Hubungan Aiag Score Dengan Besar Varises Esofagus Secara Endoskopi Pada Penderita Sirosis Hati
57
Lampiran 1 : Surat Persetujuan Komite Etik
Universitas Sumatera Utara
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Lampiran 2
LEMBAR PENJELASAN KEPADA CALON SUBJEK PENELITIAN
Selamat pagi/ siang Bapak/ Ibu, pada hari ini saya, dr. Dedy Mhd,Abu
Bakar, peserta Pendidikan Pasca Sarjana Ilmu Penyakit Dalam/ Magister
Klinik FK-USU Medan akan melakukan penelitian yang berjudul ”Hubungan
Besar Varises Esofagus Secara Endoskopi dengan AIAG score pada Penderita
Sirosis Hati”.
Kepada Bapak/ Ibu yang bersedia mengikuti penelitian ini nantinya
akan diminta mengisi surat persetujuan ikut dalam penelitian, mengikuti
wawancara untuk mencari adanya hal-hal yang dapat mengganggu penelitian,
dan dilakukan pemeriksaan laboratorium berupa pemeriksaan darah sebanyak
15 cc (1 sendok makan) yang akan diambil dari lengan oleh ahli untuk menilai
sebuah skor yang disebut AIAG Score melalui parameter umur, INR, γGT, dan
albumin. Kemudian hasil skor tersebut akan saya bandingkan dengan hasil
pemeriksaan endoskopi.
Manfaat penelitian ini adalah dapat memberikan informasi tentang
adanya varises esofagus pada penderita sirosis hati serta meringankan biaya
pemeriksaan untuk pemantauan varises esofagus dan pemeriksaan menjadi
lebih sederhana, murah dan tidak membutuhkan waktu yang lama. Pada
penelitian ini tidak menimbulkan efek samping apapun, hanya risiko yang
dapat terjadi dari penelitian ini adalah terjadinya lebam setelah pengambilan
darah.
Setelah hasil akhir diperoleh, nantinya akan terlihat apakah terdapat
hubungan antara besar varises esofagus secara endoskopi dengan AIAG score.
Bila masih terdapat pertanyaan atau keluhan sewaktu penelitian ini berjalan,
maka Bapak/Ibu dapat menghubungi saya pada:
Nama
: dr. Dedy Mhd. Abu Bakar
Alamat
: Jl. Jl. Ekarasmi, gg. Ekarasmi I no. 15, Kec. Medan Johor, Medan
Telepon : 085350398750
Peneliti,
(dr. Dedy Mhd. Abu Bakar)
Universitas Sumatera Utara
59
Lampiran 3
SURAT PERSETUJUAN SETELAH PENJELASAN
(INFORMED CONSENT )
Saya yang bertanda tangan dibawah ini :
Nama
:...........................................................................................
Alamat
:...........................................................................................
Umur
:........................ Tahun
Jenis Kelamin : Laki-laki/ Perempuan*
No Telp/ HP
:
Setelah mendapat penjelasan dari peneliti tentang kebaikan dan keburukan
prosedur penelitian ini, menyatakan BERSEDIA ikut serta dalam penelitian
tentang ”Hubungan AIAG score dengan Besar Varises Esofagus Secara Endoskopi
pada Penderita Sirosis Hati”. Apabila sewaktu-waktu saya mengundurkan diri dari
penelitian ini, kepada saya tidak dituntut apapun.
Demikianlah surat persetujuan bersedia ikut dalam penelitian ini saya buat,
untuk dapat digunakan seperlunya.
Medan, ...........................2014
Yang memberi pernyataan,
(.............................................)
*Coret yang tidak perlu
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Lampiran 4
DATA PESERTA
Tanggal:
MR
:
No. Peserta
:
I. IDENTITAS PRIBADI
Nama
:
Tempat/ Tanggal lahir :
Jenis kelamin
: Laki-laki / Perempuan
Pendidikan terakhir
:
Pekerjaan
:
Status
: Kawin / Belum Kawin.
Faktor risiko
:
No. Telp/Hp
:
II. PEMERIKSAAN FISIK
III. PEMERIKSAAN LABORATORIUM
Parameter
Nilai
INR
γGT (U/L)
Albumin (g/dL)
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Lampiran 5
LEMBAR KUESIONER KEPATUHAN PENGOBATAN MORISKY-8
Nilai
No
Pertanyaan
Ya/ Tidak
(Ya=0,
Tidak=1)
1
Apakah anda terkadang lupa mengkonsumsi
obat ?
Pasien terkadang tidak mengkonsumsi obat
2
selain alasan lupa. Dalam 2 minggu terakhir,
apakah ada hari dimana anda tidak
mengkonsumsi obat ?
Pernahkah anda mengurangi atau menghenti-
3
kan obat tanpa sepengetahuan dokter karena
anda
merasa
tidak
nyaman
saat
mengkonsumsinya ?
4
5
6
Saat anda bepergian atau keluar rumah, apakah
anda kadang lupa mengkonsumsi obat ?
Apakah
anda
mengkonsumsi
obat
anda
semalam ?*
Saat anda merasa gejala anda sudah berkurang,
apakah anda berhenti mengkonsumsi obat ?
Mengkonsumsi obat setiap hari merupakan
7
ketidaknyamanan bagi beberapa orang. Apakah
anda merasa jenuh dengan pengobatan anda ?
Seberapa
8
sering
anda
kesulitan
untuk
mengingat mengkonsumsi obat anda ?
A. Tidak pernah/ Jarang
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B. Sekali-sekali
C. Kadang-kadang
D. Sering
E. Setiap saat
A= 1; B-E= 0
TOTAL NILAI
* Untuk no.5 bila jawaban Ya= 1, Tidak= 0
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Lampiran 6
DAFTAR RIWAYAT HIDUP
I.
Identitas Pribadi
Nama
: dr. Dedy Muhammad Abu Bakar
Tempat/Tgl Lahir : Padangsidimpuan/ 28 Februari 1979
Suku/Bangsa
: Mandailing / Indonesia
Agama
: Islam
Alamat
: Jl. Ekarasmi, gg.Ekarasmi I no.15, Kec. Medan
Johor, Medan
II.
Pendidikan
SD Negeri 15 Padangsidimpuan
Tamat Tahun 1992
SMP Negeri 1 Padangsidimpuan
Tamat Tahun 1995
SMU Negeri 1 Padangsidimpuan
Tamat Tahun 1998
FK Universitas Syiah Kuala
Tamat Tahun 2006
III.
Riwayat Pekerjaan
PNS RSUD Panyabungan tahun 2009-sekarang
IV.
Perkumpulan Profesi
IDI Cabang Panyabungan
PAPDI Sumatera Utara
V.
Journal Reading
1. Takikawa Y, Ryujin Endo, Suzuki K, Tsubouchi H. Early
prediction of short-term development of hepatic encephalopathy in
patient with acute liver disease unrelated to paracetamol. A
prospective study in Japan. Journal of Hepatology. 2009;58:1021–
1029.
2. Mahesh Kumar Goenka, Majumder S, Pradeepta Kumar Sethy,
Chakraborty M. Helicobacter pylori, negative-steroidal anti-
Universitas Sumatera Utara
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inflamatory drug-negative peptic ulcer in India. Indian J
Gastroenterol. 2011;30(1):33-37.
3. Sergio A.Gonzales, Forcada P, Inserra F, Obregon S, Olano D.
Sodium intake is associated with parasympathetic tone and
metabolic parameters in mild hypertension. American Journal of
Hypertension. 2012;25(1):620-624.
4. Ch. Venkata Rama Krishna, P.V.L.N. Srinivasa Rao, V. Siva
Kumar. Acute renal failure in falciparum malaria: Clinical
characteristics, demonstration of oxidative stress, and
prognostication. Saudi J Kidney Dis Transpl. 2012:23(2):296-300.
5. Perluigi Tricoci, M.D., Ph.D., Zhen Huang, M.S., Claes Held,
M.D., Ph.D., et.al. Thrombin-receptor antsgonist vorapaxar in acute
coronary syndromes. N Engl J Med. 2012;366:20-23.
6. Byron s. Kennedy, M.D., Ph.D., M.P.H., Brenden Bedard, M.P.H.,
Mary Younge R.N., et.al. Outbreak of mycobacterium chelonae in
infection associated with tatto ink. N Engl J Med. 2012;367:10201024.
7. Siti Nurleila, Din Syafruddin, Iqbal R.F. Elyazar, Baird K. Serious
and fatal illlness associated with falciparum amd vivax malaria
among patient admitted to hospital at West Sumba in Eastern
Indonesia. Am J Trop Med Hyg. 2012;87(1):41-49.
8. Mehmet Gunduz, Ercan Gundus, Kircelli F, okur N, Ozkaya M.
Role of surrogate of atherosclerosis in clinical and subclinical
thyroidism. International Journal of Endocrinology. 2012.
9. Catherine Pihiker, M.D., Barbara Linder, MD, Ph.D., Dana
dabelea, M.D., Ph.D., et.al. Insulin regimens and clinical outcome
in a type 1 diabetes cohort. Diabetes care. 2012;36:27-33.
10. Ilhami Berber, halit Diri, Mehmet Ali Erkurt, et.al. Evaluation of
ferric and ferrous iron therapies in womwn with iron deficiency
anaemia. Hindawi Advance in Hematology. 2014.
11. Thomas F. Imperiale, M.D., David F. Ranso hoff, M.D., Steven H.
Itzkowits, M.D., et.al. Multitarget stool DNA testing for colorectalcancer screening. N Engl J Med. 2014;370:1287-1297.
12. Ryo Oda, Fujiwara H, Tokunaga D, Nakamura S, et.al. How do
anti_TNF therapies affect gait finction in patients with rheumatoid
arthritis International journal of Reumatic Diseases, 2014;17:57-62.
13. Takashi Abe, Ph.D, Jeremy P. Loenneke, Ph.D, Tetsuo Fukunaga,
Ph.D. Interrelationship between bosymass to waist circumference
ratio, body mass inde, and total body muscularity in older women.
Journal of Clinical Gerontology. 2014;58-64.
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14. Chih-hsin Lee, Ming-Chia Lee, Hsien-Ho Lin, et.al. Pulmonary
Tuberculosis and delay in anti-tuberculous treatment are important
risk factors for chronic obstructive pulmonary disease. Plos ONE
2012;7(5).
15. Abdussalam M Alaithan, Javed I Memon, Rifat S Rehmani, et.al.
Chronic obstructive pulmonary disease: hospital and intensive care
unit in kingdom of Saudi Arabia. International Journal of COPD.
2012;7:819-823.
16. K. Kontogianni, P. Bakakos, G. Hillas, et.al. Level of prostaglandin
E-2 and cysteinyl-leukotrienes in sputum supernatant of patients
with asthma: the effect of smoking. Clinical & Experimental
Allergy. 2012;43:616-624.
17. R.Soundravally, S.L. Hoti, Shripad A. Patil, et.al. Association
between proinflamatory cytokines and lipid peroxidation in patients
with severe dengue disease around defervescence. Intenational
Journal of Infectious disease.2014;18:68-72.
VI.
Tulisan Ilmiah di Departemen Ilmu Penyakit Dalam
1. Thrombotic Thrombocypenic Purpura dan Hemolitic Uremic
Syndrome
2. Gangguan Somatisasi
3. Gangguan hati padan HIV
4. Nocturnal Hemodialysis
5. Hipertiroidisme pada mola hidatidosa
6. Cardiomyopathy
7. Tumor Mediastinum
VII.
1.
2.
Publikasi Ilmiah
Abu Bakar DM., Realsyah T, Safri Z, Hasan R. Endokarditis
Infektif: Laporan kasus. Kongres Nasional XV Perhimpunan
Dokter Spesialis Penyakit Dalam Indonesia, KOPAPDI XV,
Medan, 2012.
Abu Bakar DM, Ginting F, Ginting Y. Hubungan perubahan kadar
hemoglobin dengan kadar CD4 pada pasien HIV yang diterapi
dengan ARV selama 6 bulan: KONAS PETRI XIX & PKWI XVI,
Makassar, 2013
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VIII.
Partisipasi Dalam Kegiatan Ilmiah
1. Peserta Kursus “General Life Support”: RSUP.HAM. Medan, Mei
2009.
2. Peserta Simposium “Respiratory Evidenced and Respiratory
Competence Synergy on Clinical Practice”. MERCY 2010. Medan,
19-21 Maret 2010.
3. Peserta Simposium “Current Management in Internal Medicine”.
11th Annual Scientific Meeting Internal Medicine. Medan, 1-3 April
2010.
4. Peserta Simposium “Update on Diabetes Management and Medical
Nutrition Therapy”. PAPDI. Medan, 17 April 2010.
5. Peserta Simposium “Pemenuhan Gizi Seimbang dengan Susu UHT”.
IDI. Medan, 31 Juli 2010.
6. Peserta Simposium “Recent Advances on Management of Secondary
Ischemic Stroke Prevention”. PERDOSSI. Medan, 27 November
2010.
7. Peserta Kursus “Advanced Electrocardiography (ECG)”. PERKI.
Medan 10-11 Desember 2010.
8. Peserta Workshop “Medical Skill Upgrade Cardio-Metabolic”.
PAPDI. Medan 2 April 2011.
9. Peserta Simposium “Clinical Rheumatology in Daily Practice”.
Rheumatology Update 2011. Medan, 9-10 Juli 2011.
10. Peserta Simposium “Patophysiology and Recent Management of
Chronic Constipation and Acute Diarrhea”. The Indonesian Society
of Gastroenterology. Medan, 13 November 2011.
11. Peserta Simposium “The New Option of Insulin Resistance
Treatment in Type 2 Diabetes”. PERKENI. Medan, 20 November
2011.
12. Peserta Free Paper Poster Presentation “Kongres Nasional XV
Perhimpunan Dokter Spesialis Penyakit Dalam Indonesia
(KOPAPDI XV)”, Medan, 12-15 Desember 2012.
