes Mellitus with
Hyperlipidemia. Diabetes Research.2014
11. Eckardstein.V.A, Sibler.R.A. Possible Contributions Of Lipoproteins And
Cholesterol To The Pathogenesis Of Diabetes Mellitus Type 2. Current
Opinion in Lipidology 2011, 22:26–32
12. Bhattacharya. S, Dey. D, Sankar. R.S .Molecular mechanism of insulin
resistance. Indian Academy of Sciences. J. Biosci. 32(2). 405–413: 2007.
13. Pfutzner A, Derwahl M, Jacob S, Hohberg C, Blummer ELehmann U, et al:
Limitations of the HOMA-B Score for Assessment of b-Cell Functionality
in Interventional Trials-Results from PIOglim study. Diabetes Technology
& Therapeutic,(12).599-604.(2010)
14. Poitout .Vincent, Secondary Cell Failure in Type 2 Diabetes A Convergence
of Glucotoxicity and Lipotoxicitas. Endocrinology 143(2):339–342.(2002)
15. Pfutzner.A, Karin. P.H, Pfutzner.A. H, Kunt.T, Larbig. M, Weber M.M.et
all. Intact and total proinsulin : new aspect for diagnosis and treatment of
type 2 diabetes mellitus and insulin resistance. Clin Lab. 2004;50(910):666-92
16. Pfützner.A, Kunt. T, Langenfeld. M, Löbig. M, Knesovic. M, Forst T.
Clinical and laboratory evaluation of specific chemiluminescence assays for
intact and total proinsulin. Clin Chem Lab Med. 2003;41(9):1234–8.
17. Fritsche. A, Madaus. A, Stefan. N, Tschritter. O, Maerker. E, Teigeler. A,et
all. Relationships Among Age, Proinsulin Conversion, and Cell Function in
Nondiabetic Humans. Diabetes 51 (Suppl. 1):S234–S239, 2002
18. Haffner SM, Mykkanen L, Valdez RA, Stern MP, Holloway DL,
Monterrosa A, Bowsher RR. Disproportionately increased proinsulin levels
are associated with insulin resistance syndrome. J Clin Endocrinol Metab.
1994; 79(6):1806-10
Universitas Sumatera Utara
38
19. Karam JH, Forsham PH: Endokrinologi dasar & klinik: hormon-hormon
pankreas & Diabetes melitus. EGC 2000; 15: 745-748.
20. Pfützner A, Standl E, Hohberg C, Konrad T, Strotmann HJ, Lübben G,
Langenfeld MR, Schulze J, Forst T. IRIS II study: intak proinsulin is
confirmed as a highly specific indicator for insulin resistance in a large
cross-sectional study design. Diabetes Technol Ther. 2005;7(3):478–86.
21. Saisho Y, Maruyama T, Hirose H, Saruta T: Relationship between
proinsulin-to-insulin ratio and advanced glycation endproducts in Japanese
type 2 diabetic subjects. Diabetes Research and Clinical Practice, 2007; 78;
182-188.
22. Soegondo S. 2014. Obesitas Dalam: Buku Ajar Ilmu Penyakit Dalam. Jilid
3. Edisi VI. Jakarta:Departemen Ilmu Penyakit Dalam Fakultas Kedokteran
Universitas Indonesia. Hal;2559- 2569
23. World Health Organization, global data of Body Mass Index Source:
Adapted from WHO, 1995, WHO, 2000 and WHO 2004.
24. Unger RH, Orci L. Paracrinology of islets and the paracrinopathy of
diabetes. Proc Natl Acad Sci U S A. 2010 Sep 14. 107(37):16009
25. Kawamoto R, Tabara Y, Kohara K, Miki T, Kusunoki T, Takayama S, et
all. Relationships between lipid profiles and metabolic syndrome, insulin
resistance and serum high molecular adiponectin in Japanese communitydwelling adults. Lipids in Health and Disease 10:79, 2011
26. Grill.V,
Dinesen.B,
Carlsson.S,
Efendic.S,
Pedersen.O,Östenson.G:
Hyperproinsulinemia and Proinsulin-to-Insulin Ratios in Swedish Middleaged Men: Association with Glycemia and Insulin Resistance but Not with
Family History of Diabetes; American Journal of Epidemiology 155: 9,
2002
27. Mykkanen. L, Haffher. S.M , Hales.C.N, Ronnemaa.T, Laakso.M. The
Relation of Proinsulin, Insulin, and Proinsulin-to-Insulin Ratio to Insulin
Sensitivity and Acute Insulin Response in Normoglycemic Subjects.
Diabetes, vol. 46,1997.
Universitas Sumatera Utara
39
28. Festa.A,
D’agostino.Jr.
R.,
Mykkänen.
L,
Tracy.R.P,
Hales.C.N,
Howard.V.B , et all. LDL Particle Size in Relation to Insulin, Proinsulin,
and Insulin Sensitivity. Diabetes Care 22:1688–1693, 1999
29. Du.Tingting,Yuan.Gang, Zhang.Muxun, Zhou.Xinrong, Sun. Xingxing,
Yu.Xuefung. Clinical usefulness of lipid ratios, visceral adiposity indicators,
and the triglycerides and glucose index as risk markers of insulin resistance.
Cardiovascular Diabetology 13:146,2014
30. I.Shiraishi,Y.Iwamoto,T.Kuzuya,A.M.Kumakura.Hyperinsulinaemia
in
obesity is not accompanied by an increase in serum proinsulin/insulin ratio
in groups of human subjects with and without glucose intolerance.
Diabetologia (1991) 34:737-7
31. Hanley J.G.A, Mckeown-Eyssen.G, Harris S.B Hegele.R.A, Wolever
M.S.T, Jeremy Kwan J,et all Cross-Sectional and Prospective Associations
betweAbdominal Adiposity and Proinsulin Concentration. J Clin Endocrinol
Metab 87: 77–83, 2002
32. Sasaki.R, Yano.Y,Yasuma.T,Onishi.Y,Suzuki.T, Maruyama-Furuta.N.et all
Association of Waist Circumference and Body Fat Weight with Insulin
Resistance in Male Subjects with Normal Bod Mass Index and Normal
Glucose Tolerance. Intern Med 55: 1425-1432, 2016
33. Chan D dkk. Adiponectin and other Adipocytokines as Predictors of
markers of triglyceride-Rich Lipoporotein Metabolism. Clinical Chemistry
2005;51(3):578-585.
34. Furukawa. H,
Carroll.R.J, Swift.H.H,
Steiner.D.F. L o n g - Term
Elevation of Free Fatty Acids Leads to Delayed Processing of Proinsulin
and Prohormone Convertases 2 and 3 in the Pancreatic b-Cell Line MIN6.
Diabetes, vol. 48.1999
Universitas Sumatera Utara