A. Hickman, D. Hughes, C. Malmberg, O. Cars; Uppsala Univ., Uppsala, Sweden. pneumoniae: Comparison Between the Checkerboard and Etest Methods Tängdén B. Gaspar J. B. Melchers, Other

97 MONDAY SCIENTIFIC SESSIONS Final Program E-788 Synergistic Activity of Polymyxin B Associated with Vancomycin or Imipenem against OXA-143, OXA-23, OXA-58, and OXA-72-Producing Acinetobacter baumannii

M. Medeiros, N. Lincopan; Univ. de São Paulo, São Paulo, Brazil. E-789

Seeking Active Agents against KPC-Producing Acinetobacter baumannii KPCAB

K. S. Thomson

1 , I. E. Robledo 2 , G. J. Vázquez 2 ; 1 Creighton Univ. Sch. of Med., Omaha, NE, 2 Univ. Puerto Rico, San Juan, PR. E-790 In Vitro Activity of Tobramycin and Polymyxin E against Pseudomonas aeruginosa PAO1 and 25668

K. M. Tarquinio

1,2 , K. L. Confreda 1 , K. L. LaPlante 3,4 ; 1 Rhode Island Hosp. Pediatric Critical Care Med., Providence, RI, 2 Brown Univ., Provi- dence, RI, 3 Providence VA ID Res. Program, Providence, RI, 4 Univ. of Rhode Island Coll. of Pharmacy, Kingston, RI. E-791 Amikacin A Meropenem M Polymyxin B P is Bactericidal against Pandrug-Resistant PDR Pseudomonas aeruginosa PA Suppress the Emergence of Resistance up to 120 hours in a Hollow Fiber Infection Model HFIM T. P. Lim 1,2 , S. Sasikala 1 , W. Lee 1 , T. Y. Tan 3 , L. Y. Hsu 2 , T. T. Tan 1 , A. L. Kwa 1 ; 1 Singapore Gen. Hosp., Singapore, Singapore, 2 Natl. Univ. Hosp. System, Singapore, Singapore, 3 Changi Gen. Hosp., Singapore, Singapore. E-792 Porin Expression Predicts Responses of Carbapenemase- Producing Klebsiella pneumoniae KPC to the Combination of Doripenem DOR+Ertapenem ERT+Colistin COL In Vitro

J. H. Hong

1 , S. Cheng 2 , R. Shields 1 , Y. Doi 1 , L. Chen 3 , Y. Zhao 3 , B. N. Kreiswirth 3 , C. Clancy 1 , M. H. Nguyen 1 ; 1 Univ. of Pittsburgh Med. Ctr., Pittsburgh, PA, 2 Univ. of Pittsburgh, Pittsburgh, PA, 3 Publ. Hlth. Res Inst., Univ. of Med. Den. of NJ, Newark, NJ. E-793 Bactericidal Activity of Multiple Combinations of Fosfomycin and Colistin against NDM-1 Producing Enterobacteriaceae M. S. Albur, A. R. Noel, K. E. Bowker, A. P. MacGowan; North Bristol NHS Trust, Bristol, United Kingdom. E-794 In Vitro Activity of Colistin Alone and in Combination with Doripenem against KPC-Producing

K. pneumoniae Isolates

G. C. Lee

1,2 , D. S. Burgess 1,2 ; 1 Univ. of Texas Col. of Pharmacy, Austin, Texas, 2 UT Hlth. Sci. Ctr., San Antonio, Texas. E-795 Optimizing Polymyxin POL Combinations Combos with ‘Old’ Antibiotics against NDM-Producing Klebsiella pneumoniae Kp H. J. Lee 1 , K. Davis 1 , C. Ku 1 , H. H. Yu 1 , A. Poudyal 1 , J. Jacob 1 , B. Y. Liu 2 , J. Fu 2 , D. L. Paterson 3 , R. L. Nation 1 , J. Li 1 ; 1 Monash Inst. of Pharmaceuti- cal Sci., Monash Univ., Melbourne, Australia, 2 Monash Univ., Melbourne, Australia, 3 Univ. of Queensland Ctr. for Clin. Res., Brisbane, Australia. E-796 Synergistic Activity of Colistin COL Plus Rifampin RIF against COL-Resistant R and Susceptible S KPC-Producing Klebsiella pneumoniae KPC-KP Clinical Isolates

E. Tagliaferri

1 , C. Tascini 1 , S. Flammini 1 , T. Giani 2 , A. Leonildi 1 , I. Ciullo 1 , G. Rossolini 2 , F. Menichetti 1 ; 1 Azienda Ospedaliera Univ. Pisana, Pisa, Italy, 2 Univ. di Siena, Siena, Italy. E-797 In Vitro Activity of Daptomycin in Combination with Low- Dose Colistin Versus a Diverse Collection of Gram-Negative Bacterial Pathogens

