2. KMK FK USU 2011-sekarang - Skrining Enterobactericeae Penghasil Extended Spectrum Beta-Lactamase dengan Metode Uji Double Disk Synergy Pada Sampel Urin Pasien Suspek Infeksi Saluran Kemih di RSUP. H. Adam Malik Medan

  Lampiran 1

Data Pribadi

  Nama Lengkap Jenis Kelamin Tempat Tanggal Lahir Warga Negara Status Agama Alamat Mobile E-mail

  

: NATALIA RASTA MALEM

: Perempuan : Jakarta, 26 Desember 1992 : Indonesia : Belum Menikah : Kristen Protestan : Jl. Dr. Sumarsono No. 8 Medan, 20154 : 0817110823 : barus.natalia@ymail.com Latar Belakang Pendidikan

  1999- 2005 2005 - 2008 2008 - 2011 2011 - Sekarang

  : SD Santo Markus II Jakarta : SMP N 115 Jakarta : SMA N 8 Jakarta

: Fakultas Kedokteran Universitas Sumatera Utara

Pengalaman Organisasi :

  1. PEMA FK USU 2012-2013

  2. KMK FK USU 2011-sekarang

Pengalaman Kepanitiaan :

  1. Panitia Natal FK USU 2011-2013

  2. Panitia Manajemen Mahasiswa Baru 2012

  3. Panitia Paskah FK USU 2012-2013

  4. Panitia Porseni FK USU 2013

  5. Panitia Bakti Sosial Mahasiswa Kristen Fakultas Kedokteran USU 2013-2014 Pengalaman Seminar dan Pelatihan:

  1. Seminar dan Workshop Basic Life Support dan Traumatology TBM FK USU 2012

  Lampiran 2 Hasil Skrining Enterobacteriaceae Penghasil ESBL dengan Metode Uji Double Disk Synergy No Nama Bakteri Hasil SkriningESBL Umur Jenis Kelamin

  58 L

  45 P

  19 K. Pneumoniae +

  74 L

  20 E. Coli -

  14 L

  21 E. Coli +

  51 P

  22 Enterobacter sp. +

  40 P

  23 K. Pneumoniae -

  72 L

  24 E. Coli -

  51 P

  25 E. Coli -

  26 E. Coli +

  60 L

  50 L

  27 E. Coli -

  14 L

  28 E. Coli +

  41 L

  29 K. Pneumoniae +

  61 L

  30 Enterobacter sp. -

  66 L

  31 Enterobacter sp. -

  54 L

  32 K. Pneumoniae +

  46 P

  33 E. Coli +

  18 Enterobacter sp. +

  17 E. Coli -

  1 E. Coli -

  22 L

  42 P

  2 K. Pneumoniae -

  44 L

  3 E. Coli -

  17 L

  4 E. Coli -

  14 L

  5 E. Coli -

  44 L

  6 E. Coli -

  69 L

  7 K. Pneumoniae -

  88 L

  8 E. Coli -

  9 K. Pneumoniae -

  45 L

  45 P

  10 E. Coli +

  55 L

  11 E. Coli -

  56 P

  12 E. Coli -

  46 L

  13 E. Coli +

  78 L

  14 E. Coli +

  47 L

  15 K. Pneumoniae -

  44 L

  16 Enterobacter sp. -

  79 L

  34 E. Coli -

  54 L

  45 E. Coli -

  14 L

  44 E. Coli -

  64 L

  43 K. Pneumoniae +

  36 L

  42 E. Coli -

  53 P

  41 E. Coli -

  40 K. Pneumoniae -

  51 L

  72 L

  39 E. Coli -

  48 L

  38 K. Pneumoniae +

  63 L

  37 E. Coli -

  47 L

  36 K. Pneumoniae +

  51 L

  35 E. Coli -

  49 P

  Tabel Pola Kepekaan Enterobacteriaceae Penghasil ESBL terhadap Antibiotika Keterangan: TZP : Tazobactam PRL : Piperacilllin TE : Tetracyclin MEM : Meropenem OFL: Ofloxacin CXM : Cefuroxime AMP : Ampicillin CAZ : Ceftazidime CTX : Cefotaxime

  9 E. coli S R R

  I R R S R R R R S R R R S R R R R

  15 K. pneumoniae

  I R R S R R R R

  I S R

  14 K. pneumoniae S R R S R R

  

