Introduction 9 Optimization of the Acid Catalyst Concentration for Synthesis of Anti‐Cancer Agent Gamavuton‐0 by Using Mathematical and Statistical Software

3.2. Absolute Measurements Absolute measurements have been conducted every day for one month, during two weeks before and two weeks after the eclipse. The measurements of declinations of each day have been taken around the time of maximum total phase. Especially for the day of eclipse, absolute measurements were taken three times, i.e. with the declinations measurements taken in the beginning phase, during maximum, and at the end of eclipse phase. Results of measurements are depicted in Fig. . a b c d e Figure 7 Blue points are results of weekly absolute measurements during two years time interval 17 September 2014 ‐ 12 October 2016, with red ones are results of daily measurements during one month around the solar eclipse. All component are shown, with a Total, b Horizontal c Vertical and d Declination e Inclination. 3.3. Solar Radiation Measurements Solar Radiations were observed using Phyranometer for one week, i.e. from three days before to three days after the eclipse, with the day of eclipse in the centre of time range. Results of measurements are depicted in Fig. 8, shows that solar radiation was quite low during eclipse time. 448 0 44900 449 0 4 000 4 0 0 4 100 17.09.2014 22.07.201 09.03.201 SE 12.10.201 3713 37140 3714 17.09.2014 22.07.201 09.03.201 SE 12.10.201 ‐2 90 ‐2 70 ‐2 ‐2 30 17.09.2014 22.07.201 09.03.201 SE 12.10.201 1.3 1.4 17.09.2014 22.07.201 09.03.201 SE 12.10.201 ‐34.7 ‐34. ‐34. 17.09.2014 22.07.201 09.03.201 SE 12.10.201 a b Figure 8. Variation recording of Solar Radiatin at LOK, a during 06.03.2016, 00:00 UTC – 12.03.2016, 23:59 UTC. b during 08.03.2016, 21:00 UTC – 09.03.2016, 05:59 UTC. 3.4. Temperature Measurements Temperatures were measured in the Variation Room, as recorded by the data logger MAGDALOG, with z time sampling and averaged in one‐minute. Results of measurements are depicted in Fig. , which shows that the temperature were mainly stable during the observation days – °C . owever, the temperature were slightly lower on the eclipse time. a b Figure 9. Variation recording of Temperature measured in the Variation Room of LOK, a during 02.03.2016‐ 16.03.2016, and b during 08.03.2016, 21:00 UTC – 09.03.2016, 05:59 UTC.

4. Spectrum of Variation Recording

The variation recordings of total fields F are analyzed to get the spectrum for frequency range , z. The normalized values of power spectral densities are reaching the maximum point of , on th March at f= z, while on other days are , on nd March at f= z, , on th March at f= z, , on th at f= z, , on th at f= z, and , 8 on th at f= , z. Results of spectrum analysis are depicted in Fig. . t can be concluded that the low frequencies are higher on the days before and after the eclipse. t means that the low frequency and contributions of internal sources to the total fields are reaching the minimum value on the solar eclipse day. ‐400 ‐200 200 400 00 800 1000 00 .0 12 .0 00 .0 12 .0 00 .0 12 .0 00 .0 12 .0 00 .0 12 .0 00 .0 12 .0 00 .0 12 .0 So la r Ra di at io n W m Time UTC ‐300.00 ‐200.00 ‐100.00 0.00 100.00 200.00 300.00 400.00 00.00 00.00 700.00 800.00 21 .0 22 .0 23 .0 00 .0 01 .0 02 .0 03 .0 04 .0 .0 So la r Ra di at io n W m Time UTC 1 21 41 61 81 101 121 141 161 181 200 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 20 22 24 26 28 30 32 Minute March 2016 Tem pera ture oC 27.2 27.4 27.6 27.8 28 28.2 28.4 28.6 28.8 29 ‐0.80 ‐0.70 ‐0. 0 ‐0. 0 ‐0.40 ‐0.30 ‐0.20 ‐0.10 0.00 21 .0 22 .0 23 .0 00 .0 01 .0 02 .0 03 .0 04 .0 .0 Variat io n of T °C Time UTC