CONCLUSION ICTS2005 The Proceeding

Information and Communication Technology Seminar, Vol. 1 No. 1, August 2005 ISSN 1858-1633 2005 ICTS 22 captured using similar films andor exposure levels. Hence, to minimize bias, we used a leave-one-woman- out strategy in training. The result is shown in a form of confusion matrices.

5. RESULTS AND DISCUSSION

The result is presented in a confusion matrix as in Table 1. The results showed an agreement of 38.33 in comparison with expert assessment and 78.33 when minor classifications deviation is allowed. The low rate of agreement is below the reported state of the art, which comes partially as a surprise as some of the state of the art work relies on information extracted from single histograms. Table 1. Comparison between automatic, histogram based, and expert classification. Within the tables the proportion of dense tissue is represented as 1: 0, 2: 0-10, 3: 11-25, 4: 26-50, 5: 51- 75, and 6: 76-100. Instead of taking all six classes into account, for mammographic risk assessment it might be more appropriate to just take high and low density estimation classes into consideration, which means that the lower and higher three SCC classes are grouped together. Using such an approach the developed techniques shows an agreement of 80 with the expert assessment. We had applied this methodology into MIAS database [10], and an agreement of 55.17 for SCC and 61.56 for triple MIAS categories were achieved [8]. The latest was similar to those reported by Masek et al. [7], i.e 62.42 when using an Euclidean distance. Their method is based on direct distance measures of average histogram of original images for each density class. It should be noted that we used less data for training due to leave-one-woman-out strategy. Moreover, this is inline with our own single histogram h results, which were 61,99 for triple MIAS classification and 57,14 for SCC based classification. These results might indicate there is little benefit in using the multi-resolution histogram approach. It should be noted that our methodology slightly deviated from Hadjidemetriou et al [5]. Their implementation of the multi-scale approach includes a subsampling step which makes a second normalization essential. In our case, we only using smoothing stage of the multi-scale approach without the subsampling. As such the second normalization step is not used. Despite that multi-resolution histogram technique is claimed to be robust to match either synthetic, Brodatz, or CUReT textures [5], our results could not confirm its application in mammographic density classification. We would like to investigate whether this is caused by nature of the mammographic texture patterns andor imaging system effects. Thus, additional pre-processing to enhance the contrast between fatty and dense tissue, or to incorporate the X-ray imaging protocol information, are areas of future research.

6. CONCLUSION

We have presented an approach to mammographic density classification, which uses multi-resolution histogram information. It was shown that the approach was insufficient when compared to the gold standard provided by an expert radiologist, but when minor classifications errors are allowed it provides a performance of 78.33. Future work will include texture information. ACKNOWLEDGMENT We gratefully acknowledge Dr. Lilian Blot of School of Computing, University of East Anglia, UK for automatic detection of breast boundary tools. REFERENCE [1] NF Boyd, JW Byng, RA Jong, EK Fishell, LE Little, AB Miller, GA Lockwood, DL Tritchler, and Martin J. Yaffe. Quantitative classification of mammographic densities and breast cancer risk: results from the Canadian national breast screening study. Journal of the National Cancer Institute, 879:670.675, May 1995. [2] JW Byng, NF Boyd, E Fishell, RA Jong, and Martin J. Yaffe. The quantitative analysis of mammographic densities. Physics in Medicine and Biology, 39:1629.1638, 1994. [3] FUJIFILM. The fundamentals of medical radiography. In FUJIFILM Technical Handbook: Medical X-ray System. Fuji Photo Film Co., Ltd, 2003. [4] FUJIFILM. Fundamentals of sensitized materials for radiography. In FUJIFILM Technical Handbook: Medical X-ray System. Fuji Photo Film Co., Ltd, 2003. [5] Efstathios Hadjidemetriou, Michael D. Grossberg, and Shree K. Nayar. Multiresolution histograms and their use for recognition. IEEE Transactions on Pattern Analysis and Machine Intelligence, 267:831- 847, July 2004. [6] Nico Karssemeijer. Automated classification of parenchymal patterns in mammograms. Mammographic Density Classification Using Multiresolution Histogram Technique – Izzati Muhimmah, Erika R.E. Denton, Reyer Zwiggelaar ISSN 1858-1633 2005 ICTS 23 Physics in Medicine and Biology, 43:365-378, 1998. [7] M Masek, SM Kwok, CJS deSilva, and Y Attikiouzel. Classification of mammographic density using histogram distance measures. CD-ROM Proceedings of the World Congress on Medical Physics and Biomedical Engineering, page 1, August 2003. [8] Izzati Muhimmah, Erika R.E Denton, and Reyer Zwiggelaar. Histograms in breast density classification: Are 4 better than 1? Seminar Nasional Aplikasi Teknologi Informasi 2005, pages D13-D15, June 2005. [9] Radhika Sivaramakhrishna, N. A. Obuchowski, W. A. Chilcote, and K. A. Powell. Automatic segmentation of mammographic density. Academic Radiology, 83:250-256, March 2001. [10] J Suckling, J Parker, D Dance, S Astley, I Hutt, C Boggis, I Ricketts, E Stamatakis, N Cerneaz, S Kok, P Taylor, D Betal, and J Savage. The mammographic images analysis society digital mammogram database. Exerpta Medica. International Congress Series, 1069:375-378, 1994. [11] John N. Wolfe. Risk for breast cancer development determined by mammographic parenchymal pattern. Cancer, 37:2486-2492, 1976. [12] Chuan Zhou, Heang-Ping Chan, Nicholas Petrick, Mark A. Helvie, Mitchell M. Goodsitt, Berkman Sahiner, and Lubomir M Hadjiiski. Computerized image analysis: Estimation of breast density on mammograms. Med Phys, 286:1056-1069, June 2001. Information and Communication Technology Seminar, Vol. 1 No. 1, August 2005 ISSN 1858-1633 2005 ICTS 24 ANN SOFT SENSOR TO PREDICT QUALITY OF PRODUCT BASED ON TEMPERATURE OR FLOW RATE CORRELATION Totok R. Biyanto Engineering Physic Dept. - FTI – ITS Surabaya Kampus ITS Keputih, Sukolilo, Surabaya 60111 Tell: 62 31 5947188 Fax: 62 31 5923626 Email: totokrbep.its.ac.id ABSTRACT Analizer has slow respon performance, lack of reliability, and expensive, then inferensial measurement by using temperature measurement, reflux flow rate and reboiler steam flow rate are usualy the best way to predict it. This paper will describe Artificial Neural Network ANN soft sensor capability to predict mole fraction Distillate Xd and mole fraction bottom product Xb at binary distillation column. Inferensial measurement could built by using reflux flowrate and reboiler steam flowrate at LV structure, by using smart positioner feedback signal, or by measuring tray temperature. Soft sensor which using tray temperature correlation or flow rate correlation have good Root Mean Square Error RMSE. So, the conclusion is application of ANN soft sensor can build using temperature or flow rate correlation, depend on control strategy or sensor availability. Key-words: ANN soft sensor, composition prediction, temperature and flow rate.

1. INTRODUCTION