Deane Saginur J. Bispo, A. C. Pignatari, A. L. Hofling-Lima; Federal Univ. of Sao Paulo, São Paulo, Brazil. D. Berti J. Bergman A. Karlowsky aureus

152 SCIENTIFIC SESSIONS September 9-12 | E-1472 Beta-Lactams BL Enhance Vancomycin Killing Activity against Clinical Methicillin-Resistant Staphylococcus aureus MRSA In Vitro T. Dilworth, J. Sliwinski Candidate, K. Ryan Candidate, M. Dodd, R. C. Mercier; Univ. of New Mexico, Albuquerque, NM. E-1473 The Combination of Iron Chelation and Vancomycin is Synergistic against Staphylococcus aureus In Vitro

G. Luo, T. Ghebremariam, H. Lee, A. Bayer, A. S. Ibrahim; Harbor-UCLA Med. Ctr., Torrance, CA.

E-1474 Activity of PMX-30063 against Drug Resistant Staphylococci

R. Scott

1 , B. Korczak 1 , D. Jorgensen 1 , S. Hawser 2 , M. Hackel 3 , S. Bouchil- lon 3 , Y. Xiong 4,5 , A. Bayer 5 ; 1 PolyMedix, Inc., Radnor, PA, 2 IHMA Europe, Epalinges, Switzerland, 3 IHMA, Inc., Schaumberg, IL, 4 LA Biomed Res. Inst, Torrance, CA, 5 Geffen Sch. of Med., Torrance, CA. E-1475 Ceftaroline Activity against Community Associated CA and Healthcare Associated HA Methicillin-Resistant Staphylococcus aureus MRSA Withdrawn E-1476 Daptomycin D Tigecycline T is Bactericidal against a High Inoculum of Methicillin-Resistant Staphylococcus aureus MRSA with Reduced Susceptibilities to Vancomycin V Up to 120 Hours in a Hollow Fiber Infection Model HFIM T. P. Lim 1,2 , N. Tahir, Dip 1 , W. Lee 1 , S. Sasikala 1 , Y. Cai 1 , L. Y. Hsu 2 , T. Y. Tan 3 , A. L. Kwa 1 ; 1 Singapore Gen. Hosp., Singapore, Singapore, 2 Natl. Univ. Hosp. System, Singapore, Singapore, 3 Changi Gen. Hosp., Singapore, Singapore. E-1477 In Vitro Activity of Fosfomycin Alone and Combination with TrimethoprimSulfamethoxazole against Blood Isolates of Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus A. Leelarasamee, T. Yungyuen, U. Kijsinthopchai, P. Disthaporn, A. Leelaporn; Mahidol Univ., Bangkok, Thailand. E-1478 Combination of Daptomycin with ơ-Lactams Increases the Antibacterial Efficacy against Clinically Relevant MRSA Strains and Prevents Selection of Dap-Resistant Derivatives C. Singh, K. B. Plata, P. Chanda, S. Riosa, R. Rosato, A. Rosato; The Methodist Res. Inst., Houston, TX. E-1479 In Vitro Activity Profile of Tedizolid TZD and Correlations with Linezolid LZD Activity against Recent Staphylococcal Isolates

J. Deane

1 , A. Simenauer 1 , K. Bartizal 2 , K. Shaw 2 , D. Sahm 1 ; 1 Eurofins, Chantilly, VA, 2 Trius Therapeutics, San Diego, CA. E-1480 Biofilm Multiple Combination Bactericidal Test MCBT on Methicillin-Resistant Staphylococcus aureus MRSA from Patients with Cystic Fibrosis CF

R. Saginur

1 , W. Ferris 2 , L. Hyde 2 , R. Slinger 2 , F. Chan 2 ; 1 The Ottawa Hosp., Civic Campus, Ottawa, Canada, 2 CHEO, Ottawa, Canada. E-1481 Vancomycin MIC Creep among Ocular Staphylococcus aureus Isolates

P. J. Bispo, A. C. Pignatari, A. L. Hofling-Lima; Federal Univ. of Sao Paulo, São Paulo, Brazil.

E-1482 Seesaw Effect Between Daptomycin DAP and Macrolide- Lincosamide-Streptogramin MLS Resistance in MRSA

A. D. Berti

1 , W. Rose 1 , G. Sakoulas 2 ; 1 Univ. Wisconsin-, Madison, WI, 2 Univ. California, San Diego, CA. E-1483 In Vitro Susceptibility and Tolerance of Staphylococcus aureus Small Colony Variants to Beta-Lactam Antibiotics E. A. Idelevich 1 , A. Kriegeskorte 1 , C. von Eiff 1,2 , G. Peters 1 , K. Becker 1 ; 1 Univ. Hosp. Münster, Münster, Germany, 2 Pfizer Pharma GmbH, Berlin, Germany. E-1484 Retapamulin Activity against S. aureus Resistant to Various Antimicrobial Agents L. D. Saravolatz, Sr., J. Pawlak, S. Saravolatz, L. B. Johnson; St John Hosp. and Med. Ctr., Grosse Pointe Woods, MI. E-1485 Sequential Versus Simultaneous Exposure to Combination Therapy for Methicillin-Resistant Staphylococcus aureus mrsa Biofilms

S. J. Bergman

1 , K. A. Luciano 2 , V. Sundareshan 2 ; 1 Southern Illinois Univ. Edwardsville, Springfield, IL, 2 Southern Illinois Univ., Springfield, IL. E-1486 Phylogenetic Analysis of Enoyl-ACP Reductase ENR Protein Sequences from 123 Bacterial Species and Demonstration of Staphylococcal-Specific Inhibition by the FabI ENR Inhibitor AFN-1252 Using Reference In Vitro Susceptibility Testing

J. A. Karlowsky

1 , N. Kaplan 2 , B. Hafkin 2 , D. J. Hoban 1 , G. G. Zhanel 1 ; 1 Univ. of Manitoba, Winnipeg, Canada, 2 Affinium Pharmaceuticals, Toronto, Canada. ------------------------------------------------------------------------ 175 F Poster Session Antimicrobial Peptides and Peptidomimetics Tuesday, 11:15 a.m.–1:15 p.m. . . . . . . . . . . . . . . . . . . . Halls A-C Presentations: F-1487 Antimicrobial Peptide Epidermicin Protects Galleria Mellonella Larvae from Experimental Infection with

S. aureus

T. Gibreel, M. Upton; Univ. of Manchester, Manchester, United Kingdom. F-1488