62
Lampiran 5. Ethical clearance penelitian
63
Lampiran 6. Analisis statistik nilai aktivitas serum ALT pada penentuan waktu pencuplikan darah hewan uji
NPar Tests
Descriptive Statistics
N Mean
Std. Deviation Minimum
Maximum ALT
15 1.4053E2
84.31901 51.00
311.00
One-Sample Kolmogorov-Smirnov Test
ALT N
15 Normal Parameters
a
Mean 1.4053E2
Std. Deviation 8.43190E1
Most Extreme Differences Absolute
.204 Positive
.204 Negative
-.157 Kolmogorov-Smirnov Z
.790 Asymp. Sig. 2-tailed
.561 a. Test distribution is Normal.
Oneway
Descriptives
N Mean
Std. Deviation
Std. Error 95 Confidence
Interval for Mean Minimum
Maximum Lower
Bound Upper
Bound jam ke-0
5 73.2000
28.89983 12.92440
37.3161 109.0839
51.00 123.00
jam ke-24 5 2.4640E2
38.02368 17.00471
199.1874 293.6126
219.00 311.00
jam ke-48 5 1.0200E2
32.71085 14.62874
61.3841 142.6159
68.00 139.00
Total 15 1.4053E2
84.31901 21.77107
93.8390 187.2276
51.00 311.00
64
Test of Homogeneity of Variances
ALT Levene Statistic
df1 df2
Sig. .296
2 12
.749
ANOVA ALT
Sum of Squares df
Mean Square F
Sig. Between Groups
86131.733 2
43065.867 38.555
.000 Within Groups
13404.000 12
1117.000 Total
99535.733 14
Post Hoc Tests
Multiple Comparisons
ALT Scheffe
I Waktu_Pen
cuplikan J
Waktu_Pen cuplikan
Mean Difference I-J Std. Error
Sig. 95 Confidence Interval
Lower Bound Upper Bound
jam ke-0 jam ke-24
-173.20000 21.13764
.000 -232.1228
-114.2772 jam ke-48
-28.80000 21.13764
.422 -87.7228
30.1228 jam ke-24 jam ke-0
173.20000 21.13764
.000 114.2772
232.1228 jam ke-48
144.40000 21.13764
.000 85.4772
203.3228 jam ke-48 jam ke-0
28.80000 21.13764
.422 -30.1228
87.7228 jam ke-24
-144.40000 21.13764
.000 -203.3228
-85.4772 . The mean difference is significant at the 0.05 level.
65
Homogeneous Subsets
ALT
Scheffe Waktu_Pencu
plikan N
Subset for alpha = 0.05 1
2 jam ke-0
5 73.2000
jam ke-48 5
102.0000 jam ke-24
5 246.4000
Sig. .422
1.000 Means for groups in homogeneous subsets are displayed.
Graph
66
Lampiran 7. Analisis statistik nilai aktivitas serum AST pada penentuan waktu pencuplikan darah hewan uji
NPar Tests
Descriptive Statistics
N Mean
Std. Deviation Minimum
Maximum AST
15 3.1200E2
211.52575 114.00
669.00
One-Sample Kolmogorov-Smirnov Test
AST N
15 Normal Parameters
a
Mean 3.1200E2
Std. Deviation 2.11526E2
Most Extreme Differences Absolute
.373 Positive
.373 Negative
-.175 Kolmogorov-Smirnov Z
1.446 Asymp. Sig. 2-tailed
.031 a. Test distribution is Normal.
Kruskal-Wallis Test
Ranks
Waktu_Penc uplikan
N Mean Rank
AST jam ke-0
5 3.40
jam ke-24 5
13.00 jam ke-48
5 7.60
Total 15
67
Test Statistics
a,b
AST Chi-Square
11.580 df
2 Asymp. Sig.
.003 a. Kruskal Wallis Test
b. Grouping Variable: Waktu_Pencuplikan
Mann-Whitney Test
Ranks
Waktu_Penc uplikan
N Mean Rank
Sum of Ranks AST
jam ke-0 5
3.00 15.00
jam ke-24 5
8.00 40.00
Total 10
Test Statistics
b
AST Mann-Whitney U
.000 Wilcoxon W
15.000 Z
-2.611 Asymp. Sig. 2-tailed
.009 Exact Sig. [21-tailed Sig.]
