Hasil Uji Deskriptif Usia, Jenis IMT, dan Kelompok PSA Hasil Uji Normalitas Nilai IMT dan Kadar Serum PSA Hasil Uji Korelasi Spearman Hasil Uji Regresi Linier

Lampiran 3 OUTPUT DATA HASIL PENELITIAN

a. Hasil Uji Deskriptif Usia, Jenis IMT, dan Kelompok PSA

Kelompok Usia Frequency Percent Valid Percent Cumulative Percent Valid 50 7 5.6 5.6 5.6 50-59 20 16.0 16.0 21.6 60-69 52 41.6 41.6 63.2 69 46 36.8 36.8 100.0 Total 125 100.0 100.0 IMTgroups Frequency Percent Valid Percent Cumulative Percent Valid Kurus 16 12.8 12.8 12.8 Normal 72 57.6 57.6 70.4 BBLebih 11 8.8 8.8 79.2 Obes 26 20.8 20.8 100.0 Total 125 100.0 100.0 Nilai Kadar PSA kelompok Frequency Percent Valid Percent Cumulative Percent Valid ≤ 4 62 49.6 49.6 49.6 4 63 50.4 50.4 100.0 Total 125 100.0 100.0 Statistics Usia IMT PSA N Valid 125 125 125 Missing Mean 66.02 23.22827 11.9880 Median 67.00 23.23400 4.1000 Mode 69 23.438 .60 Universitas Sumatera Utara

b. Hasil Uji Normalitas Nilai IMT dan Kadar Serum PSA

Tests of Normality Kolmogorov-Smirnov a Shapiro-Wilk Statistic df Sig. Statistic df Sig. IMT .059 125 .200 .992 125 .696 PSA .289 125 .000 .546 125 .000 . This is a lower bound of the true significance. a. Lilliefors Significance Correction Histogram Universitas Sumatera Utara

c. Hasil Uji Korelasi Spearman

Correlations IMT PSA Spearmans rho IMT Correlation Coefficient 1.000 -.368 Sig. 2-tailed . .000 N 125 125 PSA Correlation Coefficient -.368 1.000 Sig. 2-tailed .000 . N 125 125 . Correlation is significant at the 0.01 level 2-tailed. Universitas Sumatera Utara