13. Peserta Workshop “Diabetes Update for Excellent”. PERKENI.
Medan, 17 Maret 2012.
14. Peserta Simposium “A New Novel DPP-4 Inhibitor for T2DM
Treatment”. PERKENI. Medan, 1 April 2012.
15. Peserta Simposium “Diabetic Neuropathy”. PERKENI. Medan, 8
September 2012.
16. Peserta Workshop “Terapi Insulin”. Dies Natalis 60 FK-USU.
Medan, 11 September 2012.
17. Peserta Simposium “Right from The Start: An Urgent Concern”.
FEDS-5. Medan, 23 Februari 2013.
18. Peserta Workshop “Managing Diabetes Mellitus: From A to Z”.
Jeanne Latu Conference, 2 Maret 2013.
Universitas Sumatera Utara
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19. Peserta Simposium “Recent Management in Helicobacter pylori
Infection, Irritable Bowel Syndrome and Hepatic Encephalopathy”.
PPHI. Medan, 20 April 2013.
20. Peserta Pelatihan Program Pengembangan Pendidikan Keprofesian
Berkelanjutan Ultrasonografi Tahap Satu bagi Spesialis dan PPDS
Penyakit Dalam. Departemen Penyakit Dalam FK USU dan PUSKI.
Medan, 15-18 April 2013.
21. Peserta Simposium “Current and Future Treatment in Diabetes
Management”. PERKENI. Medan, 11 Mei 2013.
22. Peserta Kursus “Diabetes Camp 2013”. PERSADIA. Berastagi, 1819 Mei 2013.
23. Peserta Kursus “Partnership for Diabetes Control in Indonesia”.
PERKENI. Medan, 7-9 Juni 2013.
24. Peserta Simposium “Linagliptin: A Novel Unique DPP IV Inhibitor”.
PAPDI. Medan, 11 Juni 2013.
Universitas Sumatera Utara
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Lampiran 7
HASIL STATISTIK
Frequency Table
Jk
Frequency
Valid
Percent
Valid Percent
Cumulative Percent
laki-laki
60
75,0
75,0
75,0
perempuan
20
25,0
25,0
100,0
Total
80
100,0
100,0
Asites
Frequency
Percent
6
7,5
7,5
7,5
Minimal
25
31,3
31,3
38,8
Sedang
40
50,0
50,0
88,8
Berat
9
11,3
11,3
100,0
Total
80
100,0
100,0
Valid tidak ada
Valid Percent
Cumulative Percent
HE
Frequency Percent
Valid
Tidak ada
Valid Percent Cumulative Percent
77
96,3
96,3
96,3
HE grade 1
1
1,3
1,3
97,5
HE grade 2
2
2,5
2,5
100,0
80
100,0
100,0
Total
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CP
Frequency Percent Valid Percent Cumulative Percent
Valid
A (ringan)
16
20,0
20,0
20,0
B (sedang)
28
35,0
35,0
55,0
C (berat)
36
45,0
45,0
100,0
Total
80
100,0
100,0
EtioSH
Frequency Percent
Valid
Valid Percent
Cumulative Percent
Bukan Hep B dan C
34
42,5
42,5
42,5
Hepatitis B
40
50,0
50,0
92,5
Hepatitis C
5
6,3
6,3
98,8
Hep. B dan C
1
1,3
1,3
100,0
Total
80
100,0
100,0
Diameter VE
Frequency Percent
Valid
Valid Percent
Cumulative Percent
F1
40
50,0
50,0
50,0
F2
29
36,3
36,3
86,3
F3
11
13,8
13,8
100,0
Total
80
100,0
100,0
Ukuran Varises Esofagus
requency
Valid
Percent
Valid Percent
Cumulative Percent
Kecil
40
50,0
50,0
50,0
Besar
40
50,0
50,0
100,0
Total
80
100,0
100,0
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Case Processing Summary
Cases
Valid
umur
Missing
Total
N
Percent
N
Percent
N
Percent
80
100,0%
0
0,0%
80
100,0%
Descriptives
Statistic
umur
Mean
51,55
95% Confidence Interval
Lower Bound
49,05
for Mean
Upper Bound
54,05
5% Trimmed Mean
51,25
Median
51,50
Variance
126,504
Std. Deviation
11,247
Minimum
23
Maximum
88
Range
65
Interquartile Range
15
Std. Error
1,257
Skewness
,488
,269
Kurtosis
,768
,532
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Crosstabs
Case Processing Summary
Cases
Valid
N
Percent
Missing
N
Total
Percent
N
Percent
jk * Ukuran Varises Esofagus
80
100,0%
0
0,0%
80
100,0%
Asites * Ukuran Varises Esofagus
80
100,0%
0
0,0%
80
100,0%
HE * Ukuran Varises Esofagus
80
100,0%
0
0,0%
80
100,0%
CP * Ukuran Varises Esofagus
80
100,0%
0
0,0%
80
100,0%
EtioSH * Ukuran Varises Esofagus
80
100,0%
0
0,0%
80
100,0%
jk * Ukuran Varises Esofagus
Crosstab
Ukuran Varises Esofagus
Kecil
laki-laki
Count
Expected Count
% within jk
% within Ukuran Varises
Esofagus
perempuan
Count
Expected Count
% within jk
% within Ukuran Varises
Esofagus
Total
Count
Expected Count
% within jk
% within Ukuran Varises
Esofagus
Besar
Total
30
30
60
30,0
30,0
60,0
50,0%
50,0%
100,0%
75,0%
75,0%
75,0%
10
10
20
10,0
10,0
20,0
50,0%
50,0%
100,0%
25,0%
25,0%
25,0%
40
40
80
40,0
40,0
80,0
50,0%
50,0%
100,0%
100,0%
100,0%
100,0%
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Chi-Square Tests
Asymp. Sig.
Value
Pearson Chi-Square
Continuity Correction
df
Likelihood Ratio
.
1
1,000
,000
1
1,000
,000
1
1,000
,000
b
(2-sided)
a
Fisher's Exact Test
Exact Sig
Exact Sig.
(2-sided)
(1-sided)
1,000
Linear-by-Linear Association
,000
N of Valid Cases
1
,602
1,000
80
a. 0 cells (0,0%) have expected count less than 5. The minimum expected count is 10,00.
Computed only for a 2x2 table
Risk Estimate
95% Confidence Interval
Value
Odds Ratio for jk (laki-laki /
perempuan)
For cohort Ukuran Varises
Esofagus = Kecil
For cohort Ukuran Varises
Esofagus = Besar
N of Valid Cases
Lower
Upper
1,000
,363
2,751
1,000
,603
1,659
1,000
,603
1,659
80
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Asites * Ukuran Varises Esofagus
Crosstab
Ukuran Varises Esofagus
Kecil
Asites
tidak ada
Count
1
6
Expected Count
3,0
3,0
6,0
% within Asites
83,3%
16,7%
100,0%
12,5%
2,5%
7,5%
20
5
25
Expected Count
12,5
12,5
25,0
% within Asites
80,0%
20,0%
100,0%
50,0%
12,5%
31,3%
15
25
40
Expected Count
20,0
20,0
40,0
% within Asites
37,5%
62,5%
100,0%
37,5%
62,5%
50,0%
0
9
9
Expected Count
4,5
4,5
9,0
% within Asites
0,0%
100,0%
100,0%
0,0%
22,5%
11,3%
40
40
80
Expected Count
40,0
40,0
80,0
% within Asites
50,0%
50,0%
100,0%
100,0%
100,0%
100,0%
Esofagus
Count
% within Ukuran Varises
Esofagus
sedang
Count
% within Ukuran Varises
Esofagus
berat
Count
% within Ukuran Varises
Esofagus
Total
Total
5
% within Ukuran Varises
minimal
Besar
Count
% within Ukuran Varises
Esofagus
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Chi-Square Tests
Asymp. Sig. (2Value
df
sided)
a
3
,000
Likelihood Ratio
27,552
3
,000
Linear-by-Linear Association
20,979
1
,000
Pearson Chi-Square
23,167
N of Valid Cases
80
a. 4 cells (50,0%) have expected count less than 5. The minimum
expected count is 3,00.
Risk Estimate
Value
Odds Ratio for Asites (tidak
a
ada / minimal)
a. Risk Estimate statistics cannot be computed. They
are only computed for a 2*2 table without empty cells.
HE * Ukuran Varises Esofagus
Crosstab
Ukuran Varises Esofagus
Kecil
HE
Tidak ada
Count
Total
40
37
77
38,5
38,5
77,0
51,9%
48,1%
100,0%
100,0%
92,5%
96,3%
Count
0
1
1
Expected Count
,5
,5
1,0
0,0%
100,0%
100,0%
0,0%
2,5%
1,3%
Expected Count
% within HE
% within Ukuran Varises
Esofagus
HE grade 1
Besar
% within HE
% within Ukuran Varises
Esofagus
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E grade 2
Count
Expected Count
% within HE
% within Ukuran Varises
Esofagus
Total
Count
Expected Count
% within HE
% within Ukuran Varises
Esofagus
0
2
2
1,0
1,0
2,0
0,0%
100,0%
100,0%
0,0%
5,0%
2,5%
40
40
80
40,0
40,0
80,0
50,0%
50,0%
100,0%
100,0%
100,0%
100,0%
Chi-Square Tests
A symp. Sig
Value
df
(2-sided)
a
2
,210
Likelihood Ratio
4,276
2
,118
Linear-by-Linear Association
2,842
1
,092
Pearson Chi-Square
N of Valid Cases
3,117
80
a. 4 cells (66,7%) have expected count less than 5. The minimum
expected count is ,50.
Risk Estimate
Value
Odds Ratio for HE (Tidak
a
ada / HE grade 1)
a. Risk Estimate statistics cannot be computed.
They are only computed for a 2*2 table without empty
cells.
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CP * Ukuran Varises Esofagus
Crosstab
Ukuran Varises Esofagus
Kecil
CP
A (ringan)
16
0
16
Expected Count
8,0
8,0
16,0
100,0%
0,0%
100,0%
40,0%
0,0%
20,0%
16
12
28
14,0
14,0
28,0
57,1%
42,9%
100,0%
40,0%
30,0%
35,0%
8
28
36
18,0
18,0
36,0
22,2%
77,8%
100,0%
20,0%
70,0%
45,0%
40
40
80
40,0
40,0
80,0
50,0%
50,0%
100,0%
100,0%
100,0%
100,0%
% within Ukuran Varises
Esofagus
Count
Expected Count
% within CP
% within Ukuran Varises
Esofagus
C (berat)
Count
Expected Count
% within CP
% within Ukuran Varises
Esofagus
Total
Total
Count
% within CP
B (sedang)
Besar
Count
Expected Count
% within CP
% within Ukuran Varises
Esofagus
Chi-Square Tests
Asymp. Sig.
Value
df
(2-sided)
a
2
,000
Likelihood Ratio
34,522
2
,000
Linear-by-Linear Association
27,230
1
,000
Pearson Chi-Square
N of Valid Cases
27,683
80
0 cells (0,0%) have expected count less than 5. The minimum expected
count is 8,00.
Universitas Sumatera Utara
77
Risk Estimate
Value
Odds Ratio for CP (A (ringan) / B
a
(sedang))
a Risk Estimate statistics cannot be computed. They are
only computed for a 2*2 table without empty cells.
EtioSH * Ukuran Varises Esofagus
Crosstab
Ukuran Varises Esofagus
Kecil
EtioSH
Bukan Hep B dan C
Hepatitis B
Hepatitis C
Hep. B dan C
Total
Count
Besar
Total
22
12
34
Expected Count
17,0
17,0
34,0
% within EtioSH
64,7%
35,3%
100,0%
% within Ukuran Varises Esofagus
55,0%
30,0%
42,5%
15
25
40
Expected Count
20,0
20,0
40,0
% within EtioSH
37,5%
62,5%
100,0%
% within Ukuran Varises Esofagus
37,5%
62,5%
50,0%
3
2
5
Expected Count
2,5
2,5
5,0
% within EtioSH
60,0%
40,0%
100,0%
% within Ukuran Varises Esofagus
7,5%
5,0%
6,3%
Count
0
1
1
Expected Count
,5
,5
1,0
% within EtioSH
0,0%
100,0%
100,0%
% within Ukuran Varises Esofagus
0,0%
2,5%
1,3%
40
40
80
Expected Count
40,0
40,0
80,0
% within EtioSH
50,0%
50,0%
100,0%
% within Ukuran Varises Esofagus
100,0%
100,0%
100,0%
Count
Count
Count
Universitas Sumatera Utara
78
Chi-Square Tests
Asymp. Sig. (2Value
df
sided)
a
3
,084
Likelihood Ratio
7,099
3
,069
Linear-by-Linear Association
3,526
1
,060
Pearson Chi-Square
6,641
N of Valid Cases
80
4 cells (50,0%) have expected count less than 5. The minimum expected
count is ,50.
Risk Estimate
Value
Odds Ratio for EtioSH (Bukan Hep
a
B dan C / Hepatitis B)
Risk Estimate statistics cannot be computed.
They are only computed for a 2*2 table without
empty cells.
Case Processing Summary
Cases
Ukuran Varises Esofagus
Valid
N
umur
Missing
Percent
N
Total
Percent
N
Percent
Kecil
40
100,0%
0
0,0%
40
100,0%
Besar
40
100,0%
0
0,0%
40
100,0%
Descriptives
Ukuran Varises Esofagus
umur
Kecil
Statistic
Mean
52,53
95% Confidence Interval for
Lower Bound
48,30
Mean
Upper Bound
56,75
5% Trimmed Mean
52,19
Median
52,00
td. Error
2,091
Universitas Sumatera Utara
79
Variance
174,820
Std. Deviation
13,222
Minimum
23
Maximum
88
Range
65
Interquartile Range
17
Besar
Skewness
,369
,374
Kurtosis
,419
,733
Mean
50,58
1,410
95% Confidence Interval
Lower Bound
47,72
for Mean
Upper Bound
53,43
5% Trimmed Mean
50,33
Median
50,00
Variance
79,481
Std. Deviation
8,915
Minimum
33
Maximum
72
Range
39
Interquartile Range
14
Skewness
,417
,374
Kurtosis
-,068
,733
Tests of Normality
Kolmogorov-Smirnov
Ukuran Varises Esofagus
umur
Kecil
Besar
Statistic
,068
,093
df
40
40
a
Shapiro-Wilk
Sig.