.008
a
a. Not corrected for ties. b. Grouping Variable:
Waktu_Pencuplikan
68
Mann-Whitney Test
Ranks
Waktu_Penc uplikan
N Mean Rank
Sum of Ranks AST
jam ke-0 5
3.40 17.00
jam ke-48 5
7.60 38.00
Total 10
Test Statistics
b
AST Mann-Whitney U
2.000 Wilcoxon W
17.000 Z
-2.193 Asymp. Sig. 2-tailed
.028 Exact Sig. [21-tailed Sig.]
.032
a
a. Not corrected for ties. b. Grouping Variable:
Waktu_Pencuplikan
Mann-Whitney Test
Ranks
Waktu_Penc uplikan
N Mean Rank
Sum of Ranks AST
jam ke-24 5
8.00 40.00
jam ke-48 5
3.00 15.00
Total 10
69
Test Statistics
b
AST Mann-Whitney U
.000 Wilcoxon W
15.000 Z
-2.611 Asymp. Sig. 2-tailed
.009 Exact Sig. [21-tailed Sig.]
.008
a
a. Not corrected for ties. b. Grouping Variable:
Waktu_Pencuplikan
Graph
70
Lampiran 8. Analisis statistik nilai
aktivitas ALT serum darah tikus akibat pemberian ekstrak metanol-air daun
M. tanarius dan induksi karbon tetraklorida 2 mlkgBB dengan pengaruh praperlakuan jangka
waktu 30 menit
NPar Tests
One-Sample Kolmogorov-Smirnov Test
ALT N
30 Normal Parameters
a
Mean 1.1543E2
Std. Deviation 6.34718E1
Most Extreme Differences Absolute
.286 Positive
.286 Negative
-.191 Kolmogorov-Smirnov Z
1.566 Asymp. Sig. 2-tailed
.015 a. Test distribution is Normal.
Kruskal-Wallis Test
Ranks
Kelompok_Perlakuan N
Mean Rank ALT
kontrol hepatotoksin 5
28.00 kontrol olive oil
5 10.00
kontrol ekstrak metanol 5
3.00 perlakuan dosis 3840 mgkgBB
5 16.40
perlakuan dosis 1280 mgkgBB 5
12.80 perlakuan dosis 426 mgkgBB
5 22.80
Total 30
71
Test Statistics
a,b
ALT Chi-Square
26.085 df
5 Asymp. Sig.
.000 a. Kruskal Wallis Test
b. Grouping Variable: Kelompok_Perlakuan
Mann-Whitney Test
Ranks
Kelompok_Perlakuan N
Mean Rank Sum of Ranks
ALT kontrol hepatotoksin
5 8.00
40.00 kontrol olive oil
5 3.00
15.00 Total
10
Test Statistics
b
ALT Mann-Whitney U
.000 Wilcoxon W
15.000 Z
-2.611 Asymp. Sig. 2-tailed
.009 Exact Sig. [21-tailed Sig.]
.008
a
a. Not corrected for ties. b. Grouping Variable: Kelompok_Perlakuan
Mann-Whitney Test
Ranks
Kelompok_Perlakuan N
Mean Rank Sum of Ranks
ALT kontrol hepatotoksin
5 8.00
40.00 kontrol ekstrak metanol
5 3.00
15.00 Total
10
72
Test Statistics
b
ALT Mann-Whitney U
.000 Wilcoxon W
15.000 Z
-2.611 Asymp. Sig. 2-tailed
.009 Exact Sig. [21-tailed Sig.]
.008
a
a. Not corrected for ties. b. Grouping Variable: Kelompok_Perlakuan
Mann-Whitney Test
Ranks
Kelompok_Perlakuan N
Mean Rank Sum of Ranks
ALT kontrol hepatotoksin
5 8.00
40.00 perlakuan dosis 3840 mgkgBB
5 3.00
15.00 Total
10
Test Statistics
b
ALT Mann-Whitney U
.000 Wilcoxon W
15.000 Z
-2.611 Asymp. Sig. 2-tailed
.009 Exact Sig. [21-tailed Sig.]
.008
a
a. Not corrected for ties. b. Grouping Variable: Kelompok_Perlakuan