L. Phee, M. Hornsey, D. Wareham; QMUL, London, United Kingdom. E-798

Novel Antibiotic Combinations with Enhanced Antibacterial Effect against ESBL- Producing E.coli and Klebsiella pneumoniae

R. A. Hickman, D. Hughes, C. Malmberg, O. Cars; Uppsala Univ., Uppsala, Sweden.

E-799 In Vitro Activities of Tigecycline and Tigecycline Combi- nations against KPC-Producing

K. pneumoniae: Comparison Between the Checkerboard and Etest Methods

V. Papoutsaki, D. Lekkakou, I. Galani, M. Souli, L. Galani, I. Karaiskos, N. Vakalis, H. Giamarellou; Hygeia Hosp., Athens, Greece. E-800 Synergistic Effect of Aztreonam Combinations against VIM- and NDM-Producing Klebsiella pneumoniae

T. Tängdén

1 , R. A. Hickman 1 , P. Forsberg 1 , C. G. Giske 2 , P. Lagerbäck 1 , O. Cars 1 ; 1 Uppsala Univ., Uppsala, Sweden, 2 Karolinska Inst., Stockholm, Sweden. E-801 Potential Antiseptic Properties of Dioctadecyldimethylam- monium Bromide Cationic Bilayer Fragments DDA-BF against Carbapenemase-Producing Bacteria

E. B. Gaspar

1 , A. S. Rosetti 2 , H. G. Turano 2 , M. Medeiros 2 , P. R. Neves 2 , N. Lincopan 2 ; 1 Embrapa, Bagé, Brazil, 2 São Paulo Univ., São Paulo, Brazil. E-802 The Effect of Urine, Lung Surfactant and Testing Parameter Variations on the In Vitro Activity of GSK2251052 and Merope- nem L. M. Koeth 1 , J. DiFranco-Fisher 1 , N. E. Scangarella-Oman 2 ; 1 Lab. Spe- cialists, Inc., Westlake, OH, 2 GlaxoSmithKline, Collegeville, PA. E-803 Comparative In Vitro Activity of Doripenem, Meropenem and Imipenem in a Prospective Multi-Centre Study

M. J. B. Melchers, Other

1 , A. Voss 2 , J. A. Kluytmans 3 , C. van Mil 2 , J. W. Mouton 1 , the Design study group; 1 Radboud Univ. Nijmegen Med. Ctr, Ni- jmegen, Netherlands, 2 Canisius Wilhelmina Hosp., Nijmegen, Netherlands, 3 Amphia Hosp., Breda, Netherlands. E-804 Discrepancies Between Colistin COL MICs and Inhibition of Acinetobacter Ab and Klebsiella Kp During Time-Kill Assays TKA R. K. Shields, C. J. Clancy , E. G. Press, J. Hong, C. A. Updike, M. H. Nguyen; Univ. of Pittsburgh, Pittsburgh, PA. Late-breaker presentations are listed behind the Late-breaker tab of the Final Program. ------------------------------------------------------------------------ 095 E Poster Session In Vitro Activity Versus Anaerobes Monday, 11:15 a.m.–1:15 p.m. . . . . . . . . . . . . . . . . . . . Halls A-C Presentations: E-805 Patterns of Resistance in Bacteroides fragilis Group: Analysis of Period 2010-2012 in a Teaching Hospital of Madrid Spain F. J. Candel, E. Baos, P. Merino, F. De la Torre, E. Culebras, J. J. Picazo; Hosp. Clinico San Carlos, Madrid, Spain. E-806 In Vitro Activity of Twelve Antianaerobic Agents against Clin- ical Veillonella sp. Strains Isolated Over a 4-Year Period 2008-11 L. Alcalá , T. Peláez, P. Martín-Rabadán, E. Reigadas , E. Bouza; Hosp. GU Gregorio Marañón, Univ. Complutense de Madrid., Madrid, Spain. 98 SCIENTIFIC SESSIONS September 9-12 | E-807 Susceptibilities of Clostridium difficile to CB-183,315 and Comparators L. Chesnel 1 , A. E. Crist, Jr 2 , R. M. Patti, JD 2 , D. R. Snydman 3 , J. Kishel 1 ; 1 Cubist Pharmaceuticals, Lexington, MA, 2 York Hosp., York, PA, 3 Tufts Med. Ctr., Boston, MA. E-808 In Vitro Activity of Cadazolid against 209 Toxigenic Isolates of Clostridium difficile

D. W. Hecht