Statistic Df
Sig.
,200
*
,988
40
,945
,200
*
,978
40
,630
*. This is a lower bound of the true significance.
a. Lilliefors Significance Correction
Universitas Sumatera Utara
80
T-Test
Group Statistics
Ukuran Varises Esofagus
umur
N
Mean
Std. Deviation
Std. Error Mean
Kecil
40
52,53
13,222
2,091
Besar
40
50,58
8,915
1,410
Independent Samples Test
evene's Test
for Equality of
Variances
t-test for Equality of Means
95% Confidence
Mean
Differen
ce
F
umur Equal variances
assumed
4,055
Sig.
,047
Equal variances
not assumed
t
Df
Std. Error
Interval of the
Difference
Difference
Sig. (2-tailed)
Lower
Upper
,773
78
,442
1,950
2,521
-3,070
6,970
,773
68,388
,442
1,950
2,521
-3,081
6,981
Case Processing Summary
Cases
Ukuran
Valid
Varises Esofagus
N
PLT, ribu/ul
Billirubin Total, mg/dl
AST, unit/L
Albumin, g/L
INR
Missing
Percent
N
Total
Percent
N
Percent
Kecil
40
100,0%
0
0,0%
40
100,0%
Besar
40
100,0%
0
0,0%
40
100,0%
Kecil
40
100,0%
0
0,0%
40
100,0%
Besar
40
100,0%
0
0,0%
40
100,0%
Kecil
40
100,0%
0
0,0%
40
100,0%
Besar
40
100,0%
0
0,0%
40
100,0%
Kecil
40
100,0%
0
0,0%
40
100,0%
Besar
40
100,0%
0
0,0%
40
100,0%
Kecil
40
100,0%
0
0,0%
40
100,0%
Universitas Sumatera Utara
81
ALT, mg/dl
Gamma GT, UI/L
AIAG Score
Besar
40
100,0%
0
0,0%
40
100,0%
Kecil
40
100,0%
0
0,0%
40
100,0%
Besar
40
100,0%
0
0,0%
40
100,0%
Kecil
40
100,0%
0
0,0%
40
100,0%
Besar
40
100,0%
0
0,0%
40
100,0%
Kecil
40
100,0%
0
0,0%
40
100,0%
Besar
40
100,0%
0
0,0%
40
100,0%
Descriptives
Ukuran Varises Esofagus
PLT, ribu/ul
Kecil
Statistic
Mean
242,45
95 % Confidence Interval for
Lower Bound
193,31
Mean
Upper Bound
291,59
5% Trimmed Mean
227,64
Median
201,50
Variance
24,297
23613,023
Std. Deviation
Besar
Std. Error
153,665
Minimum
56
Maximum
715
Range
659
Interquartile Range
215
Skewness
1,286
,374
Kurtosis
1,922
,733
Mean
111,70
12,811
95% Confidence Interval for Lower Bound
Mean
Upper Bound
85,79
137,61
5% Trimmed Mean
101,83
Median
83,00
Variance
Std. Deviation
6564,574
81,022
Minimum
23
Maximum
406
Range
383
Interquartile Range
66
Universitas Sumatera Utara
82
Billirubin Total, mg/dl
Kecil
Besar
AST, unit/L
Kecil
Skewness
2,040
,374
Kurtosis
4,547
,733
Mean
5,1420
1,30211
95% Confidence Interval for
Lower Bound
2,5082
Mean
Upper Bound
7,7758
5% Trimmed Mean
4,0386
Median
1,3050
Variance
67,820
Std. Deviation
8,23529
Minimum
,10
Maximum
32,49
Range
32,39
Interquartile Range
4,79
Skewness
2,032
,374
Kurtosis
3,331
,733
Mean
7,0550
1,31137
95% Confidence Interval for
Lower Bound
4,4025
Mean
Upper Bound
9,7075
5% Trimmed Mean
6,0286
Median
3,7450
Variance
68,788
Std. Deviation
8,29383
Minimum
,62
Maximum
32,18
Range
31,56
Interquartile Range
8,31
Skewness
1,916
,374
Kurtosis
3,132
,733
Mean
94,68
18,124
95% Confidence Interval for Lower Bound
Mean
Upper Bound
58,02
131,33
5% Trimmed Mean
78,22
Median
49,50
Variance
Std. Deviation
13138,533
114,623
Minimum
12
Maximum
489
Universitas Sumatera Utara
83
Besar
Range
477
Interquartile Range
64
Skewness
2,276
,374
Kurtosis
4,800
,733
Mean
178,80
34,234
95% Confidence Interval for
Lower Bound
109,55
Mean
Upper Bound
248,05
5% Trimmed Mean
147,47
Median
105,00
Variance
46879,138
Std. Deviation
Albumin, g/L
Kecil
Besar
216,516
Minimum
18
Maximum
1075
Range
1057
Interquartile Range
132
Skewness
2,555
,374
Kurtosis
7,383
,733
Mean
2,755
,1003
95% Confidence Interval for
Lower Bound
2,552
Mean
Upper Bound
2,958
5% Trimmed Mean
2,703
Median
2,750
Variance
,402
Std. Deviation
,6341
Minimum
1,7
Maximum
4,9
Range
3,2
Interquartile Range
,7
Skewness
1,261
,374
Kurtosis
3,245
,733
Mean
2,218
,0949
95% Confidence Interval for Lower Bound
Mean
Upper Bound
2,025
2,410
5% Trimmed Mean
2,217
Median
2,100
Variance
,360
Std. Deviation
,6004
Universitas Sumatera Utara
84
INR
Kecil
Minimum
,5
Maximum
3,8
Range
3,3
Interquartile Range
,8
Skewness
,067
,374
Kurtosis
1,134
,733
Mean
1,4233
,19979
95% Confidence Interval for Lower Bound
Mean
Upper Bound
1,2383
Median
1,1750
Variance
1,597
1,26357
Minimum
,56
Maximum
9,00
Range
8,44
Interquartile Range
,42
Skewness
5,798
,374
Kurtosis
35,435
,733
Mean
1,6188
,07156
95% Confidence Interval for Lower Bound
Mean
Upper Bound
1,7635
1,5661
Median
1,4900
,205
Std. Deviation
Kecil
1,4740
5% Trimmed Mean
Variance
ALT, mg/dl
1,8274
5% Trimmed Mean
Std. Deviation
Besar
1,0191
,45256
Minimum
1,14
Maximum
3,33
Range
2,19
Interquartile Range
,47
Skewness
1,850
,374
Kurtosis
4,499
,733
Mean
52,88
9,847
95% Confidence Interval for Lower Bound
Mean
Upper Bound
32,96
72,79
5% Trimmed Mean
44,53
Median
29,00
Universitas Sumatera Utara
85
Variance
3878,676
Std. Deviation
Besar
62,279
Minimum
8
Maximum
346
Range
338
Interquartile Range
41
Skewness
3,045
,374
Kurtosis
11,992
,733
Mean
58,25
6,884
95% Confidence Interval for
Lower Bound
44,33
Mean
Upper Bound
72,17
5% Trimmed Mean
53,58
Median
48,00
Variance
1895,577
Std. Deviation
Gamma GT, UI/L
Kecil
43,538
Minimum
9
Maximum
236
Range
227
Interquartile Range
35
Skewness
2,130
,374
Kurtosis
6,146
,733
Mean
111,05
19,970
95% Confidence Interval for Lower Bound
Mean
Upper Bound
151,44
5% Trimmed Mean
96,33
Median
51,00
Variance
15952,254
Std. Deviation
Besar
70,66
126,302
Minimum
6
Maximum
530
Range
524
Interquartile Range
159
Skewness
1,679
,374
Kurtosis
2,496
,733
Mean
207,13
40,137
95% Confidence Interval for Lower Bound
Mean
Upper Bound
125,94
288,31
Universitas Sumatera Utara
86
5% Trimmed Mean
177,06
Median
68,00
Variance
Std. Deviation
AIAG Score
Kecil
253,849
Minimum
8
Maximum
991
Range
983
Interquartile Range
297
Skewness
1,631
,374
Kurtosis
1,982
,733
Mean
,89936575 ,025083833
95% Confidence Interval for
Lower Bound ,84862891
Mean
Upper Bound ,95010259
5% Trimmed Mean
,92190056
Median
,95660500
Variance
Std. Deviation
Besar
64439,497
,025
,158644087
Minimum
,123900
Maximum
,999980
Range
,876080
Interquartile Range
,124058
Skewness
-3,329
,374
Kurtosis
14,299
,733
Mean
,99633625 ,000878720
95% Confidence Interval for Lower Bound ,99455887
Mean
Upper Bound ,99811363
5% Trimmed Mean
,99706139
Median
,99898500
Variance
Std. Deviation
,000
,005557516
Minimum
,977860
Maximum
,999990
Range
,022130
Interquartile Range
,004328
Skewness
-2,013
,374
Kurtosis
3,527
,733
Universitas Sumatera Utara
87
Tests of Normality
Kolmogorov-Smirnov
Ukuran Varises Esofagus
PLT, ribu/ul
Billirubin Total, mg/dl
AST, unit/L
Albumin, g/L
INR
ALT, mg/dl
Gamma GT, UI/L
AIAG Score
Statistic
df
a
Sig.
Shapiro-Wilk
Statistic
df
Sig.
Kecil
,127
40
,103
,887
40
,001
Besar
,211
40
,000
,781
40
,000
Kecil
,354
40
,000
,642
40
,000
Besar
,228
40
,000
,733
40
,000
Kecil
,277
40
,000
,668
40
,000
Besar
,275
40
,000
,682
40
,000
Kecil
,160
40
,012
,901
40
,002
Besar
,178
40
,003
,955
40
,110
Kecil
,340
40
,000
,331
40
,000
Besar
,161
40
,011
,829
40
,000
Kecil
,263
40
,000
,648
40
,000
Besar
,204
40
,000
,803
40
,000
Kecil
,238
40
,000
,777
40
,000
Besar
,297
40
,000
,740
40
,000
Kecil
,263
40
,000
,628
40
,000
Besar
,255
40
,000
,696
40
,000
a. Lilliefors Significance Correction
Mann-Whitney Test
Ranks
Ukuran Varises Esofagus
PLT, ribu/ul
Billirubin Total, mg/dl
AST, unit/L
N
Mean Rank Sum of Ranks
Kecil
40
52,68
2107,00
Besar
40
28,33
1133,00
Total
80
Kecil
40
33,34
1333,50
Besar
40
47,66
1906,50
Total
80
Kecil
40
33,10
1324,00
Universitas Sumatera Utara
88
Albumin, g/L
INR
ALT, mg/dl
Gamma GT, UI/L
AIAG Score
PLT, ribu/ul
Besar
40
47,90
1916,00
Total
80
Kecil
40
49,85
1994,00
Besar
40
31,15
1246,00
Total
80
Kecil
40
29,24
1169,50
Besar
40
51,76
2070,50
Total
80
Kecil
40
35,23
1409,00
Besar
40
45,78
1831,00
Total
80
Kecil
40
35,41
1416,50
Besar
40
45,59
1823,50
Total
80
Kecil
40
26,40
1056,00
Besar
40
54,60
2184,00
Total
80
Billirubin Total, mg/dl AST, unit/L
Albumin, g/L
INR
Mann-Whitney U
313,000
513,500
504,000
426,000
349,500
Wilcoxon W
1133,000
1333,500
1324,000
1246,000
1169,500
-4,686
-2,757
-2,849
-3,608
-4,336
,000
,006
,004
,000
,000
Asymp. Sig. (2-tailed)
ALT, mg/dl
Gamma GT, UI/L
AIAG Score
Mann-Whitney U
589,000
596,500
236,000
Wilcoxon W
1409,000
1416,500
1056,000
-2,031
-1,958
-5,430
,042
,050
,000
Asymp. Sig. (2-tailed)
Universitas Sumatera Utara
89
ROC Curve
Notes
Output Created
31-JUL-2016 09:54:37
Comments
Input
Data
:PROJECT\STATISTIK\PENY
DALAM\DEDDY\data 31 Juli 2016\data dr
Dedy Interna.sav
Active Dataset
DataSet1
Filter
Weight
Split File
N of Rows in Working Data File
Missing Value
Definition of Missing
Handling
80
User-defined missing values
are treated as missing.
Cases Used
Statistics are based on all cases
with valid
data for all variables in the analysis.
Syntax
ROC AIAG BY ROCGroup (1)
/PLOT=CURVE(REFERENCE)
/PRINT=SE COORDINATES
/CRITERIA=CUTOFF(INCLUDE)
TESTPOS(LARGE)
DISTRIBUTION(FREE) CI(95)
/MISSING=EXCLUDE.
Resources
Processor Time
00:00:00,27
Elapsed Time
00:00:00,24
Case Processing Summary
Ukuran
Varises Esofagus
Valid N (listwise)
a
40
Negative
40
Positive
Larger values of the test result variable(s) indicate
stronger evidence for a positive actual state.
a. The positive actual state is VE Besar.
Universitas Sumatera Utara
90
Area Under the Curve
Test Result Variable(s): AIAG Score
Area
Std. Error
a
symptotic Sig.
b
Asymptotic 95% Confidence Interval
Lower Bound
,853
,044
,000
a.
