Stojanov, Master of Science - PhD Student D. Schindler, PhD - Postdoctoral Fellow S. Oderinde, Mr, Masters in Medical Laborary Science MMLS - Lecturer

169 TUESDAY SCIENTIFIC SESSIONS Final Program ------------------------------------------------------------------------ 197 C1 Slide Session Resistance in Staphylococcus aureus Tuesday, 11:15 a.m.–12:45 p.m. . . . . . . . . . . . . . . . . . Room 122 UAN: 0391-9999-12-137-L04-P Moderators: Frederic Laurent, MD, PhD - Associate Professor Hopsices Civils de Lyon, Inserm U851, Lyon, France. Rodrigo E. Mendes, PhD - Associated Director JMI Lab., North Liberty, IA. Objectives: Upon the completion of this Slide Session, the participant should be able to: Discuss the emerging antibiotic resistance that’s in Staphylococcus aureus; Discuss several biochemical based mechanisms of resistance; and Understand impact of resistance mechanisms on therapeutic options for staphylococcal infections. Presentations: 11:15 a.m. C1-1739 Human Case of Invasive Osteitis: First Report of Severe Infection Due to a Methicillin-Resistant Staphylococcus aureus Isolate Carrying the Novel meca LGA251 Variant

O. Barraud, PharmD, PhD - Biologist

1,2,3 , F. Laurent, PharmD, PhD - Biologist 4,5 , B. François, MD - Clinician 1,3 , N. Hidri, MD - Biologist 1,3 , C. Martin, PharmD, PhD - Biologist 1,3 , M. Bes, Technician - Technician 4,5 , M. Clavel, MD - Clinician 3 , F. Garnier, PharmD, PhD - Biologist 1,3 , M. Ploy, PharmD, PhD - Professor 1,2 ; 1 INSERM, Limoges, France, 2 Univ. Limoges, Limoges, France, 3 CHU Limoges, Limoges, France, 4 INSERM, Lyon, France, 5 CNR Staphylocoques, Lyon, France. 11:25 a.m. C1-1740 Low Prevalence of Cassette Chromosome Recombinases ccr Genes among Community-Associated Methicillin Susceptible Staphylococcus aureus CA-MSSA Withdrawn 11:25 a.m. C1-1741 Biochemical Mechanisms of Sulfonamide Resistance in Staphylococcus aureus E. C. Griffith, Pharm D - GHS, R. E. Lee, PhD - Member; St. Jude, Memphis, TN. 11:35 a.m. C1-1742 Thickened Cell Wall as a Mechanism for Increased Telavancin Minimum Inhibitory Concentration MIC in Methicillin-Resistant Staphylococcus aureus MRSA

K. Ryan, PharmD Candidate - Research Assistant, S. Jett, PhD - Director,

HSC EM Facility, R. C. Mercier, PharmD - Associate Professor; Univ. of New Mexico, Albuquerque, NM. 11:45 a.m. C1-1743 Divergent Evolution of Methicillin-Resistant Staphylococcus aureus MRSA ST239 in a Patient with Persistent Bacteremia

S. J. van Hal, MBChB, FRACP, FRCPA - Associate Professor

1,2 , J. A. Steen, PhD - Researcher 3,4 , I. B. Gosbell, PhD - Staff Specialist 1,5,2 , B. A. Espedido, PhD - Scientist 1,5 , M. A. Cooper, PhD - Professor 3 , S. M. Grimmond, PhD - Professor 3,4 , S. O. Jensen, PhD - Principal Scientist 1,5 ; 1 Antibiotic Resistance Mobile Elements Group, Sch. of Med., Univ. of Western Sydney, Sydney, Australia, 2 Liverpool Hosp., South West Sydney Local Hlth. District, Sydney, Australia, 3 Inst. for Molecular Bioscience, Univ. of Queensland, Bris- bane, Australia, 4 Queensland Ctr. for Med. Genomics, Univ. of Queensland, Brisbane, Australia, 5 Ingham Inst. for Applied Med. Res., Sydney, Australia. 11:55 a.m. C1-1744 Cell Membrane CM Lipid Profiles Correlate with Daptomycin DAP Resistance R in Methicillin-Resistant Staphylococcus aureus MRSA N. N. Mishra, PhD - Senior Research Associate 1 , A. Rubio, PhD - Scientist 2 , A. S. Bayer, MD - Professor 1,3 ; 1 LA Biomedical Res. Inst. at Harbor UCLA, Torrance, CA, 2 Cubist Pharmaceuticals, Lexington, MA, 3 David Geffen Sch. of Med. UCLA, Los Angeles, CA. 12:05 p.m. C1-1745 Analysis of cfr-Carrying Plasmids in Staphylococcus epidermidis and Staphylococcus aureus from Two Hospitals in Ohio