13 K. pneumoniae R R R R R R R R S R R R S R R R R

  I R S R R R R R S R R R R

  12 E. coli S R R S

  I S

  I S S R R S S R S

  11 K. pneumoniae S R R S R R

  I R R S R R R R R R R R S R R R R

  10 K. pneumoniae

  I R R R R R R R R S R R R R

  

8 E. coli S R R S R R S S S S R R S R R R R

  FEP : Cefepim K : Kanamicin CRO : Ceftriaxone CIP : Ciprofloxacin AK : Amikacin C : Chloramphenicol

  4 Enterobacter sp S R R S R R

  

No Nama Bakteri TZP CXM FEP AK PRL AMP K C TE CAZ CRO SXT MEM CTX CIP NOR OFL

  1 E. coli S R R S R R R S R R R R S R R R R

  2 E. coli S R R S R R R S S R R

  I R R R R R

  3 E. coli S R

  I S R R S S S R R R S R R S S

  I I S R R R R R S S S

  I R S R S R R R R R R R R R R R

  5 K. pneumoniae S R R S

  I I

  I R S R R S S R R R R

  6 Enterobacter sp R R R

  I R R R R R R R R S R R R R

  7 E. coli S

SXT : Cotrimoxazole NOR : Norfloxacin

  Lampiran 3 Data SPSS Crosstabulation Uji Kepekaan Enterobacteriaceae Penghasil ESBL Terhadap Tazobactam

  Enterobacter sp Count

  Cefuroxime Total

  I R spesies bakteri E. coli

  Count

  1

  6

  7 % within spesies bakteri 14.3% 85.7% 100.0%

  2

  15 % within spesies bakteri 13.3% 13.3% 73.3% 100.0%

  2 % within spesies bakteri 0.0% 100.0% 100.0%

  K. pneumoniae Count

  6

  6 % within spesies bakteri 0.0% 100.0% 100.0%

  Total Count

  1

  14

  Crosstabulation Uji Kepekaan Enterobacteriaceae Penghasil ESBL Terhadap Cefuroxime

  11

  Tazobactam Total

  1

  I R S spesies bakteri E. coli

  Count

  7

  7 % within spesies bakteri 0.0% 0.0% 100.0% 100.0%

  Enterobacter sp Count

  1

  2 % within spesies bakteri 0.0% 50.0% 50.0% 100.0%

  2

  K. pneumoniae Count

  2

  1

  3

  6 % within spesies bakteri 33.3% 16.7% 50.0% 100.0%

  Total Count

  2

  15 % within spesies bakteri 6.7% 93.3% 100.0%

  Crosstabulation Uji Kepekaan Enterobacteriaceae Penghasil ESBL Terhadap Amikacin Crosstabulation Uji Kepekaan Enterobacteriaceae Penghasil ESBL Terhadap Piperacillin

  2 % within spesies bakteri 50.0% 0.0% 50.0% 100.0%

  1

  6

  7 % within spesies bakteri 14.3% 0.0% 85.7% 100.0%

  Enterobacter sp Count

  1

  1

  K. pneumoniae Count

  I R S spesies bakteri E. coli

  1

  5

  6 % within spesies bakteri 0.0% 16.7% 83.3% 100.0%

  Total Count

  2

  1

  12

  Count

  Amikacin Total

  Piperacillin Total

  2

  I R spesies bakteri E. coli

  Count

  1

  6

  7 % within spesies bakteri 14.3% 85.7% 100.0%

  Enterobacter sp Count

  2 % within spesies bakteri 0.0% 100.0% 100.0%

  15 % within spesies bakteri 13.3% 86.7% 100.0%

  K. pneumoniae Count

  1

  5

  6 % within spesies bakteri 16.7% 83.3% 100.0%

  Total Count

  2

  13

  15 % within spesies bakteri 13.3% 6.7% 80.0% 100.0%

  Crosstabulation Uji Kepekaan Enterobacteriaceae Penghasil ESBL Terhadap Ampicillin

  2 % within spesies bakteri 50.0% 50.0% 0.0% 100.0%

  Count

  4

  3

  7 % within spesies bakteri 0.0% 57.1% 42.9% 100.0%

  Enterobacter sp Count

  1

  1

  K. pneumoniae Count

  Kanamicin Total

  3

  3

  6 % within spesies bakteri 50.0% 50.0% 0.0% 100.0%

  Total Count

  4

  8

  3

  I R S spesies bakteri E. coli

  Crosstabulation Uji Kepekaan Enterobacteriaceae Penghasil ESBL Terhadap Kanamicin