Under the nonparametric assumption
b.
Null hypothesis: true area = 0.5
Upper Bound
,766
,939
Universitas Sumatera Utara
91
Coordinates of the Curve
Test Result Variable(s): AIAG Score
Positive if Greater Than
Or Equal To
a
Sensitivity
1 - Specificity
,00000000
1,000
1,000
,39314500
1,000
,975
,67206000
1,000
,950
,69134500
1,000
,925
,70428000
1,000
,900
,75376000
1,000
,875
,80025500
1,000
,850
,80418000
1,000
,825
,83699500
1,000
,800
,86703000
1,000
,775
,87196000
1,000
,750
,87842000
1,000
,725
,89095500
1,000
,700
,91012000
1,000
,675
,92098000
1,000
,650
,92589000
1,000
,625
,92956000
1,000
,600
,93523000
1,000
,575
,94415000
1,000
,550
,95067000
1,000
,525
,95660500
1,000
,500
,96129500
1,000
,475
,96480500
1,000
,450
,96959000
1,000
,425
,97372000
1,000
,400
,97620000
1,000
,375
,97753000
1,000
,350
,97963000
,975
,350
,98232000
,950
,350
,98390500
,925
,350
,98497000
,925
,325
,98620000
,900
,325
,98819500
,900
,300
,99092500
,875
,300
,99258000
,850
,300
Universitas Sumatera Utara
92
,99296000
,825
,300
,99354000
,825
,275
,99389000
,825
,250
,99397500
,800
,250
,99402500
,800
,225
,99461000
,775
,225
,99534500
,775
,200
,99560500
,750
,200
,99571000
,725
,200
,99579500
,700
,200
,99626500
,675
,200
,99676500
,650
,200
,99704000
,625
,200
,99736000
,600
,200
,99763000
,600
,175
,99780500
,600
,150
,99816000
,575
,150
,99851500
,575
,125
,99856500
,550
,125
,99867500
,525
,125
,99898500
,500
,125
,99925500
,475
,125
,99940000
,450
,125
,99949000
,400
,125
,99954000
,375
,125
,99966000
,375
,100
,99974500
,350
,100
,99978000
,325
,100
,99982500
,300
,100
,99985000
,275
,100
,99986500
,250
,100
,99988500
,250
,075
,99991500
,225
,075
,99993500
,225
,050
,99995000
,225
,025
,99997000
,200
,025
,99998500
,200
,000
1,00000000
,000
,000
Universitas Sumatera Utara
93
Lampiran 8
Data Hasil Penelitian
No
Nama
Umur
L/P
MR
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
Aman Sidabutar
Arifin Silitonga
Enda Malam
Johanis T
Sahat Sibarani
Netti
Paristono
Sehat Purba
Jamso Hutasoit
Sukiman
Syafiah
Erisa br Siahaan
Hedwar Sibarani
Katiman
Irianto
Jimmy Panjaitan
Joni Indra
Juandy
Marpaung
Kasume
Tambunan
M.Syahni
Tetap
Abd Thalib
Ahmad Kasrun
Andi Ramadani
Apul Sidabutar
Arifin
Aripin Bancin
52
52
40
45
63
47
58
40
52
48
53
58
49
70
61
36
43
33
L
L
P
L
L
P
L
L
L
L
L
P
L
L
L
L
L
L
53
41
52
57
52
23
61
41
43
19
20
21
22
23
24
25
26
27
Bil.
Total
1.2
0.65
2.11
4.71
13.32
9.83
2.53
5.43
32.49
7.31
0.98
0.62
5.13
2.25
4.66
2.66
14.96
0.73
AST
Albumin INR
Asites
HE
CP
586933
596253
593761
593411
544290
588439
589213
587426
544344
592770
590663
620072
559465
618126
410716
548819
621147
605427
Plt.(10
/L)
57
342
23
36
147
60
72
138
380
62
90
33
70
153
94
66
73
433
ø
VE
2
1
2
2
1
2
3
2
1
2
2
3
2
1
3
2
2
1
ALT
3
1
3
3
2
3
2
3
3
3
3
2
3
2
3
3
3
1
Etio.
SH
0
0
1
1
2
0
1
1
2
1
1
2
0
0
1
0
1
0
44
18
61
120
35
1075
200
367
93
166
41
18
88
35
142
47
526
15
2.4
3.1
1.6
1.6
2.8
2.9
2.9
3.1
2.6
2.1
2
2
2.1
2.9
2.7
1.9
3.8
4.5
1.58
0.99
1.75
1.58
1.5
1.39
1.24
1.5
1.21
1.74
1.48
1.19
2.09
0.9
2.11
1.72
1.63
1.47
2
1
3
3
1
2
2
3
2
1
2
2
2
2
2
2
2
1
0
0
1
0
0
0
0
0
0
0
0
0
0
0
0
2
0
0
L
600820
61
0.78
82
2.6
1.72
2
L
L
L
L
L
L
L
L
602903
606204
577673
555770
582156
5438?8
570102
620310
44
363
184
118
266
190
120
112
1.25
8.8
0.3
27.57
16.9
3.91
1.3
2.02
22
111
20
125
320
731
35
176
2.2
2.9
4.9
1.6
2
2
2
3.1
1.4
114
1.1
3.33
1.8
1.14
1.1
1.26
1
2
1
2
2
2
2
2
GGT
AIAG
9
16
38
61
34
106
54
55
77
127
31
15
49
29
100
27
66
15
Grup
ø
2
1
2
2
1
2
2
2
1
2
2
2
2
1
2
2
2
1
106
100
55
68
82
527
456
901
428
37
59
29
39
139
324
991
343
13
0.99948
0.80059
0.99986
0.99948
0.99847
0.99878
0.99552
0.99990
0.99383
0.99981
0.99856
0.98140
0.99999
0.80777
0.99999
0.99999
0.99932
0.97520
0
3
3
2
41
2
68
0.99974
0
0
0
0
0
0
0
0
2
3
1
3
3
3
2
2
0
1
0
0
0
1
1
1
3
1
1
3
1
2
1
2
16
38
16
141
136
236
23
49
2
1
1
2
1
2
1
2
8
179
18
31
358
663
15
492
0.99395
0.95992
0.68173
0.99999
0.99994
0.99785
0.93021
0.99405
Universitas Sumatera Utara
94
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
Armen
Sembiring
Asmara
Sitompul
Hotman
Baini
Bun Ngials
Darmadi
Hutagaol
Daud
Simarmata
Dedi Tarigan
Mariono
Lesmana
Misbah Udin
Nisma Siregar
Nurmansyah
Joni Purba
Rasyad Lubis
Kantin Barus
Koko Saputra
Krisna
Lisria
Sitanggang
Lidia Siahaan
Mestiana
sinurat
Roshidawati S
Rusli Sitepu
Salomo Sitepu
Sanimin
Selamat saragih
Sri Wondo
Wasina
53
L
548865
87
1.49
36
1.5
1.35
3
0
2
0
2
29
2
55
0.99686
72
L
617861
207
10.63
175
2.6
1.16
2
0
3
2
2
76
2
591
0.99722
67
51
54
43
L
L
L
L
468343
555380
623008
604612
426
65
121
108
0.1
0.68
2.17
11.26
15
29
33
175
3.5
2.7
1.7
2.1
1.25
1.1
1.04
1.92
0
1
2
1
0
0
0
0
1
2
3
2
1
0
1
1
1
1
1
2
11
37
19
55
1
1
1
2
39
53
34
86
0.95329
0.92287
0.94025
0.99996
53
L
618951
139
3.58
40
1.7
1.59
2
0
3
0
2
21
2
18
0.99950
46
44
L
L
585645
605782
75
135
20.34
0.43
100
12
1.6
2.7
2.17
0.96
3
1
0
0
3
1
1
0
3
1
38
8
2
1
66
13
0.99999
0.70096
42
55
38
43
65
49
48
40
51
L
P
L
L
L
P
L
L
P
611412
597747
602557
375897
609517
622248
627279
617442
614437
180
154
204
351
406
386
111
60
117
1.19
0.25
1.37
0.25
31.64
27.55
6.04
8.6
2.78
50
31
284
20
506
217
94
53
123
0.5
2.8
3.4
2.7
2.1
2.9
2.9
2.2
1,9
1.45
0.93
1.23
1.02
1.28
0.56
0.93
1.04
2.1
3
2
1
2
2
2
1
1
2
0
0
0
0
0
0
0
0
0
3
2
1
2
3
3
2
3
3
1
0
1
0
1
0
1
0
1
2
1
1
1
2
1
1
1
2
17
13
105
24
61
132
49
37
65
2
1
1
1
2
1
1
1
2
53
26
190
19
228
213
46
17
125
0.99919
0.70760
0.96267
0.79992
0.99667
0.12390
0.66239
0.86622
0.99999
72
41
P
P
594014
622241
674
73
0.38
0.9
47
76
3.1
2
1.02
1.26
2
1
0
2
2
3
0
1
1
2
25
49
1
2
24
60
0.87608
0.98537
48
58
49
64
72
54
55
P
L
L
L
L
P
P
622854
625504
614686
620531
624881
620866
625334
70
126
187
68
134
135
245
7.35
6.18
1.29
11.92
1.13
2.47
0.78
179
89
67
128
75
84
43
2.5
2.1
2.5
1.5
2.4
1.8
2.3
1.73
1.7
1
2.21
1.32
1.85
1.86
3
3
1
2
1
1
1
0
0
0
0
0
0
0
3
3
2
3
2
3
2
1
1
0
1
2
1
1
3
3
1
2
1
2
1
90
38
35
47
85
57
21
2
2
1
2
1
2
1
66
103
302
34
52
41
23
0.99975
0.99984
0.97720
0.99999
0.99517
0.99586
0.99993
Universitas Sumatera Utara
95
55
Aliaman
Tambunan
56 Ngatiah
57 Suhery
58 Mujiburrahman
59 Pandapotan
60 Wagini
61 M.saleh
62 Tuak Sembiring
63 Hj.Sawiyah
64 Z.Bukhari
65 Soden ginting
66 Parlindungan S
67 Wilson S
68 Maria
69 Janinuddin
70 Zunaidah
71 Toguan
72 Asni Narita
73 Hotmaida
74 Arifin Nasution
75 Arjuna Tarigan
76 Edi Susanto
77 Irsan Sihombing
78 Sofi Yusrizal
79 Nuzul Indra
80 Rohana
Keterangan :
62
L
628170
258
2.79
52
2.8
1.22
1
0
2
0
1
17
1
183
0.98703
57
44
35
36
88
57
58
78
59
70
46
57
64
44
49
45
50
42
52
57
45
62
36
33
48
P
L
L
L
P
L
L
P
L
L
L
L
P
L
P
L
P
P
L
L
L
L
P
L
P
547023
511721
515230
520074
618409
630138
512079
618020
608665
631722
632846
593013
600631
580992
615783
628699
538307
619717
597758
553344
564224
330684
595655
624720
620214
271
199
149
156
261
79
232
56
404
79
343
715
161
215
39
389
58
72
93
249
340
88
102
240
87
1.11
1.19
1.31
1.99
14.97
0.73
0.36
1.42
0.15
3.22
0.28
21.17
0.64
2,59
3.94
2.82
2.96
8.97
1.24
17.9
32.18
1.56
0.36
3.46
1.17
92
68
34
47
267
40
71
41
26
110
23
93
74
122
69
489
108
38
19
306
491
455
23
241
46
2.9
2.7
3.4
3
2.4
2.1
3.3
2.8
2.3
2.8
2.5
2
2.8
2.7
2
3.1
1.9
2.1
2.9
2.3
2.1
1.8
2.3
3.1
2.8
0.96
1.4
1.2
1.49
1.03
1.36
1.2
1.03
1.24
1.24
1.71
1.86
1.2
1.07
2.74
1.15
1.76
1.28
1.4
1.29
1.39
1.76
1.08
1.19
1.24
1
1
0
0
2
2
0
1
1
2
0
2
1
1
0
2
2
2
2
3
2
2
1
2
2
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
1
2
1
1
2
2
1
1
1
2
1
2
1
1
2
2
3
3
2
3
3
3
1
2
2
1
1
1
0
0
1
1
0
0
1
0
0
0
1
0
1
1
0
0
1
1
1
0
1
0
1
1
1
1
1
2
1
1
1
2
1
1
1
1
2
1
1
3
3
2
2
1
1
2
3
22
129
53
39
130
28
29
10
25
36
12
58
28
13
31
346
55
37
21
105
127
148
16
46
35
1
1
1
1
1
2
1
1
1
2
1
1
1
1
2
1
1
2
2
2
2
1
1
2
2
213
58
75
25
530
43
121
50
39
128
6
251
19
105
23
289
43
202
11
517
68
42
10
463
107
0.86784
0.99325
0.91909
0.99750
0.99400
0.99569
0.94805
0.98457
0.92891
0.98936
0.99958
0.99998
0.97224
0.90115
0.99999
0.96694
0.99987
0.99267
0.99249
0.99857
0.99573
0.99776
0.88076
0.98324
0.97786
Universitas Sumatera Utara
96
Keterangan:
*) Jenis Kelamin
Laki-laki
=1
Perempuan
=2
*) Asites
tidak ada Asites
Asites minimal
Asites sedang
Asites berat
*) Hepatic Encephalopathy (HE)
Tidak ada HE = 0
HE grade
=1
HE grade
=2
*) Etiologi SH
Bukan Hep. B&C
Hepatitis B
Hepatitis C
Hepatitis B&C
=0
=1
=2
=3
=0
=1
=2
=3
*) Child Pugh
A (Ringan)= 1
B(Sedang)= 2
C(Berat) = 3
*) Varises Esofagus
F1
=1
F2
=2
F3
=3
*) Diameter Grup
Kecil = 1
Besar = 2
Universitas Sumatera Utara
Lampiran 1 : Surat Persetujuan Komite Etik
Universitas Sumatera Utara
58
Lampiran 2
LEMBAR PENJELASAN KEPADA CALON SUBJEK PENELITIAN
Selamat pagi/ siang Bapak/ Ibu, pada hari ini saya, dr. Dedy Mhd,Abu
Bakar, peserta Pendidikan Pasca Sarjana Ilmu Penyakit Dalam/ Magister
Klinik FK-USU Medan akan melakukan penelitian yang berjudul ”Hubungan
Besar Varises Esofagus Secara Endoskopi dengan AIAG score pada Penderita
Sirosis Hati”.