d. Hasil Uji Regresi Linier

Variables EnteredRemoved a Model Variables Entered Variables Removed Method 1 IMT b . Enter a. Dependent Variable: PSA b. All requested variables entered. Model Summary Model R R Square Adjusted R Square Std. Error of the Estimate 1 .353 a .124 .117 19.92266 a. Predictors: Constant, IMT ANOVA a Model Sum of Squares df Mean Square F Sig. 1 Regression 6939.382 1 6939.382 17.483 .000 b Residual 48820.230 123 396.912 Total 55759.612 124 a. Dependent Variable: PSA b. Predictors: Constant, IMT Coefficients a Model Unstandardized Coefficients Standardized Coefficients t Sig. B Std. Error Beta 1 Constant 59.478 11.497 5.174 .000 IMT -2.044 .489 -.353 -4.181 .000 a. Dependent Variable: PSA Universitas Sumatera Utara Grafik Linier Universitas Sumatera Utara Lampiran 4 Universitas Sumatera Utara Lampiran 5 Universitas Sumatera Utara Universitas Sumatera Utara DAFTAR PUSTAKA Arneth, Borros M., 2009. Clinical Significance of Measuring Prostate-specific Antigen. Labmedicine; 40 8: 487-491 AUA Commentary, 2000. Prostate-specific Antigen Best Practice Policy. Oncology; 142: 267. Brawer MK, Kirby R, 1999. Prostate Specific Antigen ed. 2 nd . Singapore: Health Press Limited Chiang, Andrew S. et al, 2013. Utility of 5-Alpha-Reductase Inhibitors in Active Surveillance for Favourable Risk Prostate Cancer. Can Urol Assoc J; 711-12: 450-4533 Chiu, Peter Ka-Fung et al., 2011. Effect of Body Mass Index on Serum Prostate-Specific Antigen Levels among Patients Presenting with Lower Urinary Tract Symptoms. Asian Pacific Journal of Cancer Prevention; 12:1937-1940 Durmaz, Tahir et al., 2014. Is There a Relationship Between Acute Coronary Syndrome and Prostate Specific Antigen Level?. Urology Journal; 11 1: 1278-1286 Eknoyan, Garabed, 2008. Adolphe Quetelet 1796-1874: The Average Man and Indices of Obesity. Nephrol. Dial. Transplant; 23: 47–51 Erlangga N, Dimas, 2007. Ketepatan Diagnostik Prostat Spesifik Antigen pada Keganasan Prostat di Rumah Sakit Dokter Kariadi Semarang. Semarang: Fakultas Kedokteran Universitas Diponegoro Garrow JS, Webster J., 1985. Quatelet’s Index WH2 as A Measure of Fatness. Int. J. Obes. Related Metabolic Disord.; 9: 147-153 Ganesh, B. et al., 2011. Risk Factors for Prostate Cancer: An Hospital-Based Case-Control Study from Mumbai, India. Indian J Urol.; 273: 345– 350 Ikatan Ahli Urologi Indonesia, 2009. Pedoman Penatalaksanaan BPH di Indonesia. Universitas Sumatera Utara Ikatan Ahli Urologi Indonesia, 2011. Pedoman Penatalaksanaan Kanker Prostat. Joseph E, Oesterling, 1991. Prostate Specific Antigen, a Crucial Assesment of the Most Useful Tumor Markers for Adenocarcinoma of the Prostate. The Journal Of Urology; 145: 907-923. K. O. H, William et al., 2000. Neoplasm of the Prostate. Dalam: C. Bast, Robert et al. Holland - Frei Cancer Medicine 5 th ed.. USA : BC Decker Inc Lee, Sang Hun et al, 2013. Impact of Treatment with Statins on Prostate- Specific Antigen and Prostate Volume in Patients with Benign Prostatic Hyperplasia. Korean Journal of Urology; 54: 750-755 Lilja H. et al, 1991. Prostate-specific Antigen in Serum occurs Predominately in Complex with Α1-anticymptrypsin. Clin. Chem., 37: 1618-1625 Lionel L, Banez et al, 2007. Obesity-related Plasma Hemodilution and PSA Concentration among Men with Prostate Cancer. The Journal of the American Medical Association; 298: 2275–2280. Montironi R, Mazzucchelli R, Algaba F., 2000. Prostate-specific Antigen as a Marker of Prostate Disease. Virchows Arch.; 436: 297-304. Muller, Heiko et al, 2009. Association of Diabetes and Body Mass Index with Levels of Prostate-specific Antigen: Implications for Correction of Prostate-specific Antigen Cutoff Values. Cancer Epidemiol Biomarkers Prev; 18: 1350-1356 Partin, Alan W.. et al. 2012. Campbell-Walsh Urology, Tenth Edition: Prostate. Amerika: Elsevier Saunders Soegondo, Sidartawan Purnamasari, Dyah, 2006. Sindrom Metabolik. Dalam: Sudoyo, Aru W. dkk., 2009. Buku Ajar Ilmu Penyakit Dalam jilid III ed. 5. Jakarta: Pusat Penerbitan Departemen Ilmu Penyakit Dalam Fakultas Kedikteran Universitas Indonesia Tanagho, Emil A., McAninch, Jack W., 2008. Smith’s General Urology edisi 17: Anatomy of the Genitourinary Tract. San Francisco: The McGraw- Hill Companies, Inc. Universitas Sumatera Utara WHO, 2000. Technical Report Series 894; Obesity; Preventing and Managing the Global Epidemic. Swiss: WHO WHO. BMI Classification. Di akses pada: 26 Mei 2014. Dari: http:apps.who.intbmiindex.jsp?introPage=intro_3.html Universitas Sumatera Utara BAB 3 KERANGKA KONSEP DAN DEFINISI OPERASIONAL

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