  Ampicillin Total

  2 % within spesies bakteri 0.0% 100.0% 0.0% 100.0%

  I R S spesies bakteri E. coli

  Count

  6

  1

  7 % within spesies bakteri 0.0% 85.7% 14.3% 100.0%

  Enterobacter sp Count

  2

  K. pneumoniae Count

  15 % within spesies bakteri 6.7% 86.7% 6.7% 100.0%

  1

  5

  6 % within spesies bakteri 16.7% 83.3% 0.0% 100.0%

  Total Count

  1

  13

  1

  15 % within spesies bakteri 26.7% 53.3% 20.0% 100.0%

  Crosstabulation Uji Kepekaan Enterobacteriaceae Penghasil ESBL Terhadap Tetracyclin Crosstabulation Uji Kepekaan Enterobacteriaceae Penghasil ESBL Terhadap Chloramphenicol

  1

  E. coli Count

  4

  3

  7 % within spesies bakteri 57.1% 42.9% 100.0%

  Enterobacter sp Count

  1

  2 % within spesies bakteri 50.0% 50.0% 100.0%

  15 % within spesies bakteri 6.7% 53.3% 40.0% 100.0%

  K. pneumoniae Count

  2

  4

  6 % within spesies bakteri 33.3% 66.7% 100.0%

  Total Count

  7

  8

  Tetracyclin Total R S spesies bakteri

  6

  Chlorampenicol Total

  1

  I R S spesies bakteri E. coli

  Count

  3

  4

  7 % within spesies bakteri 0.0% 42.9% 57.1% 100.0%

  Enterobacter sp Count

  1

  8

  2 % within spesies bakteri 50.0% 50.0% 0.0% 100.0%

  K. pneumoniae Count

  4

  2

  6 % within spesies bakteri 0.0% 66.7% 33.3% 100.0%

  Total Count

  1

  15 % within spesies bakteri 46.7% 53.3% 100.0%

  Crosstabulation Uji Kepekaan Enterobacteriaceae Penghasil ESBL Terhadap Ceftriaxone

  Count

  1

  13

  1

  Total Count

  6 % within spesies bakteri 16.7% 83.3% 0.0% 100.0%

  5

  1

  K. pneumoniae Count

  2 % within spesies bakteri 0.0% 100.0% 0.0% 100.0%

  2

  Enterobacter sp Count

  7 % within spesies bakteri 0.0% 85.7% 14.3% 100.0%

  1

  6

  I R S spesies bakteri E. coli

  Ceftriaxone Total R spesies bakteri

  Ceftazidime Total

  Crosstabulation Uji Kepekaan Enterobacteriaceae Penghasil ESBL Terhadap Ceftazidime

  15 % within spesies bakteri 100.0% 100.0%

  15

  Total Count

  6 % within spesies bakteri 100.0% 100.0%

  6

  K. pneumoniae Count

  2 % within spesies bakteri 100.0% 100.0%

  2

  Enterobacter sp Count

  7 % within spesies bakteri 100.0% 100.0%

  7

  E. coli Count

  15 % within spesies bakteri 6.7% 86.7% 6.7% 100.0%

  Crosstabulation Uji Kepekaan Enterobacteriaceae Penghasil ESBL Terhadap Meropenem

  K. pneumoniae Count

  1

  6

  7 % within spesies bakteri 14.3% 85.7% 0.0% 100.0%

  Enterobacter sp Count

  2

  2 % within spesies bakteri 0.0% 100.0% 0.0% 100.0%

  4

  I R S spesies bakteri E. coli

  2

  6 % within spesies bakteri 0.0% 66.7% 33.3% 100.0%

  Total Count

  1

  12

  2

  Count

  Cotrimoxazole Total

  Meropenem Total R S spesies bakteri

  1

  E. coli Count

  2

  5

  7 % within spesies bakteri 28.6% 71.4% 100.0%

  Enterobacter sp Count

  1

  2 % within spesies bakteri 50.0% 50.0% 100.0%

  Crosstabulation Uji Kepekaan Enterobacteriaceae Penghasil ESBL Terhadap Cotrimoxazole