Kepada Bapak/ Ibu yang bersedia mengikuti penelitian ini nantinya
akan diminta mengisi surat persetujuan ikut dalam penelitian, mengikuti
wawancara untuk mencari adanya hal-hal yang dapat mengganggu penelitian,
dan dilakukan pemeriksaan laboratorium berupa pemeriksaan darah sebanyak
15 cc (1 sendok makan) yang akan diambil dari lengan oleh ahli untuk menilai
sebuah skor yang disebut AIAG Score melalui parameter umur, INR, γGT, dan
albumin. Kemudian hasil skor tersebut akan saya bandingkan dengan hasil
pemeriksaan endoskopi.
Manfaat penelitian ini adalah dapat memberikan informasi tentang
adanya varises esofagus pada penderita sirosis hati serta meringankan biaya
pemeriksaan untuk pemantauan varises esofagus dan pemeriksaan menjadi
lebih sederhana, murah dan tidak membutuhkan waktu yang lama. Pada
penelitian ini tidak menimbulkan efek samping apapun, hanya risiko yang
dapat terjadi dari penelitian ini adalah terjadinya lebam setelah pengambilan
darah.
Setelah hasil akhir diperoleh, nantinya akan terlihat apakah terdapat
hubungan antara besar varises esofagus secara endoskopi dengan AIAG score.
Bila masih terdapat pertanyaan atau keluhan sewaktu penelitian ini berjalan,
maka Bapak/Ibu dapat menghubungi saya pada:
Nama
: dr. Dedy Mhd. Abu Bakar
Alamat
: Jl. Jl. Ekarasmi, gg. Ekarasmi I no. 15, Kec. Medan Johor, Medan
Telepon : 085350398750
Peneliti,
(dr. Dedy Mhd. Abu Bakar)
Universitas Sumatera Utara
59
Lampiran 3
SURAT PERSETUJUAN SETELAH PENJELASAN
(INFORMED CONSENT )
Saya yang bertanda tangan dibawah ini :
Nama
:...........................................................................................
Alamat
:...........................................................................................
Umur
:........................ Tahun
Jenis Kelamin : Laki-laki/ Perempuan*
No Telp/ HP
:
Setelah mendapat penjelasan dari peneliti tentang kebaikan dan keburukan
prosedur penelitian ini, menyatakan BERSEDIA ikut serta dalam penelitian
tentang ”Hubungan AIAG score dengan Besar Varises Esofagus Secara Endoskopi
pada Penderita Sirosis Hati”. Apabila sewaktu-waktu saya mengundurkan diri dari
penelitian ini, kepada saya tidak dituntut apapun.
Demikianlah surat persetujuan bersedia ikut dalam penelitian ini saya buat,
untuk dapat digunakan seperlunya.
Medan, ...........................2014
Yang memberi pernyataan,
(.............................................)
*Coret yang tidak perlu
Universitas Sumatera Utara
60
Lampiran 4
DATA PESERTA
Tanggal:
MR
:
No. Peserta
:
I. IDENTITAS PRIBADI
Nama
:
Tempat/ Tanggal lahir :
Jenis kelamin
: Laki-laki / Perempuan
Pendidikan terakhir
:
Pekerjaan
:
Status
: Kawin / Belum Kawin.
Faktor risiko
:
No. Telp/Hp
:
II. PEMERIKSAAN FISIK
III. PEMERIKSAAN LABORATORIUM
Parameter
Nilai
INR
γGT (U/L)
Albumin (g/dL)
Universitas Sumatera Utara
61
Lampiran 5
LEMBAR KUESIONER KEPATUHAN PENGOBATAN MORISKY-8
Nilai
No
Pertanyaan
Ya/ Tidak
(Ya=0,
Tidak=1)
1
Apakah anda terkadang lupa mengkonsumsi
obat ?
Pasien terkadang tidak mengkonsumsi obat
2
selain alasan lupa. Dalam 2 minggu terakhir,
apakah ada hari dimana anda tidak
mengkonsumsi obat ?
Pernahkah anda mengurangi atau menghenti-
3
kan obat tanpa sepengetahuan dokter karena
anda
merasa
tidak
nyaman
saat
mengkonsumsinya ?
4
5
6
Saat anda bepergian atau keluar rumah, apakah
anda kadang lupa mengkonsumsi obat ?
Apakah
anda
mengkonsumsi
obat
anda
semalam ?*
Saat anda merasa gejala anda sudah berkurang,
apakah anda berhenti mengkonsumsi obat ?
Mengkonsumsi obat setiap hari merupakan
7
ketidaknyamanan bagi beberapa orang. Apakah
anda merasa jenuh dengan pengobatan anda ?
Seberapa
8
sering
anda
kesulitan
untuk
mengingat mengkonsumsi obat anda ?
A. Tidak pernah/ Jarang
Universitas Sumatera Utara
62
B. Sekali-sekali
C. Kadang-kadang
D. Sering
E. Setiap saat
A= 1; B-E= 0
TOTAL NILAI
* Untuk no.5 bila jawaban Ya= 1, Tidak= 0
Universitas Sumatera Utara
63
Lampiran 6
DAFTAR RIWAYAT HIDUP
I.
Identitas Pribadi
Nama
: dr. Dedy Muhammad Abu Bakar
Tempat/Tgl Lahir : Padangsidimpuan/ 28 Februari 1979
Suku/Bangsa
: Mandailing / Indonesia
Agama
: Islam
Alamat
: Jl. Ekarasmi, gg.Ekarasmi I no.15, Kec. Medan
Johor, Medan
II.
Pendidikan
SD Negeri 15 Padangsidimpuan
Tamat Tahun 1992
SMP Negeri 1 Padangsidimpuan
Tamat Tahun 1995
SMU Negeri 1 Padangsidimpuan
Tamat Tahun 1998
FK Universitas Syiah Kuala
Tamat Tahun 2006
III.
Riwayat Pekerjaan
PNS RSUD Panyabungan tahun 2009-sekarang
IV.
Perkumpulan Profesi
IDI Cabang Panyabungan
PAPDI Sumatera Utara
V.
Journal Reading
1. Takikawa Y, Ryujin Endo, Suzuki K, Tsubouchi H. Early
prediction of short-term development of hepatic encephalopathy in
patient with acute liver disease unrelated to paracetamol. A
prospective study in Japan. Journal of Hepatology. 2009;58:1021–
1029.
2. Mahesh Kumar Goenka, Majumder S, Pradeepta Kumar Sethy,
Chakraborty M. Helicobacter pylori, negative-steroidal anti-
Universitas Sumatera Utara
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inflamatory drug-negative peptic ulcer in India. Indian J
Gastroenterol. 2011;30(1):33-37.
3. Sergio A.Gonzales, Forcada P, Inserra F, Obregon S, Olano D.
Sodium intake is associated with parasympathetic tone and
metabolic parameters in mild hypertension. American Journal of
Hypertension. 2012;25(1):620-624.
4. Ch. Venkata Rama Krishna, P.V.L.N. Srinivasa Rao, V. Siva
Kumar. Acute renal failure in falciparum malaria: Clinical
characteristics, demonstration of oxidative stress, and
prognostication. Saudi J Kidney Dis Transpl. 2012:23(2):296-300.
5. Perluigi Tricoci, M.D., Ph.D., Zhen Huang, M.S., Claes Held,
M.D., Ph.D., et.al. Thrombin-receptor antsgonist vorapaxar in acute
coronary syndromes. N Engl J Med. 2012;366:20-23.
6. Byron s. Kennedy, M.D., Ph.D., M.P.H., Brenden Bedard, M.P.H.,
Mary Younge R.N., et.al. Outbreak of mycobacterium chelonae in
infection associated with tatto ink. N Engl J Med. 2012;367:10201024.
7. Siti Nurleila, Din Syafruddin, Iqbal R.F. Elyazar, Baird K. Serious
and fatal illlness associated with falciparum amd vivax malaria
among patient admitted to hospital at West Sumba in Eastern
Indonesia. Am J Trop Med Hyg. 2012;87(1):41-49.
8. Mehmet Gunduz, Ercan Gundus, Kircelli F, okur N, Ozkaya M.
Role of surrogate of atherosclerosis in clinical and subclinical
thyroidism. International Journal of Endocrinology. 2012.
9. Catherine Pihiker, M.D., Barbara Linder, MD, Ph.D., Dana
dabelea, M.D., Ph.D., et.al. Insulin regimens and clinical outcome
in a type 1 diabetes cohort. Diabetes care. 2012;36:27-33.
10. Ilhami Berber, halit Diri, Mehmet Ali Erkurt, et.al. Evaluation of
ferric and ferrous iron therapies in womwn with iron deficiency
anaemia. Hindawi Advance in Hematology. 2014.
11. Thomas F. Imperiale, M.D., David F. Ranso hoff, M.D., Steven H.
Itzkowits, M.D., et.al. Multitarget stool DNA testing for colorectalcancer screening. N Engl J Med. 2014;370:1287-1297.
12. Ryo Oda, Fujiwara H, Tokunaga D, Nakamura S, et.al. How do
anti_TNF therapies affect gait finction in patients with rheumatoid
arthritis International journal of Reumatic Diseases, 2014;17:57-62.
13. Takashi Abe, Ph.D, Jeremy P. Loenneke, Ph.D, Tetsuo Fukunaga,
Ph.D. Interrelationship between bosymass to waist circumference
ratio, body mass inde, and total body muscularity in older women.
Journal of Clinical Gerontology. 2014;58-64.
Universitas Sumatera Utara
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14. Chih-hsin Lee, Ming-Chia Lee, Hsien-Ho Lin, et.al. Pulmonary
Tuberculosis and delay in anti-tuberculous treatment are important
risk factors for chronic obstructive pulmonary disease. Plos ONE
2012;7(5).
15. Abdussalam M Alaithan, Javed I Memon, Rifat S Rehmani, et.al.
Chronic obstructive pulmonary disease: hospital and intensive care
unit in kingdom of Saudi Arabia. International Journal of COPD.
2012;7:819-823.
16. K. Kontogianni, P. Bakakos, G. Hillas, et.al. Level of prostaglandin
E-2 and cysteinyl-leukotrienes in sputum supernatant of patients
with asthma: the effect of smoking. Clinical & Experimental
Allergy. 2012;43:616-624.
17. R.Soundravally, S.L. Hoti, Shripad A. Patil, et.al. Association
between proinflamatory cytokines and lipid peroxidation in patients
with severe dengue disease around defervescence. Intenational
Journal of Infectious disease.2014;18:68-72.
VI.
Tulisan Ilmiah di Departemen Ilmu Penyakit Dalam
1. Thrombotic Thrombocypenic Purpura dan Hemolitic Uremic
Syndrome
2. Gangguan Somatisasi
3. Gangguan hati padan HIV
4. Nocturnal Hemodialysis
5. Hipertiroidisme pada mola hidatidosa
6. Cardiomyopathy
7. Tumor Mediastinum
VII.
1.
2.
Publikasi Ilmiah
Abu Bakar DM., Realsyah T, Safri Z, Hasan R. Endokarditis
Infektif: Laporan kasus. Kongres Nasional XV Perhimpunan
Dokter Spesialis Penyakit Dalam Indonesia, KOPAPDI XV,
Medan, 2012.
Abu Bakar DM, Ginting F, Ginting Y. Hubungan perubahan kadar
hemoglobin dengan kadar CD4 pada pasien HIV yang diterapi
dengan ARV selama 6 bulan: KONAS PETRI XIX & PKWI XVI,
Makassar, 2013
Universitas Sumatera Utara
66
VIII.
Partisipasi Dalam Kegiatan Ilmiah
1. Peserta Kursus “General Life Support”: RSUP.HAM. Medan, Mei
2009.
2. Peserta Simposium “Respiratory Evidenced and Respiratory
Competence Synergy on Clinical Practice”. MERCY 2010. Medan,
19-21 Maret 2010.
3. Peserta Simposium “Current Management in Internal Medicine”.
11th Annual Scientific Meeting Internal Medicine. Medan, 1-3 April
2010.
4. Peserta Simposium “Update on Diabetes Management and Medical
Nutrition Therapy”. PAPDI. Medan, 17 April 2010.
5. Peserta Simposium “Pemenuhan Gizi Seimbang dengan Susu UHT”.
IDI. Medan, 31 Juli 2010.
6. Peserta Simposium “Recent Advances on Management of Secondary
Ischemic Stroke Prevention”. PERDOSSI. Medan, 27 November
2010.
7. Peserta Kursus “Advanced Electrocardiography (ECG)”. PERKI.
Medan 10-11 Desember 2010.
8. Peserta Workshop “Medical Skill Upgrade Cardio-Metabolic”.
PAPDI. Medan 2 April 2011.
9. Peserta Simposium “Clinical Rheumatology in Daily Practice”.
Rheumatology Update 2011. Medan, 9-10 Juli 2011.
10. Peserta Simposium “Patophysiology and Recent Management of
Chronic Constipation and Acute Diarrhea”. The Indonesian Society
of Gastroenterology. Medan, 13 November 2011.
11. Peserta Simposium “The New Option of Insulin Resistance
Treatment in Type 2 Diabetes”. PERKENI. Medan, 20 November
2011.