R. E. Mendes, PhD - Dir

1 , L. M. Deshpande, PhD - Res Scientist 1 , H. F. Bonilla, MD - Professor 2 , M. D. Huband, BS - Senior Principal Scientist 3 , R. N. Jones, MD - CEO 1 , J. P. Quinn, MD - Senior Advisor 3 ; 1 JMI Lab., North Liberty, IA, 2 UPMC Mercy, Pittsburgh, PA, 3 Pfizer Inc, Groton, CT. 12:15 p.m. C1-1746 Dynamics of Excision of the Staphylococcal Cassette Chro- mosome mec SCC mec in Methicillin-Resistant Staphylococcus aureus MRSA

M. Stojanov, Master of Science - PhD Student

1 , P. Moreillon, MD-PhD - Professor 1 , O. Sakwinska, PhD - Researcher 2 ; 1 UNIL, Lausanne Univ., Lausanne, Switzerland, 2 Nestlé Res. Ctr., Lausanne, Switzerland. 12:25 p.m. C1-1747 Expression of Multidrug Resistance Efflux Pump MDR-EP Genes in Clinical and Environmental Isolates of Staphylococcus aureus

B. D. Schindler, PhD - Postdoctoral Fellow

1 , C. Kosmidis, MD - Fellow 2 , P. L. Jacinto, MD - Fellow 2 , D. Patel, MD - Fellow 2 , K. Bains, MD - Fellow 2 , S. M. Seo, MT - Laboratory Associate 1 , G. W. Kaatz, MD - Professor of Medicine 1 ; 1 John D. Dingell VA Med. Ctr., Detroit, MI, 2 Wayne State Univ. Sch. of Med., Detroit, MI. Late-breaker presentations are listed behind the Late-breaker tab of the Final Program. 170 SCIENTIFIC SESSIONS September 9-12 | ------------------------------------------------------------------------ 198 G Slide Session Global Pediatrics Tuesday, 11:15 a.m.–12:45 p.m. . . . . Esplanade Ballroom 309 UAN: 0391-9999-12-138-L04-P Moderators: Karina M. Butler, MB, DCh - Professor Our Lady’s Children’s Hosp., Dublin, Ireland. Mike Sharland, MD - Professor of Paediatric Infectious Diseases St. George’s Hosp. and Med. Sch., London, United Kingdom. Objectives: Upon the completion of this Slide Session, the participant should be able to: Discuss current epidemiology of pediatric infectious diseases on a global scale; Discuss cutting-edge management issues in pediatric infections; and Discuss aspects of the global impact of infections in children. Presentations: 11:15 a.m. G-1748 Multiplication of Coxsackie Bs and Other Non Polio Enteroviruses on L20B Cell Line

B. S. Oderinde, Mr, Masters in Medical Laborary Science MMLS - Lecturer

1,2 , M. M. Baba, PhD - Lecturer 1,2 , A. J. Williams, PhD - Microbiolo- gist 3 , D. N. Bukbuk, Masters - Lecturer 1 , M. J. Bamaiyi, BSc - Technician 2 , M. T. Akinola, BSc - Technologist 2 , J. Dawurung, BSc- Technician 2 , H. Adamu, HND AIMLT - Technologist 2 , T. Muhammed, Masters - Tech- nologist 2 ; 1 Univ. of Maiduguri , Maiduguri, Nigeria, 2 WHO Natl. Polio ITB Lab., Univ. of Maiduguri Teaching Hosp., Maiduguri, Nigeria, 3 CDC, Atlanta, GA. 11:30 a.m. G-1749 A Prospective Observational Study of the Safety and Tolerability of Oseltamivir in Children Aged up to 24 Months

B. Rath