Intoksikasi Amfetamin TINJAUAN PUSTAKA

2. apillary dilation 3. elevated or lowered blood pressure 4. perspiration or chills 5. nausea or vomiting 6. evidence of weight loss 7. psychomotor agitation or retardation 8. muscular weakness, respiratory depression, chest pain, or cardiac arrhythmias 9. confusion, seizures, dyskinesias, dystonias, or coma D. The symptoms are not due to a general medical condition and are not better accounted for by another mental disorder. Specify if: With perceptual disturbances From American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 4th ed. Text rev. Washington, DC: American Psychiatric Association; copyright 2000, with permission.

2.4. Ketergantungan dan Penyalahgunaan Amfetamin Amphetamine

Dependence and Amphetamine Abuse Ketergantungan Amfetamin dapat menyebabkan penurunan yang drastis pada kemampuan seseorang dalam bekerja, mengabaikan kewajibannya dalam keluarga dan meningkatkan stress. Seseorang yang menyalahgunakan Amfetamin membutuhkan dosis yang semakin tinggi untuk mendapatkan efek lebih dan tanda-tanda fisik pada penyalahgunaan Amfetamin seperti penurunan berat badan dan paranoid hampir selalu berkembang dengan penyalahgunaan yang berkelanjutan Sadock, 2007. Tabel 2.2. Tabel Kriteria Diagnosa Penyalahgunaan Zat Menurut DSM IV TR DSM-IV-TR Criteria for Substance Abuse A. A maladaptive pattern of substance use leading to clinically significant impairment or distress, as manifested by one or more of the following, occurring within a 12-month period: 1. recurrent substance use resulting in a failure to fulfill major role obligations at work, school, or home e.g., repeated absences or poor work performance related to substance use; substance-related absences, suspensions, or expulsions from school; neglect of children or household 2. recurrent substance use in situations in which it is physically hazardous e.g., driving an automobile or operating a machine when impaired by substance use 3. recurrent substance-related legal problems e.g., arrests for substance-related disorderly conduct 4. continued substance use despite having persistent or recurrent social or interpersonal problems caused or exacerbated by the effects of the substance e.g., arguments with spouse about consequences of intoxication, physical fights B. The symptoms have never met the criteria for Substance Dependence for this class of substance. From American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 4th ed. Text rev. Washington, DC: American Psychiatric Association; copyright 2000, with permission. Tabel 2.3. Tabel Kriteria Diagnosa Ketergantungan Zat Menurut DSM IV TR DSM-IV-TR Diagnostic Criteria for Substance Dependence A maladaptive pattern of substance use, leading to clinically significant impairment or distress, as manifested by three or more of the following, occurring at any time in the same 12-month period: 1. tolerance, as defined by either of the following: a. a need for markedly increased amounts of the substance to achieve intoxication or desired effect b. markedly diminished effect with continued use of the same amount of the substance 2. withdrawal, as manifested by either of the following: a. the characteristic withdrawal syndrome for the substance refer to Criteria A and B of the criteria sets for Withdrawal from the specific substances b. the same or a closely related substance is taken to relieve or avoid withdrawal symptoms 3. the substance is often taken in larger amounts or over a longer period than was intended 4. there is a persistent desire or unsuccessful efforts to cut down or control substance use 5. a great deal of time is spent in activities necessary to obtain the substance e.g., visiting multiple doctors or driving long distances, use the substance e.g., chain-smoking, or recover from its effects 6. important social, occupational, or recreational activities are given up or reduced because of substance use 7. the substance use is continued despite knowledge of having a persistent or recurrent physical or psychological problem that is likely to have been caused or exacerbated by the substance e.g., current cocaine use despite recognition of cocaine-induced depression, or continued drinking despite

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