12. Peserta Free Paper Poster Presentation “Kongres Nasional XV
Perhimpunan Dokter Spesialis Penyakit Dalam Indonesia
(KOPAPDI XV)”, Medan, 12-15 Desember 2012.
13. Peserta Workshop “Diabetes Update for Excellent”. PERKENI.
Medan, 17 Maret 2012.
14. Peserta Simposium “A New Novel DPP-4 Inhibitor for T2DM
Treatment”. PERKENI. Medan, 1 April 2012.
15. Peserta Simposium “Diabetic Neuropathy”. PERKENI. Medan, 8
September 2012.
16. Peserta Workshop “Terapi Insulin”. Dies Natalis 60 FK-USU.
Medan, 11 September 2012.
17. Peserta Simposium “Right from The Start: An Urgent Concern”.
FEDS-5. Medan, 23 Februari 2013.
18. Peserta Workshop “Managing Diabetes Mellitus: From A to Z”.
Jeanne Latu Conference, 2 Maret 2013.
Universitas Sumatera Utara
67
19. Peserta Simposium “Recent Management in Helicobacter pylori
Infection, Irritable Bowel Syndrome and Hepatic Encephalopathy”.
PPHI. Medan, 20 April 2013.
20. Peserta Pelatihan Program Pengembangan Pendidikan Keprofesian
Berkelanjutan Ultrasonografi Tahap Satu bagi Spesialis dan PPDS
Penyakit Dalam. Departemen Penyakit Dalam FK USU dan PUSKI.
Medan, 15-18 April 2013.
21. Peserta Simposium “Current and Future Treatment in Diabetes
Management”. PERKENI. Medan, 11 Mei 2013.
22. Peserta Kursus “Diabetes Camp 2013”. PERSADIA. Berastagi, 1819 Mei 2013.
23. Peserta Kursus “Partnership for Diabetes Control in Indonesia”.
PERKENI. Medan, 7-9 Juni 2013.
24. Peserta Simposium “Linagliptin: A Novel Unique DPP IV Inhibitor”.
PAPDI. Medan, 11 Juni 2013.
Universitas Sumatera Utara
68
Lampiran 7
HASIL STATISTIK
Frequency Table
Jk
Frequency
Valid
Percent
Valid Percent
Cumulative Percent
laki-laki
60
75,0
75,0
75,0
perempuan
20
25,0
25,0
100,0
Total
80
100,0
100,0
Asites
Frequency
Percent
6
7,5
7,5
7,5
Minimal
25
31,3
31,3
38,8
Sedang
40
50,0
50,0
88,8
Berat
9
11,3
11,3
100,0
Total
80
100,0
100,0
Valid tidak ada
Valid Percent
Cumulative Percent
HE
Frequency Percent
Valid
Tidak ada
Valid Percent Cumulative Percent
77
96,3
96,3
96,3
HE grade 1
1
1,3
1,3
97,5
HE grade 2
2
2,5
2,5
100,0
80
100,0
100,0
Total
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CP
Frequency Percent Valid Percent Cumulative Percent
Valid
A (ringan)
16
20,0
20,0
20,0
B (sedang)
28
35,0
35,0
55,0
C (berat)
36
45,0
45,0
100,0
Total
80
100,0
100,0
EtioSH
Frequency Percent
Valid
Valid Percent
Cumulative Percent
Bukan Hep B dan C
34
42,5
42,5
42,5
Hepatitis B
40
50,0
50,0
92,5
Hepatitis C
5
6,3
6,3
98,8
Hep. B dan C
1
1,3
1,3
100,0
Total
80
100,0
100,0
Diameter VE
Frequency Percent
Valid
Valid Percent
Cumulative Percent
F1
40
50,0
50,0
50,0
F2
29
36,3
36,3
86,3
F3
11
13,8
13,8
100,0
Total
80
100,0
100,0
Ukuran Varises Esofagus
requency
Valid
Percent
Valid Percent
Cumulative Percent
Kecil
40
50,0
50,0
50,0
Besar
40
50,0
50,0
100,0
Total
80
100,0
100,0
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Case Processing Summary
Cases
Valid
umur
Missing
Total
N
Percent
N
Percent
N
Percent
80
100,0%
0
0,0%
80
100,0%
Descriptives
Statistic
umur
Mean
51,55
95% Confidence Interval
Lower Bound
49,05
for Mean
Upper Bound
54,05
5% Trimmed Mean
51,25
Median
51,50
Variance
126,504
Std. Deviation
11,247
Minimum
23
Maximum
88
Range
65
Interquartile Range
15
Std. Error
1,257
Skewness
,488
,269
Kurtosis
,768
,532
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Crosstabs
Case Processing Summary
Cases
Valid
N
Percent
Missing
N
Total
Percent
N
Percent
jk * Ukuran Varises Esofagus
80
100,0%
0
0,0%
80
100,0%
Asites * Ukuran Varises Esofagus
80
100,0%
0
0,0%
80
100,0%
HE * Ukuran Varises Esofagus
80
100,0%
0
0,0%
80
100,0%
CP * Ukuran Varises Esofagus
80
100,0%
0
0,0%
80
100,0%
EtioSH * Ukuran Varises Esofagus
80
100,0%
0
0,0%
80
100,0%
jk * Ukuran Varises Esofagus
Crosstab
Ukuran Varises Esofagus
Kecil
laki-laki
Count
Expected Count
% within jk
% within Ukuran Varises
Esofagus
perempuan
Count
Expected Count
% within jk
% within Ukuran Varises
Esofagus
Total
Count
Expected Count
% within jk
% within Ukuran Varises
Esofagus
Besar
Total
30
30
60
30,0
30,0
60,0
50,0%
50,0%
100,0%
75,0%
75,0%
75,0%
10
10
20
10,0
10,0
20,0
50,0%
50,0%
100,0%
25,0%
25,0%
25,0%
40
40
80
40,0
40,0
80,0
50,0%
50,0%
100,0%
100,0%
100,0%
100,0%
Universitas Sumatera Utara
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Chi-Square Tests
Asymp. Sig.
Value
Pearson Chi-Square
Continuity Correction
df
Likelihood Ratio
.
1
1,000
,000
1
1,000
,000
1
1,000
,000
b
(2-sided)
a
Fisher's Exact Test
Exact Sig
Exact Sig.
(2-sided)
(1-sided)
1,000
Linear-by-Linear Association
,000
N of Valid Cases
1
,602
1,000
80
a. 0 cells (0,0%) have expected count less than 5. The minimum expected count is 10,00.
Computed only for a 2x2 table
Risk Estimate
95% Confidence Interval
Value
Odds Ratio for jk (laki-laki /
perempuan)
For cohort Ukuran Varises
Esofagus = Kecil
For cohort Ukuran Varises
Esofagus = Besar
N of Valid Cases
Lower
Upper
1,000
,363
2,751
1,000
,603
1,659
1,000
,603
1,659
80
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Asites * Ukuran Varises Esofagus
Crosstab
Ukuran Varises Esofagus
Kecil
Asites
tidak ada
Count
1
6
Expected Count
3,0
3,0
6,0
% within Asites
83,3%
16,7%
100,0%
12,5%
2,5%
7,5%
20
5
25
Expected Count
12,5
12,5
25,0
% within Asites
80,0%
20,0%
100,0%
50,0%
12,5%
31,3%
15
25
40
Expected Count
20,0
20,0
40,0
% within Asites
37,5%
62,5%
100,0%
37,5%
62,5%
50,0%
0
9
9
Expected Count
4,5
4,5
9,0
% within Asites
0,0%
100,0%
100,0%
0,0%
22,5%
11,3%
40
40
80
Expected Count
40,0
40,0
80,0
% within Asites
50,0%
50,0%
100,0%
100,0%
100,0%
100,0%
Esofagus
Count
% within Ukuran Varises
Esofagus
sedang
Count
% within Ukuran Varises
Esofagus
berat
Count
% within Ukuran Varises
Esofagus
Total
Total
5
% within Ukuran Varises
minimal
Besar
Count
% within Ukuran Varises
Esofagus
Universitas Sumatera Utara
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Chi-Square Tests
Asymp. Sig. (2Value
df
sided)
a
3
,000
Likelihood Ratio
27,552
3
,000
Linear-by-Linear Association
20,979
1
,000
Pearson Chi-Square
23,167
N of Valid Cases
80
a. 4 cells (50,0%) have expected count less than 5. The minimum
expected count is 3,00.
Risk Estimate
Value
Odds Ratio for Asites (tidak
a
ada / minimal)
a. Risk Estimate statistics cannot be computed. They
are only computed for a 2*2 table without empty cells.
HE * Ukuran Varises Esofagus
Crosstab
Ukuran Varises Esofagus
Kecil
HE
Tidak ada
Count
Total
40
37
77
38,5
38,5
77,0
51,9%
48,1%
100,0%
100,0%
92,5%
96,3%
Count
0
1
1
Expected Count
,5
,5
1,0
0,0%
100,0%
100,0%
0,0%
2,5%
1,3%
Expected Count
% within HE
% within Ukuran Varises
Esofagus
HE grade 1
Besar
% within HE
% within Ukuran Varises
Esofagus
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E grade 2
Count
Expected Count
% within HE
% within Ukuran Varises
Esofagus
Total
Count
Expected Count
% within HE
% within Ukuran Varises
Esofagus
0
2
2
1,0
1,0
2,0
0,0%
100,0%
100,0%
0,0%
5,0%
2,5%
40
40
80
40,0
40,0
80,0
50,0%
50,0%
100,0%
100,0%
100,0%
100,0%
Chi-Square Tests
A symp. Sig
Value
df
(2-sided)
a
2
,210
Likelihood Ratio
4,276
2
,118
Linear-by-Linear Association
2,842
1
,092
Pearson Chi-Square
N of Valid Cases
3,117
80
a. 4 cells (66,7%) have expected count less than 5. The minimum
expected count is ,50.
Risk Estimate
Value
Odds Ratio for HE (Tidak
a
ada / HE grade 1)
a. Risk Estimate statistics cannot be computed.
They are only computed for a 2*2 table without empty
cells.
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76
CP * Ukuran Varises Esofagus
Crosstab
Ukuran Varises Esofagus
Kecil
CP
A (ringan)
16
0
16
Expected Count
8,0
8,0
16,0
100,0%
0,0%
100,0%
40,0%
0,0%
20,0%
16
12
28
14,0
14,0
28,0
57,1%
42,9%
100,0%
40,0%
30,0%
35,0%
8
28
36
18,0
18,0
36,0
22,2%
77,8%
100,0%
20,0%
70,0%
45,0%
40
40
80
40,0
40,0
80,0
50,0%
50,0%
100,0%
100,0%
100,0%
100,0%
% within Ukuran Varises
Esofagus
Count
Expected Count
% within CP
% within Ukuran Varises
Esofagus
C (berat)
Count
Expected Count
% within CP
% within Ukuran Varises
Esofagus
Total
Total
Count
% within CP
B (sedang)
Besar
Count
Expected Count
% within CP
% within Ukuran Varises
Esofagus
Chi-Square Tests
Asymp. Sig.
Value
df
(2-sided)
a
2
,000
Likelihood Ratio
34,522
2
,000
Linear-by-Linear Association
27,230
1
,000
Pearson Chi-Square
N of Valid Cases
27,683
80
0 cells (0,0%) have expected count less than 5. The minimum expected
count is 8,00.
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Risk Estimate
Value
Odds Ratio for CP (A (ringan) / B
a
(sedang))
a Risk Estimate statistics cannot be computed. They are
only computed for a 2*2 table without empty cells.
EtioSH * Ukuran Varises Esofagus
Crosstab
Ukuran Varises Esofagus
Kecil
EtioSH
Bukan Hep B dan C
Hepatitis B
Hepatitis C
Hep. B dan C
Total
Count
Besar
Total
22
12
34
Expected Count
17,0
17,0
34,0
% within EtioSH
64,7%
35,3%
100,0%
% within Ukuran Varises Esofagus
55,0%
30,0%
42,5%
15
25
40
Expected Count
20,0
20,0
40,0
% within EtioSH
37,5%
62,5%
100,0%
% within Ukuran Varises Esofagus
37,5%
62,5%
50,0%
3
2
5
Expected Count
2,5
2,5
5,0
% within EtioSH
60,0%
40,0%
100,0%
% within Ukuran Varises Esofagus
7,5%
5,0%
6,3%
Count
0
1
1
Expected Count
,5
,5
1,0
% within EtioSH
0,0%
100,0%
100,0%
% within Ukuran Varises Esofagus
0,0%
2,5%
1,3%
40
40
80
Expected Count
40,0
40,0
80,0
% within EtioSH
50,0%
50,0%
100,0%
% within Ukuran Varises Esofagus
100,0%
100,0%
100,0%
Count
Count
Count
Universitas Sumatera Utara
78
Chi-Square Tests
Asymp. Sig. (2Value
df
sided)
a
3
,084
Likelihood Ratio
7,099
3
,069
Linear-by-Linear Association
3,526
1
,060
Pearson Chi-Square
6,641
N of Valid Cases
80
4 cells (50,0%) have expected count less than 5. The minimum expected
count is ,50.
Risk Estimate
Value
Odds Ratio for EtioSH (Bukan Hep
a
B dan C / Hepatitis B)
Risk Estimate statistics cannot be computed.
They are only computed for a 2*2 table without
empty cells.