  K. pneumoniae Count

  6

  6 % within spesies bakteri 0.0% 100.0% 100.0%

  Total Count

  3

  12

  15 % within spesies bakteri 20.0% 80.0% 100.0%

  15 % within spesies bakteri 6.7% 80.0% 13.3% 100.0%

  Enterobacteriaceae Penghasil ESBL Terhadap Cefotaxime Crosstabulation Uji Kepekaan

  Cefotaxime Total R

  Count

  7

  7 E. coli % within spesies bakteri 100.0% 100.0% Count

  2

  2 spesies bakteri Enterobacter sp % within spesies bakteri 100.0% 100.0% Count

  6

  6 K. pneumoniae % within spesies bakteri 100.0% 100.0% Count

  15

  15 Total % within spesies bakteri 100.0% 100.0%

  Crosstabulation Uji Kepekaan Enterobacteriaceae Penghasil ESBL Terhadap Cefepime

  Cefepime Total

  I R Count

  1

  6

  7 E. coli % within spesies bakteri 14.3% 85.7% 100.0% Count

  2

  2 spesies bakteri Enterobacter sp % within spesies bakteri 0.0% 100.0% 100.0% Count

  6

  6 K. pneumoniae % within spesies bakteri 0.0% 100.0% 100.0% Count

  1

  14

  15 Total % within spesies bakteri 6.7% 93.3% 100.0%

  Cross tabukation Pola Kepekaan Enterobacteriaceae terhadap Ciprofloxacin

  Ciprofloxacin Total R S

  Count

  7

  7 E. coli % within spesies bakteri 100.0% 0.0% 100.0% Count

  1

  1

  2 spesies bakteri Enterobacter sp % within spesies bakteri 50.0% 50.0% 100.0% Count

  5

  1

  6 K. pneumoniae % within spesies bakteri 83.3% 16.7% 100.0% Count

  13

  2

  15 Total % within spesies bakteri 86.7% 13.3% 100.0%

  Cross tabukation Pola Kepekaan Enterobacteriaceae terhadapNorfloxacin

  Norfloxacin Total

  I R S Count

  6

  1

  7 E. coli % within spesies bakteri 0.0% 85.7% 14.3% 100.0% Count

  1

  1

  2 spesies bakteri Enterobacter sp % within spesies bakteri 0.0% 50.0% 50.0% 100.0% Count

  1

  5

  6 K. pneumoniae % within spesies bakteri 16.7% 83.3% 0.0% 100.0% Count

  1

  12

  2

  15 Total % within spesies bakteri 6.7% 80.0% 13.3% 100.0%

  45 % within NamaBakteri 33.3% 66.7% 100.0%

  5 % within NamaBakteri 40.0% 60.0% 100.0%

  E. Coli Count

  7

  21

  28 % within NamaBakteri 25.0% 75.0% 100.0% Enterobacter sp. Count

  2

  3

  K. Pneumoniae Count

  Hasil skirining Enterobacteriaceae Penghasil ESBL dengan Metode Uji Double Disk Synergy

  6

  6

  12 % within NamaBakteri 50.0% 50.0% 100.0%

  Total Count

  15

  30

  hasilskrining Total

  15 % within spesies bakteri 80.0% 20.0% 100.0%

  Cross tabukation Pola Kepekaan Enterobacteriaceae terhadap Ofloxacin

  1

  Ofloxacin Total R S spesies bakteri

  E. coli Count

  6

  1

  7 % within spesies bakteri 85.7% 14.3% 100.0%

  Enterobacter sp Count

  1

  3

  2 % within spesies bakteri 50.0% 50.0% 100.0%

  K. pneumoniae Count

  5

  1

  6 % within spesies bakteri 83.3% 16.7% 100.0%

  Total Count

  12

  • NamaBakteri
Grafik Distribusi Frekuensi Bakteri Penyebab Infeksi Saluran Kemih

  Lampiran 4 Dokumentasi penelitian Beberapa foto hasil positif skrining Enterobacteriace penghasil ESBL dengan metode uji Double Disk Synergy

  Beberapa foto hasil negatif skrining Enterobacteriace penghasil ESBL dengan metode uji Double Disk Synergy

  Beberapa foto uji kepekaan Enterobacteriaceae penghasil ESBL terhadap berbagai golongan antibiotika

  Lampiran 5

  Lampiran 6