72
3 0.555 11.496 574.793 0.575
4 0.543 11.247 562.344 0.562
5 0.545 11.288 564.419 0.564
P2 1 0.521
10.790 539.523 0.540 0.540 0.024
4.397 0.675
80.022 2 0.518
10.728 536.411 0.536 3 0.501
10.376 518.776 0.519 4 0.560
11.600 579.979 0.580 5 0.508
10.521 526.037 0.526
P3 1 0.504
10.438 521.888 0.522 0.492 0.159 32.308
0.672 73.185
2 0.295 6.102 305.083 0.305
3 0.339 7.015 350.726 0.351
4 0.597 12.367 618.361 0.618
5 0.640 13.259 662.967 0.663
e. Stabilitas Minggu III Suhu 37
o
C i. Uji Organoleptis
Formula Warna
Kejernihan Kehalusan
Kelengketan
PVP 1 Kuning
Terdispersi Halus
Kering PVP 2
Kuning Terdispersi
Halus Kering
PVP 3 Kuning
Terdispersi Agak kasar ada
gelembung Kering
ii. Uji Keseragaman Bobot
PVP 1 PVP 2
PVP 3
1 0.0128
0.0181 0.0125
2 0.0104
0.0176 0.0126
3 0.0124
0.0216 0.0078
4 0.0106
0.0209 0.0060
5 0.0105
0.0157 0.0082
6 0.0110
0.0138 0.0050
7 0.0110
0.0136 0.0111
8 0.0116
0.0154 0.0110
9 0.0120
0.0143 0.0068
10 0.0120
0.0121 0.0084
�̅
0.01143 0.01631
0.00894
SD 0.000805
0.0030088 0.0025664
CV 7.04
18.45 28.71
iii. Uji Ketebalan
PVP 1 PVP 2
PVP 3
1 0.15
0.15 0.15
73
2 0.15
0.15 0.15
3 0.15
0.15 0.15
4 0.15
0.15 0.15
5 0.15
0.15 0.15
�̅
0.15 0.15
0.15
iv. Uji pH Sediaan
pH
PVP 1 7.2
PVP 2 7.2
PVP 3 7.2
v. Uji Moisture Content dan Moisture Absorption
Bobot awal
Bobot akhir
Bobot akhir
MC �̅
MC SD
CV MA
�̅ MA
SD CV
P1 1 0.0128 0.0125 0.0131 2.400
1.429 1.220 85.41
4.800 6.139 2.593 42.233
2 0.0104 0.0101 0.0111 2.970
9.901 3 0.0124 0.0123 0.0131
0.813 6.504
4 0.0106 0.0106 0.0113 0.000
6.604 5 0.0105 0.0104 0.0107
0.962 2.885
P2 1 0.0181 0.0176 0.0185 2.841
1.909 2.004 104.98 5.114
3.596 1.309 36.392 2 0.0176 0.0175 0.0183
0.571 4.571
3 0.0216 0.0215 0.0223 0.465
3.721 4 0.0209 0.0199 0.0203
5.025 2.010
5 0.0157 0.0156 0.0160 0.641
2.564 P3 1 0.0125 0.0119 0.0126
5.042 4.692 3.633
77.43 5.882
4.753 3.070 64.593 2 0.0126 0.0122 0.0127
3.279 4.098
3 0.0078 0.0076 0.0078 2.632
2.632 4 0.0060 0.0059 0.0060
1.695 1.695
5 0.0082 0.0074 0.0081 10.811 9.459
vi. Uji Ketahanan Pelipatan
Frekuensi
PVP 1 25
PVP 2 35
PVP 3 20
vii. Uji Kandungan Obat dalam Sediaan
Formula Abs
Kadar Terukur
µgmL Q Obat
µg Q
Obat mg
�̅ Q Obat
SD CV
Q Obat Teoritis
mg Recovery
74
P1 1 0.543
11.247 562.344 0.562 0.565 0.019
3.384 0.682
82.851 2 0.516
10.687 534.336 0.534 3 0.561
11.620 581.017 0.581 4 0.547
11.330 566.494 0.566 5 0.561
11.620 581.017 0.581
P2 1 0.586
12.139 606.950 0.607 0.599 0.028
4.699 0.675
88.781 2 0.535
11.081 554.046 0.554 3 0.596
12.346 617.324 0.617 4 0.604
12.512 625.622 0.626 5 0.572
11.849 592.427 0.592
P3 1 0.468
9.691 484.544 0.485 0.435 0.086 19.643
0.672 64.788
2 0.433 8.965 448.237 0.448
3 0.493 10.210 510.477 0.510
4 0.428 8.861 443.050 0.443
5 0.281 5.811 290.560 0.291
f. Stabilitas Minggu III Suhu 45