Case Processing Summary
Cases
Ukuran Varises Esofagus
Valid
N
umur
Missing
Percent
N
Total
Percent
N
Percent
Kecil
40
100,0%
0
0,0%
40
100,0%
Besar
40
100,0%
0
0,0%
40
100,0%
Descriptives
Ukuran Varises Esofagus
umur
Kecil
Statistic
Mean
52,53
95% Confidence Interval for
Lower Bound
48,30
Mean
Upper Bound
56,75
5% Trimmed Mean
52,19
Median
52,00
td. Error
2,091
Universitas Sumatera Utara
79
Variance
174,820
Std. Deviation
13,222
Minimum
23
Maximum
88
Range
65
Interquartile Range
17
Besar
Skewness
,369
,374
Kurtosis
,419
,733
Mean
50,58
1,410
95% Confidence Interval
Lower Bound
47,72
for Mean
Upper Bound
53,43
5% Trimmed Mean
50,33
Median
50,00
Variance
79,481
Std. Deviation
8,915
Minimum
33
Maximum
72
Range
39
Interquartile Range
14
Skewness
,417
,374
Kurtosis
-,068
,733
Tests of Normality
Kolmogorov-Smirnov
Ukuran Varises Esofagus
umur
Kecil
Besar
Statistic
,068
,093
df
40
40
a
Shapiro-Wilk
Sig.
Statistic Df
Sig.
,200
*
,988
40
,945
,200
*
,978
40
,630
*. This is a lower bound of the true significance.
a. Lilliefors Significance Correction
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80
T-Test
Group Statistics
Ukuran Varises Esofagus
umur
N
Mean
Std. Deviation
Std. Error Mean
Kecil
40
52,53
13,222
2,091
Besar
40
50,58
8,915
1,410
Independent Samples Test
evene's Test
for Equality of
Variances
t-test for Equality of Means
95% Confidence
Mean
Differen
ce
F
umur Equal variances
assumed
4,055
Sig.
,047
Equal variances
not assumed
t
Df
Std. Error
Interval of the
Difference
Difference
Sig. (2-tailed)
Lower
Upper
,773
78
,442
1,950
2,521
-3,070
6,970
,773
68,388
,442
1,950
2,521
-3,081
6,981
Case Processing Summary
Cases
Ukuran
Valid
Varises Esofagus
N
PLT, ribu/ul
Billirubin Total, mg/dl
AST, unit/L
Albumin, g/L
INR
Missing
Percent
N
Total
Percent
N
Percent
Kecil
40
100,0%
0
0,0%
40
100,0%
Besar
40
100,0%
0
0,0%
40
100,0%
Kecil
40
100,0%
0
0,0%
40
100,0%
Besar
40
100,0%
0
0,0%
40
100,0%
Kecil
40
100,0%
0
0,0%
40
100,0%
Besar
40
100,0%
0
0,0%
40
100,0%
Kecil
40
100,0%
0
0,0%
40
100,0%
Besar
40
100,0%
0
0,0%
40
100,0%
Kecil
40
100,0%
0
0,0%
40
100,0%
Universitas Sumatera Utara
81
ALT, mg/dl
Gamma GT, UI/L
AIAG Score
Besar
40
100,0%
0
0,0%
40
100,0%
Kecil
40
100,0%
0
0,0%
40
100,0%
Besar
40
100,0%
0
0,0%
40
100,0%
Kecil
40
100,0%
0
0,0%
40
100,0%
Besar
40
100,0%
0
0,0%
40
100,0%
Kecil
40
100,0%
0
0,0%
40
100,0%
Besar
40
100,0%
0
0,0%
40
100,0%
Descriptives
Ukuran Varises Esofagus
PLT, ribu/ul
Kecil
Statistic
Mean
242,45
95 % Confidence Interval for
Lower Bound
193,31
Mean
Upper Bound
291,59
5% Trimmed Mean
227,64
Median
201,50
Variance
24,297
23613,023
Std. Deviation
Besar
Std. Error
153,665
Minimum
56
Maximum
715
Range
659
Interquartile Range
215
Skewness
1,286
,374
Kurtosis
1,922
,733
Mean
111,70
12,811
95% Confidence Interval for Lower Bound
Mean
Upper Bound
85,79
137,61
5% Trimmed Mean
101,83
Median
83,00
Variance
Std. Deviation
6564,574
81,022
Minimum
23
Maximum
406
Range
383
Interquartile Range
66
Universitas Sumatera Utara
82
Billirubin Total, mg/dl
Kecil
Besar
AST, unit/L
Kecil
Skewness
2,040
,374
Kurtosis
4,547
,733
Mean
5,1420
1,30211
95% Confidence Interval for
Lower Bound
2,5082
Mean
Upper Bound
7,7758
5% Trimmed Mean
4,0386
Median
1,3050
Variance
67,820
Std. Deviation
8,23529
Minimum
,10
Maximum
32,49
Range
32,39
Interquartile Range
4,79
Skewness
2,032
,374
Kurtosis
3,331
,733
Mean
7,0550
1,31137
95% Confidence Interval for
Lower Bound
4,4025
Mean
Upper Bound
9,7075
5% Trimmed Mean
6,0286
Median
3,7450
Variance
68,788
Std. Deviation
8,29383
Minimum
,62
Maximum
32,18
Range
31,56
Interquartile Range
8,31
Skewness
1,916
,374
Kurtosis
3,132
,733
Mean
94,68
18,124
95% Confidence Interval for Lower Bound
Mean
Upper Bound
58,02
131,33
5% Trimmed Mean
78,22
Median
49,50
Variance
Std. Deviation
13138,533
114,623
Minimum
12
Maximum
489
Universitas Sumatera Utara
83
Besar
Range
477
Interquartile Range
64
Skewness
2,276
,374
Kurtosis
4,800
,733
Mean
178,80
34,234
95% Confidence Interval for
Lower Bound
109,55
Mean
Upper Bound
248,05
5% Trimmed Mean
147,47
Median
105,00
Variance
46879,138
Std. Deviation
Albumin, g/L
Kecil
Besar
216,516
Minimum
18
Maximum
1075
Range
1057
Interquartile Range
132
Skewness
2,555
,374
Kurtosis
7,383
,733
Mean
2,755
,1003
95% Confidence Interval for
Lower Bound
2,552
Mean
Upper Bound
2,958
5% Trimmed Mean
2,703
Median
2,750
Variance
,402
Std. Deviation
,6341
Minimum
1,7
Maximum
4,9
Range
3,2
Interquartile Range
,7
Skewness
1,261
,374
Kurtosis
3,245
,733
Mean
2,218
,0949
95% Confidence Interval for Lower Bound
Mean
Upper Bound
2,025
2,410
5% Trimmed Mean
2,217
Median
2,100
Variance
,360
Std. Deviation
,6004
Universitas Sumatera Utara
84
INR
Kecil
Minimum
,5
Maximum
3,8
Range
3,3
Interquartile Range
,8
Skewness
,067
,374
Kurtosis
1,134
,733
Mean
1,4233
,19979
95% Confidence Interval for Lower Bound
Mean
Upper Bound
1,2383
Median
1,1750
Variance
1,597
1,26357
Minimum
,56
Maximum
9,00
Range
8,44
Interquartile Range
,42
Skewness
5,798
,374
Kurtosis
35,435
,733
Mean
1,6188
,07156
95% Confidence Interval for Lower Bound
Mean
Upper Bound
1,7635
1,5661
Median
1,4900
,205
Std. Deviation
Kecil
1,4740
5% Trimmed Mean
Variance
ALT, mg/dl
1,8274
5% Trimmed Mean
Std. Deviation
Besar
1,0191
,45256
Minimum
1,14
Maximum
3,33
Range
2,19
Interquartile Range
,47
Skewness
1,850
,374
Kurtosis
4,499
,733
Mean
52,88
9,847
95% Confidence Interval for Lower Bound
Mean
Upper Bound
32,96
72,79
5% Trimmed Mean
44,53
Median
29,00
Universitas Sumatera Utara
85
Variance
3878,676
Std. Deviation
Besar
62,279
Minimum
8
Maximum
346
Range
338
Interquartile Range
41
Skewness
3,045
,374
Kurtosis
11,992
,733
Mean
58,25
6,884
95% Confidence Interval for
Lower Bound
44,33
Mean
Upper Bound
72,17
5% Trimmed Mean
53,58
Median
48,00
Variance
1895,577
Std. Deviation
Gamma GT, UI/L
Kecil
43,538
Minimum
9
Maximum
236
Range
227
Interquartile Range
35
Skewness
2,130
,374
Kurtosis
6,146
,733
Mean
111,05
19,970
95% Confidence Interval for Lower Bound
Mean
Upper Bound
151,44
5% Trimmed Mean
96,33
Median
51,00
Variance
15952,254
Std. Deviation
Besar
70,66
126,302
Minimum
6
Maximum
530
Range
524
Interquartile Range
159
Skewness
1,679
,374
Kurtosis
2,496
,733
Mean
207,13
40,137
95% Confidence Interval for Lower Bound
Mean
Upper Bound
125,94
288,31
Universitas Sumatera Utara
86
5% Trimmed Mean
177,06
Median
68,00
Variance
Std. Deviation
AIAG Score
Kecil
253,849
Minimum
8
Maximum
991
Range
983
Interquartile Range
297
Skewness
1,631
,374
Kurtosis
1,982
,733
Mean
,89936575 ,025083833
95% Confidence Interval for
Lower Bound ,84862891
Mean
Upper Bound ,95010259
5% Trimmed Mean
,92190056
Median
,95660500
Variance
Std. Deviation
Besar
64439,497
,025
,158644087
Minimum
,123900
Maximum
,999980
Range
,876080
Interquartile Range
,124058
Skewness
-3,329
,374
Kurtosis
14,299
,733
Mean
,99633625 ,000878720
95% Confidence Interval for Lower Bound ,99455887
Mean
Upper Bound ,99811363
5% Trimmed Mean
,99706139
Median
,99898500
Variance
Std. Deviation
,000
,005557516
Minimum
,977860
Maximum
,999990
Range
,022130
Interquartile Range
,004328
Skewness
-2,013
,374
Kurtosis
3,527
,733
Universitas Sumatera Utara
87
Tests of Normality
Kolmogorov-Smirnov
Ukuran Varises Esofagus
PLT, ribu/ul
Billirubin Total, mg/dl
AST, unit/L
Albumin, g/L
INR
ALT, mg/dl
Gamma GT, UI/L
AIAG Score
Statistic
df
a
Sig.
Shapiro-Wilk
Statistic
df
Sig.
Kecil
,127
40
,103
,887
40
,001
Besar
,211
40
,000
,781
40
,000
Kecil
,354
40
,000
,642
40
,000
Besar
,228
40
,000
,733
40
,000
Kecil
,277
40
,000
,668
40
,000
Besar
,275
40
,000
,682
40
,000
Kecil
,160
40
,012
,901
40
,002
Besar
,178
40
,003
,955
40
,110
Kecil
,340
40
,000
,331
40
,000
Besar
,161
40
,011
,829
40
,000
Kecil
,263
40
,000
,648
40
,000
Besar
,204
40
,000
,803
40
,000
Kecil
,238
40
,000
,777
40
,000
Besar
,297
40
,000
,740
40
,000
Kecil
,263
40
,000
,628
40
,000
Besar
,255
40
,000
,696
40
,000
a. Lilliefors Significance Correction
Mann-Whitney Test
Ranks
Ukuran Varises Esofagus
PLT, ribu/ul
Billirubin Total, mg/dl
AST, unit/L
N
Mean Rank Sum of Ranks
Kecil
40
52,68
2107,00
Besar
40
28,33
1133,00
Total
80
Kecil
40
33,34
1333,50
Besar
40
47,66
1906,50
Total
80
Kecil
40
33,10
1324,00
Universitas Sumatera Utara
88
Albumin, g/L
INR
ALT, mg/dl
Gamma GT, UI/L
AIAG Score
PLT, ribu/ul
Besar
40
47,90
1916,00
Total
80
Kecil
40
49,85
1994,00
Besar
40
31,15
1246,00
Total
80
Kecil
40
29,24
1169,50
Besar
40
51,76
2070,50
Total
80
Kecil
40
35,23
1409,00
Besar
40
45,78
1831,00
Total
80
Kecil
40
35,41
1416,50
Besar
40
45,59
1823,50
Total
80
Kecil
40
26,40
1056,00
Besar
40
54,60
2184,00
Total
80
Billirubin Total, mg/dl AST, unit/L
Albumin, g/L
INR
Mann-Whitney U
313,000
513,500
504,000
426,000
349,500
Wilcoxon W
1133,000
1333,500
1324,000
1246,000
1169,500
-4,686
-2,757
-2,849
-3,608
-4,336
,000
,006
,004
,000
,000
Asymp. Sig. (2-tailed)
ALT, mg/dl
Gamma GT, UI/L
AIAG Score
Mann-Whitney U
589,000
596,500
236,000
Wilcoxon W
1409,000
1416,500
1056,000
-2,031
-1,958
-5,430
,042
,050
,000
Asymp. Sig. (2-tailed)
Universitas Sumatera Utara
89
ROC Curve
Notes
Output Created
31-JUL-2016 09:54:37
Comments
Input
Data
:PROJECT\STATISTIK\PENY
DALAM\DEDDY\data 31 Juli 2016\data dr
Dedy Interna.sav
Active Dataset
DataSet1
Filter
Weight
Split File
N of Rows in Working Data File
Missing Value
Definition of Missing
Handling
80
User-defined missing values
are treated as missing.
Cases Used
Statistics are based on all cases
with valid
data for all variables in the analysis.
Syntax
ROC AIAG BY ROCGroup (1)
/PLOT=CURVE(REFERENCE)
/PRINT=SE COORDINATES
/CRITERIA=CUTOFF(INCLUDE)
TESTPOS(LARGE)
DISTRIBUTION(FREE) CI(95)
/MISSING=EXCLUDE.
Resources
Processor Time
00:00:00,27
Elapsed Time
00:00:00,24
Case Processing Summary
Ukuran
Varises Esofagus
Valid N (listwise)
a
40
Negative
40
Positive
Larger values of the test result variable(s) indicate
stronger evidence for a positive actual state.
a. The positive actual state is VE Besar.
Universitas Sumatera Utara
90
Area Under the Curve
Test Result Variable(s): AIAG Score
Area
Std. Error
a
symptotic Sig.
b
Asymptotic 95% Confidence Interval
Lower Bound
,853
,044
,000
a.
