W. Hecht Mares Mittal Pupaibool, T. Kottom, A. H. Limper; Mayo Clinic, Rochester, MN. F-814 LaFleur

98 SCIENTIFIC SESSIONS September 9-12 | E-807 Susceptibilities of Clostridium difficile to CB-183,315 and Comparators L. Chesnel 1 , A. E. Crist, Jr 2 , R. M. Patti, JD 2 , D. R. Snydman 3 , J. Kishel 1 ; 1 Cubist Pharmaceuticals, Lexington, MA, 2 York Hosp., York, PA, 3 Tufts Med. Ctr., Boston, MA. E-808 In Vitro Activity of Cadazolid against 209 Toxigenic Isolates of Clostridium difficile

D. W. Hecht

1,2 , D. N. Gerding 1,2 , J. R. Osmolski 1 , S. Sambol 1 , A. Cheknis, BA 2 ; 1 Loyola Univ. Med. Ctr., Maywood, IL, 2 Hines Veterans Admin. Hosp., Hines, IL. ------------------------------------------------------------------------ 096 F Poster Session New Antifungal Agents Monday, 11:15 a.m.–1:15 p.m. . . . . . . . . . . . . . . . . . . . Halls A-C Presentations: F-809 Antifungal Activities of a Novel Arylamidine T-2307 against Azole-Resistant Aspergillus Species, A. calidoustus K. Yamashita, E. Yamada, M. Kaeriyama, H. Nishikawa, N. Fujino, N. No- mura, J. Mitsuyama; Res. Lab., Toyama Chemical Co.,Ltd., Toyama, Japan. F-810 Antifungal Spectrum, In Vivo Efficacy and Structure Activity Relationship of Ilicicolin H S. Singh, W. Liu, X. Li, T. Chen, A. Shafiee, D. Card, G. Abruzzo, A. Flattery, C. Gill, J. Thompson, M. Rosenbach, S. Dreikorn, V. Hornak, M. Meinz, R. Kelly, J. Onishi; Merck Co., Inc., Rahway, NJ. F-811 Comparative In Vitro Activities of Fluconazole, Voriconazole, and MXP-4509 against 256 Candida Isolates from Romanian Tertiary Hospitals

M. Mares

1 , V. Nastasa 1 , R. Moraru 1 , B. Minea 2 , L. Miron 1 ; 1 Ion Ionescu de la Brad Univ., IASI, Romania, 2 Petru Poni Inst. of Macromolecular Chemistry, IASI, Romania. F-812 Sulphur Containing Acetamide, from an Endophytic Fungus Emericella sp. Isolated From Azadirachta indica

S. Mittal

1,2 , S. Kumar 1 , S. Gowil 1 , D. Shrivastava 1 ; 1 Jaipur Natl Univ, Jaipur, India, 2 Amol Pharmaceuticals Pvt. Ltd., Jaipur, India. F-813 Biochemical Evaluation of Rtt109 Inhibitor as a Potential Anti-Fungal Agent J. Pupaibool, T. J. Kottom, A. H. Limper; Mayo Clinic, Rochester, MN. F-814 Milbemycins: Not Just Fungal ABC-Transporter Inhibitors Withdrawn F-815 Antifungal Properties of 2-Adamantanamine, a Potentiator of Azole Antifungals

M. LaFleur

1,2 , L. Long 3 , M. Ghannoum 3 , J. North 4 , R. Lee 4 , K. Lewis 2 ; 1 Arietis Corp., Boston, MA, 2 Northeastern Univ., Boston, MA, 3 Case Western Reserve Univ., Cleveland, OH, 4 St. Jude Children’s Res. Hosp., Memphis, TN. F-816 Potent Fungicidal Activity of Bis-Amidine Antibiotics T. J. Opperman, S. M. Kwasny, S. Nguyen, J. D. Williams, N. P. Peet, T. L. Bowlin; Microbiotix, Inc., Worcester, MA. F-817 ASP9726, A Unique 2nd Generation Echinocandin 1, Discovery of a Novel In Vitro Marker Correlated with In Vivo Anti-Aspergillus Efficacy T. Nakai, S. Matsumoto, S. Uchida, S. Takeda, S. Akamatsu, K. Maki; Astellas Pharma Inc., Tsukuba, Japan. F-818 ASP9726, A Unique 2nd Generation Echinocandin 2 - Synthesis and In Vitro Activity H. Morikawa, A. Okada, M. Tomishima, N. Kayakiri, D. Barrett, S. Akamatsu, S. Matsumoto, S. Uchida, T. Nakai, S. Takeda, K. Maki; Astellas Pharma Inc., Tsukuba, Ibaraki, Japan. F-819 ASP9726, A Unique 2nd Generation Echinocandin 3 - In Vitro and In Vivo Activity against Aspergillus spp. S. Akamatsu, S. Matsumoto, S. Uchida, T. Nakai, S. Takeda, K. Maki, A. Okada, N. Kayakiri, D. Barret; Astellas Pharma Inc.,, Tsukuba, Ibaraki, Japan. F-820 ASP9726, A Unique 2nd Generation Echinocandin 4 - In Vitro and In Vivo Activity against Candida spp. S. Akamatsu, S. Matsumoto, S. Uchida, T. Nakai, S. Takeda, K. Maki, H. Morikawa, M. Tomishima, D. Barrett; Astellas Pharma Inc.,, Tsukuba, Ibaraki, Japan. F-821 ASP9726, a Unique 2nd Generation Echinocandin 5 -In Vitro and In Vivo Activity of Combination Therapy with Voricon- azole against Aspergillus fumigatus S. Akamatsu, S. Matsumoto, S. Uchida, BS , T. Nakai, S. Takeda, K. Maki; Astellas Pharma Inc., Tsukuba, Ibaraki, Japan. F-822 Evaluation of ASP9726 on Glucan Synthase Inhibition from Echinocandin Susceptible and Resistant Fungi

P. Paderu