76
vii. Uji Kandungan Obat dalam Sediaan
Formula Abs
Kadar Terukur
µgmL Q Obat
µg Q
Obat mg
�̅ Q Obat
SD CV
Q Obat Teoritis
mg Recovery
P1 1 0.591
12.243 612.137 0.612 0.599 0.092 15.372
0.682 87.840
2 0.654 13.550 677.490 0.677
3 0.572 11.849 592.427 0.592
4 0.432 8.944 447.199 0.447
5 0.643 13.322 666.079 0.666
P2 1 0.515
10.666 533.299 0.533 0.498 0.065 13.132
0.675 73.721
2 0.480 9.940 496.992 0.497
3 0.420 8.695 434.751 0.435
4 0.567 11.745 587.241 0.587
5 0.421 8.716 435.788 0.436
P3 1 0.651
13.488 674.378 0.674 0.610 0.079 12.932
0.672 90.721
2 0.656 13.591 679.564 0.680
3 0.596 12.346 617.324 0.617
4 0.469 9.712 485.581 0.486
5 0.571 11.828 591.390 0.591
g. Stabilitas Minggu IV Suhu 37
o
C i. Uji Organoleptis
Formula Warna
Kejernihan Kehalusan
Kelengketan
PVP 1 Kuning
Terdispersi Halus
Kering PVP 2
Kuning Terdispersi
Halus Kering
PVP 3 Kuning
Terdispersi Agak kasar ada
gelembung Kering
ii. Uji Keseragaman Bobot
PVP 1 PVP 2
PVP 3
1 0.0048
0.0141 0.0054
2 0.0095
0.0123 0.0058
3 0.0110
0.0112 0.0152
4 0.0114
0.0188 0.0143
5 0.0103
0.0143 0.0092
6 0.0112
0.0129 0.0144
7 0.0123
0.0204 0.0166
8 0.0113
0.0147 0.0091
9 0.0110
0.0161 0.0068
10 0.0111
0.0172 0.0057
�̅
0.01039 0.0152
0.01025
SD 0.001986
0.0027709 0.0042048
77
CV
19.12 18.23
41.02
iii. Uji Ketebalan
PVP 1 PVP 2
PVP 3
1 0.20
0.20 0.10
2 0.20
0.20 0.10
3 0.20
0.20 0.10
4 0.20
0.20 0.10
5 0.20
0.20 0.10
�̅ 0.20
0.20 0.10
iv. Uji pH Sediaan
pH
PVP 1 7.1
PVP 2 7
PVP 3 7
v. Uji Moisture Content dan Moisture Absorption
Bobot awal
Bobot akhir
Bobot akhir
MC �̅
MC SD
CV MA
�̅ MA
SD CV
P1 1 0.0048 0.0047 0.0048 2.128
1.211 0.870 71.808
2.128 8.836 3.937
44.560 2 0.0095 0.0094 0.0103
1.064 9.574
3 0.0110 0.0110 0.0120 0.000
9.091 4 0.0114 0.0113 0.0126
0.885 11.504
5 0.0103 0.0101 0.0113 1.980
11.881 P2 1 0.0141 0.0139 0.0143
1.439 3.326 2.082
62.579 2.878
1.955 0.859 43.953
2 0.0123 0.0119 0.0120 3.361
0.840 3 0.0112 0.0110 0.0112
1.818 1.818
4 0.0188 0.0182 0.0187 3.297
2.747 5 0.0143 0.0134 0.0136
6.716 1.493
P3 1 0.0054 0.0047 0.0048 14.894 8.695 9.055 104.140
2.128 1.400 1.774 126.739
2 0.0058 0.0048 0.0050 20.833 4.167
3 0.0152 0.0142 0.0142 7.042
0.000 4 0.0143 0.0142 0.0143
0.704 0.704
5 0.0092 0.0092 0.0092 0.000
0.000
vi. Uji Ketahanan Pelipatan
Frekuensi
PVP 1 25
PVP 2 25
78
PVP 3 15
vii. Uji Kandungan Obat dalam Sediaan
Formula Abs
Kadar Terukur
µgmL Q Obat
µg Q
Obat mg
�̅ Q Obat
SD CV
Q Obat Teoritis
mg Recovery
P1 1 0.570
11.807 590.353 0.590 0.571 0.056
9.888 0.682
83.763 2 0.484
10.023 501.141 0.501 3 0.560
11.600 579.979 0.580 4 0.517
10.707 535.373 0.535 5 0.627
12.990 649.481 0.649
P2 1 0.677
14.027 701.349 0.701 0.655 0.088 13.393
0.675 97.080
2 0.556 11.517 575.830 0.576
3 0.545 11.288 564.419 0.564
4 0.747 15.479 773.963 0.774
5 0.638 13.218 660.892 0.661
P3 1 0.509
10.541 527.075 0.527 0.533 0.034
6.394 0.672
79.298 2 0.551
11.413 570.643 0.571 3 0.493
10.210 510.477 0.510 4 0.545
11.288 564.419 0.564 5 0.475
9.836 491.805 0.492
h. Stabilitas Minggu IV Suhu 45