Under the nonparametric assumption
b.
Null hypothesis: true area = 0.5
Upper Bound
,766
,939
Universitas Sumatera Utara
91
Coordinates of the Curve
Test Result Variable(s): AIAG Score
Positive if Greater Than
Or Equal To
a
Sensitivity
1 - Specificity
,00000000
1,000
1,000
,39314500
1,000
,975
,67206000
1,000
,950
,69134500
1,000
,925
,70428000
1,000
,900
,75376000
1,000
,875
,80025500
1,000
,850
,80418000
1,000
,825
,83699500
1,000
,800
,86703000
1,000
,775
,87196000
1,000
,750
,87842000
1,000
,725
,89095500
1,000
,700
,91012000
1,000
,675
,92098000
1,000
,650
,92589000
1,000
,625
,92956000
1,000
,600
,93523000
1,000
,575
,94415000
1,000
,550
,95067000
1,000
,525
,95660500
1,000
,500
,96129500
1,000
,475
,96480500
1,000
,450
,96959000
1,000
,425
,97372000
1,000
,400
,97620000
1,000
,375
,97753000
1,000
,350
,97963000
,975
,350
,98232000
,950
,350
,98390500
,925
,350
,98497000
,925
,325
,98620000
,900
,325
,98819500
,900
,300
,99092500
,875
,300
,99258000
,850
,300
Universitas Sumatera Utara
92
,99296000
,825
,300
,99354000
,825
,275
,99389000
,825
,250
,99397500
,800
,250
,99402500
,800
,225
,99461000
,775
,225
,99534500
,775
,200
,99560500
,750
,200
,99571000
,725
,200
,99579500
,700
,200
,99626500
,675
,200
,99676500
,650
,200
,99704000
,625
,200
,99736000
,600
,200
,99763000
,600
,175
,99780500
,600
,150
,99816000
,575
,150
,99851500
,575
,125
,99856500
,550
,125
,99867500
,525
,125
,99898500
,500
,125
,99925500
,475
,125
,99940000
,450
,125
,99949000
,400
,125
,99954000
,375
,125
,99966000
,375
,100
,99974500
,350
,100
,99978000
,325
,100
,99982500
,300
,100
,99985000
,275
,100
,99986500
,250
,100
,99988500
,250
,075
,99991500
,225
,075
,99993500
,225
,050
,99995000
,225
,025
,99997000
,200
,025
,99998500
,200
,000
1,00000000
,000
,000
Universitas Sumatera Utara
93
Lampiran 8
Data Hasil Penelitian
No
Nama
Umur
L/P
MR
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
Aman Sidabutar
Arifin Silitonga
Enda Malam
Johanis T
Sahat Sibarani
Netti
Paristono
Sehat Purba
Jamso Hutasoit
Sukiman
Syafiah
Erisa br Siahaan
Hedwar Sibarani
Katiman
Irianto
Jimmy Panjaitan
Joni Indra
Juandy
Marpaung
Kasume
Tambunan
M.Syahni
Tetap
Abd Thalib
Ahmad Kasrun
Andi Ramadani
Apul Sidabutar
Arifin
Aripin Bancin
52
52
40
45
63
47
58
40
52
48
53
58
49
70
61
36
43
33
L
L
P
L
L
P
L
L
L
L
L
P
L
L
L
L
L
L
53
41
52
57
52
23
61
41
43
19
20
21
22
23
24
25
26
27
Bil.
Total
1.2
0.65
2.11
4.71
13.32
9.83
2.53
5.43
32.49
7.31
0.98
0.62
5.13
2.25
4.66
2.66
14.96
0.73
AST
Albumin INR
Asites
HE
CP
586933
596253
593761
593411
544290
588439
589213
587426
544344
592770
590663
620072
559465
618126
410716
548819
621147
605427
Plt.(10
/L)
57
342
23
36
147
60
72
138
380
62
90
33
70
153
94
66
73
433
ø
VE
2
1
2
2
1
2
3
2
1
2
2
3
2
1
3
2
2
1
ALT
3
1
3
3
2
3
2
3
3
3
3
2
3
2
3
3
3
1
Etio.
SH
0
0
1
1
2
0
1
1
2
1
1
2
0
0
1
0
1
0
44
18
61
120
35
1075
200
367
93
166
41
18
88
35
142
47
526
15
2.4
3.1
1.6
1.6
2.8
2.9
2.9
3.1
2.6
2.1
2
2
2.1
2.9
2.7
1.9
3.8
4.5
1.58
0.99
1.75
1.58
1.5
1.39
1.24
1.5
1.21
1.74
1.48
1.19
2.09
0.9
2.11
1.72
1.63
1.47
2
1
3
3
1
2
2
3
2
1
2
2
2
2
2
2
2
1
0
0
1
0
0
0
0
0
0
0
0
0
0
0
0
2
0
0
L
600820
61
0.78
82
2.6
1.72
2
L
L
L
L
L
L
L
L
602903
606204
577673
555770
582156
5438?8
570102
620310
44
363
184
118
266
190
120
112
1.25
8.8
0.3
27.57
16.9
3.91
1.3
2.02
22
111
20
125
320
731
35
176
2.2
2.9
4.9
1.6
2
2
2
3.1
1.4
114
1.1
3.33
1.8
1.14
1.1
1.26
1
2
1
2
2
2
2
2
GGT
AIAG
9
16
38
61
34
106
54
55
77
127
31
15
49
29
100
27
66
15
Grup
ø
2
1
2
2
1
2
2
2
1
2
2
2
2
1
2
2
2
1
106
100
55
68
82
527
456
901
428
37
59
29
39
139
324
991
343
13
0.99948
0.80059
0.99986
0.99948
0.99847
0.99878
0.99552
0.99990
0.99383
0.99981
0.99856
0.98140
0.99999
0.80777
0.99999
0.99999
0.99932
0.97520
0
3
3
2
41
2
68
0.99974
0
0
0
0
0
0
0
0
2
3
1
3
3
3
2
2
0
1
0
0
0
1
1
1
3
1
1
3
1
2
1
2
16
38
16
141
136
236
23
49
2
1
1
2
1
2
1
2
8
179
18
31
358
663
15
492
0.99395
0.95992
0.68173
0.99999
0.99994
0.99785
0.93021
0.99405
Universitas Sumatera Utara
94
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
Armen
Sembiring
Asmara
Sitompul
Hotman
Baini
Bun Ngials
Darmadi
Hutagaol
Daud
Simarmata
Dedi Tarigan
Mariono
Lesmana
Misbah Udin
Nisma Siregar
Nurmansyah
Joni Purba
Rasyad Lubis
Kantin Barus
Koko Saputra
Krisna
Lisria
Sitanggang
Lidia Siahaan
Mestiana
sinurat
Roshidawati S
Rusli Sitepu
Salomo Sitepu
Sanimin
Selamat saragih
Sri Wondo
Wasina
53
L
548865
87
1.49
36
1.5
1.35
3
0
2
0
2
29
2
55
0.99686
72
L
617861
207
10.63
175
2.6
1.16
2
0
3
2
2
76
2
591
0.99722
67
51
54
43
L
L
L
L
468343
555380
623008
604612
426
65
121
108
0.1
0.68
2.17
11.26
15
29
33
175
3.5
2.7
1.7
2.1
1.25
1.1
1.04
1.92
0
1
2
1
0
0
0
0
1
2
3
2
1
0
1
1
1
1
1
2
11
37
19
55
1
1
1
2
39
53
34
86
0.95329
0.92287
0.94025
0.99996
53
L
618951
139
3.58
40
1.7
1.59
2
0
3
0
2
21
2
18
0.99950
46
44
L
L
585645
605782
75
135
20.34
0.43
100
12
1.6
2.7
2.17
0.96
3
1
0
0
3
1
1
0
3
1
38
8
2
1
66
13
0.99999
0.70096
42
55
38
43
65
49
48
40
51
L
P
L
L
L
P
L
L
P
611412
597747
602557
375897
609517
622248
627279
617442
614437
180
154
204
351
406
386
111
60
117
1.19
0.25
1.37
0.25
31.64
27.55
6.04
8.6
2.78
50
31
284
20
506
217
94
53
123
0.5
2.8
3.4
2.7
2.1
2.9
2.9
2.2
1,9
1.45
0.93
1.23
1.02
1.28
0.56
0.93
1.04
2.1
3
2
1
2
2
2
1
1
2
0
0
0
0
0
0
0
0
0
3
2
1
2
3
3
2
3
3
1
0
1
0
1
0
1
0
1
2
1
1
1
2
1
1
1
2
17
13
105
24
61
132
49
37
65
2
1
1
1
2
1
1
1
2
53
26
190
19
228
213
46
17
125
0.99919
0.70760
0.96267
0.79992
0.99667
0.12390
0.66239
0.86622
0.99999
72
41
P
P
594014
622241
674
73
0.38
0.9
47
76
3.1
2
1.02
1.26
2
1
0
2
2
3
0
1
1
2
25
49
1
2
24
60
0.87608
0.98537
48
58
49
64
72
54
55
P
L
L
L
L
P
P
622854
625504
614686
620531
624881
620866
625334
70
126
187
68
134
135
245
7.35
6.18
1.29
11.92
1.13
2.47
0.78
179
89
67
128
75
84
43
2.5
2.1
2.5
1.5
2.4
1.8
2.3
1.73
1.7
1
2.21
1.32
1.85
1.86
3
3
1
2
1
1
1
0
0
0
0
0
0
0
3
3
2
3
2
3
2
1
1
0
1
2
1
1
3
3
1
2
1
2
1
90
38
35
47
85
57
21
2
2
1
2
1
2
1
66
103
302
34
52
41
23
0.99975
0.99984
0.97720
0.99999
0.99517
0.99586
0.99993
Universitas Sumatera Utara
95
55
Aliaman
Tambunan
56 Ngatiah
57 Suhery
58 Mujiburrahman
59 Pandapotan
60 Wagini
61 M.saleh
62 Tuak Sembiring
63 Hj.Sawiyah
64 Z.Bukhari
65 Soden ginting
66 Parlindungan S
67 Wilson S
68 Maria
69 Janinuddin
70 Zunaidah
71 Toguan
72 Asni Narita
73 Hotmaida
74 Arifin Nasution
75 Arjuna Tarigan
76 Edi Susanto
77 Irsan Sihombing
78 Sofi Yusrizal
79 Nuzul Indra
80 Rohana
Keterangan :
62
L
628170
258
2.79
52
2.8
1.22
1
0
2
0
1
17
1
183
0.98703
57
44
35
36
88
57
58
78
59
70
46
57
64
44
49
45
50
42
52
57
45
62
36
33
48
P
L
L
L
P
L
L
P
L
L
L
L
P
L
P
L
P
P
L
L
L
L
P
L
P
547023
511721
515230
520074
618409
630138
512079
618020
608665
631722
632846
593013
600631
580992
615783
628699
538307
619717
597758
553344
564224
330684
595655
624720
620214
271
199
149
156
261
79
232
56
404
79
343
715
161
215
39
389
58
72
93
249
340
88
102
240
87
1.11
1.19
1.31
1.99
14.97
0.73
0.36
1.42
0.15
3.22
0.28
21.17
0.64
2,59
3.94
2.82
2.96
8.97
1.24
17.9
32.18
1.56
0.36
3.46
1.17
92
68
34
47
267
40
71
41
26
110
23
93
74
122
69
489
108
38
19
306
491
455
23
241
46
2.9
2.7
3.4
3
2.4
2.1
3.3
2.8
2.3
2.8
2.5
2
2.8
2.7
2
3.1
1.9
2.1
2.9
2.3
2.1
1.8
2.3
3.1
2.8
0.96
1.4
1.2
1.49
1.03
1.36
1.2
1.03
1.24
1.24
1.71
1.86
1.2
1.07
2.74
1.15
1.76
1.28
1.4
1.29
1.39
1.76
1.08
1.19
1.24
1
1
0
0
2
2
0
1
1
2
0
2
1
1
0
2
2
2
2
3
2
2
1
2
2
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
1
2
1
1
2
2
1
1
1
2
1
2
1
1
2
2
3
3
2
3
3
3
1
2
2
1
1
1
0
0
1
1
0
0
1
0
0
0
1
0
1
1
0
0
1
1
1
0
1
0
1
1
1
1
1
2
1
1
1
2
1
1
1
1
2
1
1
3
3
2
2
1
1
2
3
22
129
53
39
130
28
29
10
25
36
12
58
28
13
31
346
55
37
21
105
127
148
16
46
35
1
1
1
1
1
2
1
1
1
2
1
1
1
1
2
1
1
2
2
2
2
1
1
2
2
213
58
75
25
530
43
121
50
39
128
6
251
19
105
23
289
43
202
11
517
68
42
10
463
107
0.86784
0.99325
0.91909
0.99750
0.99400
0.99569
0.94805
0.98457
0.92891
0.98936
0.99958
0.99998
0.97224
0.90115
0.99999
0.96694
0.99987
0.99267
0.99249
0.99857
0.99573
0.99776
0.88076
0.98324
0.97786
Universitas Sumatera Utara
96
Keterangan:
*) Jenis Kelamin
Laki-laki
=1
Perempuan
=2
*) Asites
tidak ada Asites
Asites minimal
Asites sedang
Asites berat
*) Hepatic Encephalopathy (HE)
Tidak ada HE = 0
HE grade
=1
HE grade
=2
*) Etiologi SH
Bukan Hep. B&C
Hepatitis B
Hepatitis C
Hepatitis B&C
=0
=1
=2
=3
=0
=1
=2
=3
*) Child Pugh
A (Ringan)= 1
B(Sedang)= 2
C(Berat) = 3
*) Varises Esofagus
F1
=1
F2
=2
F3
=3
*) Diameter Grup
Kecil = 1
Besar = 2
Universitas Sumatera Utara