74
P1 1 0.543
11.247 562.344 0.562 0.565 0.019
3.384 0.682
82.851 2 0.516
10.687 534.336 0.534 3 0.561
11.620 581.017 0.581 4 0.547
11.330 566.494 0.566 5 0.561
11.620 581.017 0.581
P2 1 0.586
12.139 606.950 0.607 0.599 0.028
4.699 0.675
88.781 2 0.535
11.081 554.046 0.554 3 0.596
12.346 617.324 0.617 4 0.604
12.512 625.622 0.626 5 0.572
11.849 592.427 0.592
P3 1 0.468
9.691 484.544 0.485 0.435 0.086 19.643
0.672 64.788
2 0.433 8.965 448.237 0.448
3 0.493 10.210 510.477 0.510
4 0.428 8.861 443.050 0.443
5 0.281 5.811 290.560 0.291
f. Stabilitas Minggu III Suhu 45
o
C i. Uji Organoleptis
Formula Warna
Kejernihan Kehalusan
Kelengketan
PVP 1 Kuning
Terdispersi Halus
Kering PVP 2
Kuning Terdispersi
Halus Kering
PVP 3 Kuning
Terdispersi Agak kasar ada
gelembung Kering
ii. Uji Keseragaman Bobot
PVP 1 PVP 2
PVP 3
1 0.0097
0.0084 0.0078
2 0.0118
0.0112 0.0073
3 0.0116
0.0131 0.0072
4 0.0072
0.0125 0.0055
5 0.0112
0.0127 0.0141
6 0.0106
0.0088 0.0138
7 0.0107
0.0127 0.0157
8 0.0069
0.0075 0.0083
9 0.0113
0.0098 0.0123
10 0.0065
0.0065 0.0135
�̅
0.00975 0.01032
0.01055
SD 0.0019734
0.0023108 0.0034837
CV 20.24
22.39 33.02
75
iii. Uji Ketebalan
PVP 1 PVP 2
PVP 3
1 0.15
0.15 0.2
2 0.15
0.15 0.2
3 0.15
0.15 0.2
4 0.15
0.15 0.2
5 0.15
0.15 0.2
�̅ 0.15
0.15 0.2
iv. Uji pH Sediaan
pH
PVP 1 7.1
PVP 2 7.3
PVP 3 7.2
v. Uji Moisture Content dan Moisture Absorption
Bobot awal
Bobot akhir
Bobot akhir
MC �̅
MC SD
CV MA
�̅ MA
SD CV
P1 1 0.0097 0.0096 0.0103 1.042 1.015 0.652 64.26
7.292 4.888 3.086
63.126 2 0.0118 0.0116 0.0122 1.724
5.172 3 0.0116 0.0116 0.0118 0.000
1.724 4 0.0072 0.0071 0.0077 1.408
8.451 5 0.0112 0.0111 0.0113 0.901
1.802 P2 1 0.0084 0.0083 0.0084 1.205
1.374 1.021 74.35 1.205
4.540 5.131 113.013 2 0.0112 0.0111 0.0126 0.901
13.514 3 0.0131 0.0128 0.0130 2.344
1.562 4 0.0125 0.0125 0.0130 0.000
4.000 5 0.0127 0.0124 0.0127 2.419
2.419 P3 1 0.0078 0.0077 0.0078 1.299
1.636 1.074 65.66 1.299
5.616 4.900 87.258
2 0.0073 0.0073 0.0083 0.000 13.699
3 0.0072 0.0070 0.0072 2.857 2.857
4 0.0055 0.0054 0.0056 1.852 3.704
5 0.0141 0.0138 0.0147 2.174 6.522
vi. Uji Ketahanan Pelipatan
Frekuensi
PVP 1 42
PVP 2 67
PVP 3 45
76
vii. Uji Kandungan Obat dalam Sediaan
Formula Abs
Kadar Terukur
µgmL Q Obat
µg Q
Obat mg
�̅ Q Obat
SD CV
Q Obat Teoritis
mg Recovery
P1 1 0.591
12.243 612.137 0.612 0.599 0.092 15.372
0.682 87.840
2 0.654 13.550 677.490 0.677
3 0.572 11.849 592.427 0.592
4 0.432 8.944 447.199 0.447
5 0.643 13.322 666.079 0.666
P2 1 0.515
10.666 533.299 0.533 0.498 0.065 13.132
0.675 73.721
2 0.480 9.940 496.992 0.497
3 0.420 8.695 434.751 0.435
4 0.567 11.745 587.241 0.587
5 0.421 8.716 435.788 0.436
P3 1 0.651
13.488 674.378 0.674 0.610 0.079 12.932
0.672 90.721
2 0.656 13.591 679.564 0.680
3 0.596 12.346 617.324 0.617
4 0.469 9.712 485.581 0.486
5 0.571 11.828 591.390 0.591
g. Stabilitas Minggu IV Suhu 37
